Gene: Coq6

Order

Name coenzyme Q6 monooxygenase

Synonyms 5930427M12Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1924408    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Coq6

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Coq6 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Coq6tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 9.5 0.0
abnormal embryo size Coq6tm1b(EUCOMM)Hmgu HET Female Male embryonic day 9.5 0.0
abnormal embryo turning Coq6tm1b(EUCOMM)Hmgu HET Male embryonic day 9.5 0.0
abnormal embryo turning Coq6tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 9.5 0.0
abnormal neural tube closure Coq6tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 9.5 0.0
abnormal tail bud morphology Coq6tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 9.5 0.0
embryonic growth retardation Coq6tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 9.5 0.0
embryonic growth retardation Coq6tm1b(EUCOMM)Hmgu HET Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Coq6tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Coq6tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
increased circulating sodium level Coq6tm1b(EUCOMM)Hmgu HET Female Male postnatal 4.55E-7
persistence of hyaloid vascular system Coq6tm1b(EUCOMM)Hmgu HET Male postnatal 1.98E-6
abnormal vitreous body morphology Coq6tm1b(EUCOMM)Hmgu HET Female postnatal 1.04E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No (4/393)
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Submandibular gland 2 No (1/104)
Testis 2 No (4/562) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Urinary bladder 2 No
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    reproductive system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/482)
Dorsal root ganglion 1 (1/45)
Ear 1 (1/482)
Embryo 1 (1/482)
Eye 1 (1/482)
Foot 1 (1/482)
Forebrain 1 (1/482)
Forelimb 1 (1/482)
Fronto-nasal process 1 (1/46)
Hand 1 (1/482)
Head 1 (5/482)
Heart 1 (1/482)
Hindbrain 1 (6/482)
Hindlimb 1 (1/482)
Liver 1 (1/482)
Lung 1 (1/482)
Mandibular process 1 (1/482)
Maxillary process 1 (1/482)
Midbrain 1 (1/482)
Nose 1 (1/47)
Oral cavity 1 (1/482)
Skin 1 (1/482)
Spinal cord 1 (1/46)
Tail 1 (1/482)
Tail somite 1 (1/482)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    21 Images
  • X-ray: XRay Images Forepaw
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    11 Images
  • Sleep Wake: Wake state (bmp file)
    2 Images
  • X-ray: XRay Images Dorso Ventral
    21 Images
  • Eye Morphology: Images Slit Lamp
    1 Images
  • Gross Morphology Embryo E9.5
    4 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Coq6tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Coq6tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene