Gene: Gpr22

Order

Name G protein-coupled receptor 22

Synonyms 2900068K05Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1920260    Ensembl Gene    Ensembl Orthologs    My Genes    IDG   

Viability Homozygous - Viable

Phenotype associations for Gpr22

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Gpr22 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased lean body mass Gpr22tm1b(KOMP)Wtsi HOM Male postnatal 9.94E-9
decreased total body fat amount Gpr22tm1b(KOMP)Wtsi HOM Male postnatal 1.06E-8
hyperactivity Gpr22tm1b(KOMP)Wtsi HOM Female Male postnatal 3.5E-8
increased circulating creatinine level Gpr22tm1b(KOMP)Wtsi HOM Female Male postnatal 1.22E-5
abnormal gait Gpr22tm1b(KOMP)Wtsi HOM Male postnatal 6.21E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No
Gall bladder 2 No
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Oral epithelium 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    digestive system
    cardiovascular system
    nervous system
    reproductive system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3 (6/485) (5/5)
Ear 3 (1/485)
Embryo 3 (1/485) (5/5)
Eye 3 (1/485)
Foot 3 (1/485)
Forebrain 3 (1/485) (2/5)
Forelimb 3 (1/485) (2/5)
Hand 3 (1/485)
Head 3 (5/485) (5/5)
Heart 3 (1/485) (4/5)
Hindbrain 3 (6/485) (5/5)
Hindlimb 3 (1/485) (2/5)
Liver 3 (1/485)
Lung 3 (1/485)
Mandibular process 3 (1/485)
Maxillary process 3 (1/485)
Midbrain 3 (1/485) (1/5)
Oral cavity 3 (1/485)
Skin 3 (1/485)
Tail 3 (1/485)
Tail somite 3 (1/485)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Echo: M-Mode Images
    31 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • X-ray: XRay Images Dorso Ventral
    12 Images
  • Adult LacZ: LacZ Images Wholemount
    11 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    12 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Gpr22tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Gpr22tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene