Gene: Ush1c

Name USH1 protein network component harmonin

Synonyms
  • harmonin
  • Usher syndrome 1C
  • 2010016F01Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1919338   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Ush1c

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ush1c data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
impaired righting response Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 1.81E-21
stereotypic behavior Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 2.05E-21
absent pinna reflex Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 8.16E-20
trunk curl Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 2.67E-18
decreased grip strength Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 3.46E-15
improved glucose tolerance Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 2.56E-13
increased lean body mass Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 1.1E-10
decreased total body fat amount Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 1.72E-10
increased bone mineral content Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 1.96E-10
increased circulating chloride level Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 5.06E-9
decreased circulating insulin level Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 1.68E-8
increased or absent threshold for auditory brainstem response Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 1.0E-7
decreased circulating glucose level Ush1ctm1a(KOMP)Wtsi HOM Male postnatal 3.83E-6
decreased circulating amylase level Ush1ctm1a(KOMP)Wtsi HOM Male postnatal 1.02E-5
decreased circulating triglyceride level Ush1ctm1a(KOMP)Wtsi HOM Male postnatal 1.03E-5
decreased circulating potassium level Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 2.58E-5
increased circulating sodium level Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 5.87E-5
limb grasping Ush1ctm1a(KOMP)Wtsi HOM Female Male postnatal 7.69E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Lateral Orientation
    27 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Skull Lateral Orientation
    13 Images
Legacy Phenotype Associated Images
Xray (85)
  • Ush1ctm1a(KOMP)Wtsi
    HEAD, HOM, Male, WTSI
  • Ush1ctm1a(KOMP)Wtsi
    HEAD, HOM, Male, WTSI
  • Ush1ctm1a(KOMP)Wtsi
    FORELIMB, HOM, Male, WTSI
  • Ush1ctm1a(KOMP)Wtsi
    TRUNK, HOM, Female, WTSI
  • Ush1ctm1a(KOMP)Wtsi
    TRUNK, HOM, Female, WTSI

show all 85 images

Tail Epidermis Wholemount (4)
  • Ush1ctm1a(KOMP)Wtsi
    abnormal hair follicle morphology, HET, Female, WTSI
  • Ush1ctm1a(KOMP)Wtsi
    abnormal hair follicle morphology, HET, Female, WTSI
  • Ush1ctm1a(KOMP)Wtsi
    abnormal hair follicle morphology, HET, Female, WTSI
  • Ush1ctm1a(KOMP)Wtsi
    abnormal hair follicle morphology, HET, Female, WTSI
Skin Histopathology (2)
  • Ush1ctm1a(KOMP)Wtsi
    HOM, Female, WTSI
  • Ush1ctm1a(KOMP)Wtsi
    HET, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Ush1ctm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene