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Gene: Adgrf1 MGI:1924846

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Registered for phenotyping at IMPC

Phenotyping is planned for a knockout strain of this gene but data is not currently available.

Gene Summary

Name:
adhesion G protein-coupled receptor F1
Synonyms:
Gpr110,  5031409J19Rik

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Adgrf1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.
No human diseases associated to this gene by phenotypic similarity.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Adgrf1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Adgrf1.

There are 5 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation. Journal of neuroinflammation (August 2023) Adgrf1tm1a(KOMP)Wtsi PMC10426059
GPR110 ligands reduce chronic optic tract gliosis and visual deficit following repetitive mild traumatic brain injury in mice. Journal of neuroinflammation (July 2021) Adgrf1tm1a(KOMP)Wtsi PMC8286622
Ligand-Induced GPR110 Activation Facilitates Axon Growth after Injury. International journal of molecular sciences (March 2021) Adgrf1tm1a(KOMP)Wtsi PMC8037074
GPR110 (ADGRF1) mediates anti-inflammatory effects of N-docosahexaenoylethanolamine. Journal of neuroinflammation (November 2019) Adgrf1tm1a(KOMP)Wtsi PMC6858791
Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function. Nature communications (October 2016) Adgrf1tm1a(KOMP)Wtsi PMC5075789

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All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Adgrf1em1(IMPC)Ccpcz Exon Deletion Mice
Adgrf1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Adgrf1tm43780(L1L2_gt0) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Adgrf1tm43780(L1L2_st1) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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