Gene: Lonrf3

Order

Name LON peptidase N-terminal domain and ring finger 3

Synonyms
  • Rnf127
  • A830039N02Rik
  • 5730439E01Rik
  • 4932412G04Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1921615    Ensembl Gene    Ensembl Orthologs    My Genes   

Phenotype associations for Lonrf3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Lonrf3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased circulating free fatty acid level Lonrf3tm1a(KOMP)Wtsi HEM Male postnatal 4.14E-6
increased circulating magnesium level Lonrf3tm1a(KOMP)Wtsi HEM Male postnatal 2.45E-5
increased circulating calcium level Lonrf3tm1a(KOMP)Wtsi HOM Female postnatal 4.68E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No (3/6)
Aorta 3 No (1/562) (1/6)
Blood vessel 3 No
Bone 3 No (1/539)
Brain 3 No (6/562) (6/6)
Brainstem 3 No (4/562) (5/6)
Brown adipose tissue 3 No
Cartilage tissue 3 No (1/562)
Cerebellum 3 No (4/562) (5/6)
Cerebral cortex 3 No (5/562) (6/6)
Eye 3 No (1/562) (3/6)
Gall bladder 3 No
Heart 3 No (3/562)
Hippocampus 3 No (5/562) (6/6)
Hypothalamus 3 No (4/562) (5/6)
Kidney 3 No (20/562) (6/6)
Large intestine 3 No (12/562) (2/6)
Liver 3 No (3/6)
Lower urinary tract 3 No (3/562) (4/6)
Lung 3 No (3/562) (6/6)
Lymph node 3 No (1/562)
Mammary gland 3 No
Esophagus 3 No
Olfactory lobe 3 No (6/6)
Ovary 3 No (1/562)
Oviduct 3 No (2/562) (3/6)
Pancreas 3 No (6/562) (1/6)
Parathyroid gland 3 No (2/540)
Peripheral nervous system 3 No (3/562) (5/6)
Peyer's patch 3 No
Pituitary gland 3 No (1/562) (1/6)
Prostate gland 3 No (5/562)
Skeletal muscle tissue 3 No
Skin 3 No (1/562) (2/6)
Small intestine 3 No (11/562)
Spinal cord 3 No (3/562) (4/6)
Spleen 3 No (4/562)
Stomach 3 No (9/562)
Striatum 3 No (4/562) (5/6)
Testis 3 No (4/562) (3/6)
Thymus 3 No
Thyroid gland 3 No (16/562) (4/6)
Trachea 3 No (3/562)
Uterus 3 No (2/562)
White adipose tissue 3 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse respiratory system endocrine system digestive system cardiovascular system nervous system sensory organ reproductive system integumental system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (19)
  • Lonrf3tm1a(KOMP)Wtsi
    URINARY BLADDER, LOWER URINARY TRACT, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    PANCREAS, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    SPINAL CORD, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    KIDNEY, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    TESTIS, HEMI, Male, WTSI

show all 19 images

nervous system (6)
  • Lonrf3tm1a(KOMP)Wtsi
    SPINAL CORD, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    PERIPHERAL NERVOUS SYSTEM, TRIGEMINAL V NERVE, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    STRIATUM, HEMI, Male, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    BRAINSTEM, HEMI, Male, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    SPINAL CORD, HET, Female, WTSI

show all 6 images

endocrine system (4)
  • Lonrf3tm1a(KOMP)Wtsi
    THYROID GLAND, HET, Female, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    THYROID GLAND, HEMI, Male, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    ADRENAL GLAND, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    ADRENAL GLAND, HET, Female, WTSI
reproductive system (4)
  • Lonrf3tm1a(KOMP)Wtsi
    TESTIS, HEMI, Male, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    OVIDUCT, HET, Female, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    OVARY, HET, Female, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    TESTIS, HEMI, Male, WTSI
urinary system (4)
  • Lonrf3tm1a(KOMP)Wtsi
    URINARY BLADDER, LOWER URINARY TRACT, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    KIDNEY, HEMI, Male, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    KIDNEY, HET, Female, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    URINARY BLADDER, LOWER URINARY TRACT, HEMI, Male, WTSI
digestive system (3)
  • Lonrf3tm1b(KOMP)Wtsi
    LARGE INTESTINE, HET, Female, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    LIVER, HEMI, Male, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    LIVER, HET, Female, WTSI
respiratory system (2)
  • Lonrf3tm1b(KOMP)Wtsi
    LUNG, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    LUNG, HEMI, Male, WTSI
sensory organ (2)
  • Lonrf3tm1a(KOMP)Wtsi
    EYE, HEMI, Male, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    EYE, HEMI, Male, WTSI
cardiovascular system (1)
  • Lonrf3tm1a(KOMP)Wtsi
    AORTA, HEMI, Male, WTSI
integumental system (1)
  • Lonrf3tm1b(KOMP)Wtsi
    SKIN, HET, Female, WTSI

Associated Images

Associated Images
  • DSS Histology
    8 Images
  • Eye Morphology: Images Ophthalmoscopy
    3 Images
  • X-ray: XRay Images Dorso Ventral
    83 Images
  • X-ray: XRay Images Lateral Orientation
    55 Images
  • X-ray: XRay Images Forepaw
    28 Images
  • X-ray: XRay Images Skull Lateral Orientation
    27 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    27 Images
  • Anti-nuclear antibody assay
    6 Images
  • Eye Morphology: Images Slit Lamp
    1 Images
Legacy Phenotype Associated Images
Xray (168)
  • Lonrf3tm1a(KOMP)Wtsi
    WT, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    WT, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    WT, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    WT, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    WT, Male, WTSI

show all 168 images

Brain Histopathology (12)
  • Lonrf3tm1a(KOMP)Wtsi
    HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    LATERAL VENTRICLE, enlarged lateral ventricles, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    LATERAL VENTRICLE, enlarged lateral ventricles, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    HEMI, Male, WTSI

show all 12 images

Eye Morphology (4)
  • Lonrf3tm1a(KOMP)Wtsi
    abnormal retinal pigmentation, HOM, Female, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    abnormal retinal pigmentation, HEMI, Male, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    LEFT EYE, HOM, Female, WTSI
  • Lonrf3tm1a(KOMP)Wtsi
    abnormal retinal pigmentation, HEMI, Male, WTSI
Histology Slide (3)
  • Lonrf3tm1a(KOMP)Wtsi
    HEMI, Male, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    HET, Female, WTSI
  • Lonrf3tm1b(KOMP)Wtsi
    HET, Female, WTSI
Anti-nuclear Antibody Assay (1)
  • Lonrf3tm1b(KOMP)Wtsi
    WT, Male, WTSI
Skin Histopathology (1)
  • Lonrf3tm1a(KOMP)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Lonrf3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Lonrf3tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Lonrf3tm41056(L1L2_gt0)
Vector
Gene