Gene: Rhobtb3

Order

Name Rho-related BTB domain containing 3

Synonyms
  • 2610033K01Rik
  • 1700040C17Rik
  • 4930503C18Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1920546    Ensembl Gene    Ensembl Orthologs    My Genes   

Phenotype associations for Rhobtb3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rhobtb3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased body length Rhobtb3tm1a(KOMP)Wtsi HOM Female Male postnatal 1.91E-22
decreased body weight Rhobtb3tm1a(KOMP)Wtsi HOM Female Male postnatal 1.09E-12
decreased lean body mass Rhobtb3tm1a(KOMP)Wtsi HOM Female Male postnatal 7.95E-8
abnormal tooth morphology Rhobtb3tm1a(KOMP)Wtsi HOM Male postnatal 3.19E-7
decreased bone mineral content Rhobtb3tm1a(KOMP)Wtsi HOM Female Male postnatal 7.28E-7
abnormal cranium morphology Rhobtb3tm1a(KOMP)Wtsi HOM Male postnatal 8.53E-6
abnormal joint morphology Rhobtb3tm1a(KOMP)Wtsi HOM Male postnatal 1.36E-5
decreased total body fat amount Rhobtb3tm1a(KOMP)Wtsi HOM Female Male postnatal 1.98E-5
abnormal snout morphology Rhobtb3tm1a(KOMP)Wtsi HOM Male postnatal 2.25E-5
increased mean corpuscular volume Rhobtb3tm1a(KOMP)Wtsi HOM Female Male postnatal 5.42E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No (2/2)
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No (1/2)
Heart 2 No (2/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No (1/2)
Lower urinary tract 2 No (2/2)
Lung 2 No
Lymph node 2 No (2/2)
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No (2/2)
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system endocrine system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system trunk postnatal mouse nervous system immune system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (20)
  • Rhobtb3tm1a(KOMP)Wtsi
    peripheral nervous system, pituitary gland, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    bone, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    heart, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    spleen, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    oesophagus, HET, Female, WTSI

show all 20 images

trunk (10)
  • Rhobtb3tm1a(KOMP)Wtsi
    heart, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    spleen, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    oesophagus, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI

show all 10 images

nervous system (4)
  • Rhobtb3tm1a(KOMP)Wtsi
    peripheral nervous system, pituitary gland, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    brain, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    brain, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    spinal cord, HET, Female, WTSI
digestive system (3)
  • Rhobtb3tm1a(KOMP)Wtsi
    oesophagus, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    large intestine, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    small intestine, HET, Female, WTSI
immune system (2)
  • Rhobtb3tm1a(KOMP)Wtsi
    spleen, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    lymph node, HET, Female, WTSI
musculoskeletal system (2)
  • Rhobtb3tm1a(KOMP)Wtsi
    bone, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    skeletal muscle tissue, HET, Female, WTSI
reproductive system (2)
  • Rhobtb3tm1a(KOMP)Wtsi
    testis, HET, Male, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    ovary, HET, Female, WTSI
urinary system (2)
  • Rhobtb3tm1a(KOMP)Wtsi
    kidney, HET, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
adipose tissue (1)
  • Rhobtb3tm1a(KOMP)Wtsi
    inguinal fat pad, HET, Female, WTSI
cardiovascular system (1)
  • Rhobtb3tm1a(KOMP)Wtsi
    heart, HET, Female, WTSI
endocrine system (1)
  • Rhobtb3tm1a(KOMP)Wtsi
    parathyroid gland, HET, Female, WTSI
integumental system (1)
  • Rhobtb3tm1a(KOMP)Wtsi
    skin, HET, Female, WTSI
set of connective tissues (1)
  • Rhobtb3tm1a(KOMP)Wtsi
    inguinal fat pad, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (186)
  • Rhobtb3tm1a(KOMP)Wtsi
    body, WT, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    head, WT, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    head, WT, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    forearm, WT, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    head, WT, Female, WTSI

show all 186 images

Skin Histopathology (9)
  • Rhobtb3tm1a(KOMP)Wtsi
    back skin, WT, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    back skin, WT, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    back skin, WT, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    back skin, HOM, Female, WTSI

show all 9 images

Eye Morphology (3)
  • Rhobtb3tm1a(KOMP)Wtsi
    left eye, WT, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    right eye, WT, Female, WTSI
  • Rhobtb3tm1a(KOMP)Wtsi
    left eye, WT, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rhobtb3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene