Gene: Ptges2

Order

Name prostaglandin E synthase 2

Synonyms
  • GBF-1
  • GBF1
  • 0610038H10Rik

Status ES CellsMice
tm1a
phenotype data available

Links MGI:1917592    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Ptges2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ptges2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased mean corpuscular hemoglobin Ptges2tm1a(EUCOMM)Wtsi HOM Female Male postnatal 5.19E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No (2/2)
Bone 2 No (1/539) (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562) (2/2)
Gall bladder 2 No (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (1/2)
Liver 2 No
Lower urinary tract 2 No (3/562) (2/2)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (1/2)
Mammary gland 2 No
Esophagus 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Parathyroid gland 2 No (2/540) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (1/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Uterus 2 No (2/562) (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system endocrine system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system sensory organ immune system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (14)
  • Ptges2tm1a(EUCOMM)Wtsi
    ADRENAL GLAND, HET, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    TRACHEA, PARATHYROID GLAND, THYROID GLAND, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    OVIDUCT, OVARY, UTERUS, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    HEART, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    ESOPHAGUS, HET, Male, WTSI

show all 14 images

digestive system (4)
  • Ptges2tm1a(EUCOMM)Wtsi
    ESOPHAGUS, HET, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    PEYER'S PATCH, SMALL INTESTINE, HET, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    LARGE INTESTINE, HET, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    GALL BLADDER, HET, Female, WTSI
cardiovascular system (3)
  • Ptges2tm1a(EUCOMM)Wtsi
    HEART, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    SPLEEN, BLOOD VESSEL, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    BLOOD VESSEL, HET, Female, WTSI
immune system (3)
  • Ptges2tm1a(EUCOMM)Wtsi
    MESENTERIC LYMPH NODE, LYMPH NODE, HET, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    PEYER'S PATCH, SMALL INTESTINE, HET, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    SPLEEN, BLOOD VESSEL, HET, Female, WTSI
integumental system (3)
  • Ptges2tm1a(EUCOMM)Wtsi
    SKIN, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    INGUINAL FAT PAD, MAMMARY GLAND, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    SKIN, HET, Female, WTSI
nervous system (3)
  • Ptges2tm1a(EUCOMM)Wtsi
    PERIPHERAL NERVOUS SYSTEM, PITUITARY GLAND, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    BRAIN, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    SPINAL CORD, HET, Female, WTSI
adipose tissue (2)
  • Ptges2tm1a(EUCOMM)Wtsi
    INGUINAL FAT PAD, MAMMARY GLAND, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    BROWN ADIPOSE TISSUE, HET, Male, WTSI
endocrine system (2)
  • Ptges2tm1a(EUCOMM)Wtsi
    ADRENAL GLAND, HET, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    TRACHEA, PARATHYROID GLAND, THYROID GLAND, HET, Female, WTSI
reproductive system (2)
  • Ptges2tm1a(EUCOMM)Wtsi
    OVIDUCT, OVARY, UTERUS, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
respiratory system (2)
  • Ptges2tm1a(EUCOMM)Wtsi
    TRACHEA, PARATHYROID GLAND, THYROID GLAND, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    LUNG, HET, Male, WTSI
set of connective tissues (2)
  • Ptges2tm1a(EUCOMM)Wtsi
    INGUINAL FAT PAD, MAMMARY GLAND, HET, Female, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    BROWN ADIPOSE TISSUE, HET, Male, WTSI
urinary system (2)
  • Ptges2tm1a(EUCOMM)Wtsi
    LOWER URINARY TRACT, HET, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    KIDNEY, HET, Female, WTSI
exocrine system (1)
  • Ptges2tm1a(EUCOMM)Wtsi
    INGUINAL FAT PAD, MAMMARY GLAND, HET, Female, WTSI
musculoskeletal system (1)
  • Ptges2tm1a(EUCOMM)Wtsi
    BONE, HET, Male, WTSI
sensory organ (1)
  • Ptges2tm1a(EUCOMM)Wtsi
    EYE, HET, Male, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (80)
  • Ptges2tm1a(EUCOMM)Wtsi
    TRUNK, WT, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    TRUNK, WT, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    HEAD, WT, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    HEAD, WT, Male, WTSI
  • Ptges2tm1a(EUCOMM)Wtsi
    LOWER ARM, WT, Male, WTSI

show all 80 images

Skin Histopathology (1)
  • Ptges2tm1a(EUCOMM)Wtsi
    FOOT DIGIT 4, HOM, Female, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ptges2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ptges2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Ptges2tm3a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ptges2tm96746(L1L2_Pgk_P)
Vector
Gene