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Gene: Idnk MGI:1922981

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
idnK gluconokinase homolog (E. coli)
Synonyms:
5133401N09Rik

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Idnk mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Idnk by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Contractures-Ectodermal Dysplasia-Cleft Lip/Palate Syndrome
Lacrimation abnormality, Cognitive impairment ORPHA:1484
Hyperuricemia, Infantile, With Abnormal Behavior And Normal Hypoxanthine Guanine Phosphoribosyltransferase
Alacrima OMIM:240000
Corneal Dystrophy, Meesmann, 2
Epiphora OMIM:618767
Alacrima, Congenital, Autosomal Recessive
Alacrima OMIM:601549
Epithelial Recurrent Erosion Dystrophy
Epiphora OMIM:122400
Dacryocystitis-Osteopoikilosis Syndrome
Lacrimation abnormality ORPHA:1562
Alacrima, Congenital, Autosomal Dominant
Alacrima, Decreased lacrimation OMIM:103420
Corneal Dystrophy, Meesmann, 1
Epiphora OMIM:122100
Paroxysmal Extreme Pain Disorder
Lacrimation abnormality OMIM:167400
Keratosis Pilaris Atrophicans
Epiphora OMIM:604093
Neuropathy, Hereditary Sensory And Autonomic, Type I, With Cough And Gastroesophageal Reflux
Alacrima OMIM:608088
Keratoendotheliitis Fugax Hereditaria
Epiphora OMIM:148200
Intellectual Developmental Disorder, X-Linked, Syndromic 17
Alacrima OMIM:300858
Classic Progressive Supranuclear Palsy Syndrome
Mental deterioration, Decreased lacrimation, Social and occupational deterioration ORPHA:240071
Neuropathy, Hereditary Sensory And Autonomic, Type Viii
Decreased lacrimation OMIM:616488
Keratitis-Ichthyosis-Deafness Syndrome, Autosomal Recessive
Decreased lacrimation OMIM:242150
Arrhinia-Choanal Atresia-Microphthalmia Syndrome
Lacrimation abnormality ORPHA:1135
Marsili Syndrome
Lacrimation abnormality OMIM:147430
Hypohidrotic Ectodermal Dysplasia-Hypothyroidism-Ciliary Dyskinesia Syndrome
Lacrimation abnormality ORPHA:1882
Hydroa Vacciniforme
Epiphora ORPHA:330058
Intellectual Disability-Alacrima-Achalasia Syndrome
Alacrima ORPHA:289483
Lacrimoauriculodentodigital Syndrome 2
Alacrima OMIM:620192
Frontonasal Dysplasia 2
Decreased lacrimation OMIM:613451
Graft Versus Host Disease
Decreased lacrimation ORPHA:39812
Limbal Stem Cell Deficiency
Lacrimation abnormality, Epiphora ORPHA:171673
Cockayne Syndrome Type 1
Decreased lacrimation ORPHA:90321
Lacrimal Duct Defect
Epiphora OMIM:149700
Focal Facial Dermal Dysplasia Type Iii
Lacrimation abnormality ORPHA:1807
Glucocorticoid Deficiency 2
Alacrima OMIM:607398
Lacrimoauriculodentodigital Syndrome 3
Alacrima OMIM:620193
Blepharonasofacial Malformation Syndrome
Lacrimation abnormality ORPHA:1252
Peripheral Demyelinating Neuropathy, Central Dysmyelination, Waardenburg Syndrome, And Hirschsprung Disease
Alacrima, Decreased lacrimation OMIM:609136
Stuve-Wiedemann Syndrome 1
Decreased lacrimation OMIM:601559
Otofaciocervical Syndrome 2, With T-Cell Deficiency
Alacrima OMIM:615560
Kilquist Syndrome
Alacrima OMIM:619080
Chondroectodermal Dysplasia With Night Blindness
Epiphora ORPHA:319195
Isolated Congenital Alacrima
Alacrima ORPHA:91416
Cockayne Syndrome
Cognitive impairment, Alacrima, Decreased lacrimation, Mental deterioration ORPHA:191
Achalasia-Addisonianism-Alacrima Syndrome
Alacrima OMIM:231550
Cockayne Syndrome A
Decreased lacrimation, Dementia OMIM:216400
Alacrimia-Choreoathetosis-Liver Dysfunction Syndrome
Decreased lacrimation ORPHA:404454
Sunct Syndrome
Increased tear production, Epiphora ORPHA:57145
Helix Syndrome
Alacrima OMIM:617671
Neurodevelopmental Disorder With Dysmorphic Facies, Impaired Speech, And Hypotonia
Attention deficit hyperactivity disorder, Alacrima OMIM:619005
Gelatinous Drop-Like Corneal Dystrophy
Epiphora ORPHA:98957
Cone-Rod Dystrophy 10
Epiphora OMIM:610283
Neuropathy, Hereditary Sensory And Autonomic, Type Iii
Alacrima OMIM:223900
Trisomy 8P
Decreased lacrimation ORPHA:264450
Cockayne Syndrome B
Decreased lacrimation OMIM:133540
Paroxysmal Hemicrania
Epiphora ORPHA:157835
Peripheral Demyelinating Neuropathy-Central Dysmyelinating Leukodystrophy-Waardenburg Syndrome-Hirschsprung Disease
Decreased lacrimation ORPHA:163746
Familial Dysautonomia
Alacrima ORPHA:1764
Alacrima, Achalasia, And Impaired Intellectual Development Syndrome
Alacrima OMIM:615510
Neuropathy, Hereditary Sensory And Autonomic, Type Vi
Alacrima OMIM:614653
Hyperostosis Cranialis Interna
Epiphora OMIM:144755
Multiple Congenital Anomalies-Hypotonia-Seizures Syndrome 4
Alacrima OMIM:618548
Waardenburg Syndrome Type 1
Lacrimation abnormality ORPHA:894
Epithelial Recurrent Erosion Dystrophy
Epiphora ORPHA:293381
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 18
Alacrima OMIM:615356
Nasopalpebral Lipoma-Coloboma Syndrome
Epiphora OMIM:167730
Ankyloblepharon-Ectodermal Defects-Cleft Lip/Palate
Alacrima OMIM:106260
Cone-Rod Dystrophy 8
Epiphora OMIM:605549
Acrocraniofacial Dysostosis
Lacrimation abnormality ORPHA:949
Neurotrophic Keratopathy
Lacrimation abnormality ORPHA:137596
Branchiootorenal Syndrome 1
Lacrimation abnormality, Gustatory lacrimation OMIM:113650
Deeah Syndrome
Alacrima OMIM:619004
Postaxial Polydactyly-Dental And Vertebral Anomalies Syndrome
Lacrimation abnormality ORPHA:2916
Congenital Disorder Of Deglycosylation 1
Alacrima OMIM:615273
Carcinoid Syndrome
Epiphora ORPHA:100093
Herpes Simplex Virus Stromal Keratitis
Epiphora ORPHA:137599
Dyskeratosis Congenita, Autosomal Recessive 6
Epiphora OMIM:616353
Johanson-Blizzard Syndrome
Lacrimation abnormality ORPHA:2315
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome
Decreased lacrimation ORPHA:293987
Posterior Polymorphous Corneal Dystrophy
Lacrimation abnormality ORPHA:98973
Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome Plus
Decreased lacrimation ORPHA:572333
Waardenburg Syndrome
Lacrimation abnormality ORPHA:3440
Nasolacrimal Duct Cyst
Epiphora ORPHA:141083
Schinzel-Giedion Syndrome
Alacrima ORPHA:798
Vernal Keratoconjunctivitis
Epiphora ORPHA:70476
Nasopalpebral Lipoma-Coloboma Syndrome
Epiphora ORPHA:2399
Dyskeratosis Congenita, Autosomal Recessive 1
Epiphora OMIM:224230
Corneal Dystrophy, Posterior Polymorphous, 1
Epiphora OMIM:122000
Mucoepithelial Dysplasia, Hereditary
Epiphora OMIM:158310
Dyskeratosis Congenita, Digenic
Epiphora OMIM:620040
Oculocerebrorenal Syndrome Of Lowe
Attention deficit hyperactivity disorder, Lacrimation abnormality ORPHA:534
Eec Syndrome
Lacrimation abnormality ORPHA:1896
Dyskeratosis Congenita, Autosomal Dominant 3
Epiphora OMIM:613990
Charge Syndrome
Attention deficit hyperactivity disorder, Lacrimation abnormality ORPHA:138
Persistent Hyperplastic Primary Vitreous
Epiphora ORPHA:91495
Williams Syndrome
Attention deficit hyperactivity disorder, Lacrimation abnormality ORPHA:904
Stüve-Wiedemann Syndrome
Lacrimation abnormality ORPHA:3206
Lacrimoauriculodentodigital Syndrome 1
Alacrima OMIM:149730
Amoebiasis Due To Free-Living Amoebae
Confusion, Increased tear production ORPHA:68
Dyskeratosis Congenita, X-Linked
Epiphora OMIM:305000
Sarcoidosis, Susceptibility To, 1
Epiphora OMIM:181000
Lacrimoauriculodentodigital Syndrome
Epiphora ORPHA:2363
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Spectrum
Increased tear production ORPHA:95455

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Idnk

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Idnk.

No publications found that use IMPC mice or data for Idnk.

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MGI Allele Allele Type Produced
Idnktm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Idnktm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells

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