Gene: Med25


Name mediator complex subunit 25

  • ESTM2
  • 2610034E13Rik
  • 2610529E18Rik

Status ES CellsMice
phenotype data available

Links MGI:1922863    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Med25

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Med25 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Med25tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
decreased total retina thickness Med25tm1b(KOMP)Wtsi HET Female Male postnatal 2.05E-11
short tibia Med25tm1b(KOMP)Wtsi HET Female postnatal 7.21E-7
abnormal motor capabilities/coordination/movement Med25tm1b(KOMP)Wtsi HET Female Male postnatal 2.97E-6
abnormal behavior Med25tm1b(KOMP)Wtsi HET Female Male postnatal 4.37E-6
increased or absent threshold for auditory brainstem response Med25tm1b(KOMP)Wtsi HET Female Male postnatal 5.7E-6

Download data as: TSV XLS


Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    13 Images
  • X-ray: XRay Images Dorso Ventral
    13 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Med25tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Med25tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)