Gene: Mindy1

Order

Name MINDY lysine 48 deubiquitinase 1

Synonyms
  • cI-40
  • Fam63a
  • 1810005H09Rik
  • 4930504E06Rik
  • NF-E2 inducible protein

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1922257    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Mindy1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Mindy1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal locomotor activation Mindy1tm1a(EUCOMM)Wtsi HOM Female Male postnatal 8.25E-10
abnormal spine curvature Mindy1tm1b(EUCOMM)Wtsi HOM Male postnatal 6.14E-9
hyperactivity Mindy1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.25E-7
decreased total body fat amount Mindy1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.72E-6
corneal opacity Mindy1tm1b(EUCOMM)Wtsi HOM Female postnatal 3.85E-6
increased hemoglobin content Mindy1tm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.27E-5
increased bone mineral content Mindy1tm1b(EUCOMM)Wtsi HOM Female Male postnatal 8.09E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/2)
Adrenal gland 2 No (5/393) (2/2)
Aorta 4 No (1/562) (2/4)
Blood vessel 2 No (2/2)
Bone 4 No (1/539) (4/4)
Brain 4 No (6/562) (4/4)
Brainstem 4 No (4/562) (2/4)
Brown adipose tissue 2 No
Brown adipose tissue 2 No
Cartilage tissue 4 No (1/562) (4/4)
Cerebellum 4 No (4/562) (2/4)
Cerebral cortex 4 No (5/562) (2/4)
Esophagus 2 No (2/393) (2/2)
Eye 4 No (1/562) (4/4)
Gall bladder 4 No (4/4)
Heart 4 No (3/562) (4/4)
Hippocampus 4 No (5/562) (2/4)
Hypothalamus 4 No (4/562) (2/4)
Kidney 4 No (20/562) (4/4)
Large intestine 4 No (12/562) (2/4)
Liver 4 No (4/4)
Lower urinary tract 4 No (3/562) (2/4)
Lung 4 No (3/562) (4/4)
Lymph node 4 No (1/562) (4/4)
Mammary gland 4 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Olfactory lobe 2 No
Oral epithelium 2 No
Ovary 4 No (1/562) (2/4)
Oviduct 4 No (2/562) (2/4)
Pancreas 4 No (6/562) (4/4)
Parathyroid gland 4 No (2/540) (4/4)
Peripheral nervous system 4 No (3/562) (4/4)
Peyer's patch 2 No
Peyer's patch 2 No (1/393) (1/2)
Pituitary gland 4 No (1/562) (4/4)
Prostate gland 4 No (5/562) (1/4)
Skeletal muscle 2 No (2/2)
Skeletal muscle tissue 2 No (2/2)
Skin 4 No (1/562) (4/4)
Small intestine 4 No (11/562) (2/4)
Spinal cord 4 No (3/562) (4/4)
Spleen 4 No (4/562) (1/4)
Stomach 4 No (9/562) (4/4)
Striatum 4 No (4/562) (2/4)
Testis 4 No (4/562) (2/4)
Thymus 4 No (2/4)
Thyroid gland 4 No (16/562) (3/4)
Trachea 4 No (3/562) (4/4)
Uterus 4 No (2/562) (2/4)
Vascular system 2 No (1/393)
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/440) (3/4)
Ear 2 (1/440) (1/4)
Embryo 2 (1/440) (4/4)
Eye 2 (1/440) (3/4)
Foot 2 (1/4)
Forebrain 2 (1/440) (3/4)
Forelimb 2 (1/440) (3/4)
Hand 2 (1/4)
Head 2 (5/440) (3/4)
Heart 2 (1/440) (2/4)
Hindbrain 2 (5/440) (3/4)
Hindlimb 2 (1/440) (3/4)
Liver 2 (1/440) (1/4)
Lung 2 (1/440) (1/4)
Mandibular process 2 (1/440) (1/4)
Maxillary process 2 (1/440) (1/4)
Midbrain 2 (1/440) (3/4)
Oral cavity 2 (1/440) (2/4)
Skin 2 (1/440) (1/4)
Tail 2 (1/440) (3/4)
Tail somite 2 (1/440) (2/4)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    12 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    12 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Adult LacZ: LacZ Images Wholemount
    24 Images
  • Echo: M-Mode Images
    32 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Mindy1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Mindy1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Mindy1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene