Gene: Ppil3

Order

Name peptidylprolyl isomerase (cyclophilin)-like 3

Synonyms
  • 2510026K04Rik
  • 2310076N22Rik
  • Cyp10l

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1917475    Ensembl Gene    Ensembl Orthologs    My Genes   

Phenotype associations for Ppil3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ppil3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased circulating cholesterol level Ppil3tm1b(EUCOMM)Wtsi HOM Male postnatal 1.53E-7
absent pinna reflex Ppil3tm1b(EUCOMM)Wtsi HOM Male postnatal 8.6E-7
decreased circulating HDL cholesterol level Ppil3tm1b(EUCOMM)Wtsi HOM Female postnatal 1.34E-6
increased circulating HDL cholesterol level Ppil3tm1b(EUCOMM)Wtsi HOM Male postnatal 1.34E-6
increased circulating free fatty acid level Ppil3tm1b(EUCOMM)Wtsi HOM Male postnatal 1.28E-5
abnormal bone structure Ppil3tm1b(EUCOMM)Wtsi HOM Female Male postnatal 4.99E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No
Blood vessel 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse nervous system reproductive system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (2)
  • Ppil3tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Ppil3tm1b(EUCOMM)Wtsi
    brain, HET, Female, WTSI
nervous system (1)
  • Ppil3tm1b(EUCOMM)Wtsi
    brain, HET, Female, WTSI
reproductive system (1)
  • Ppil3tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
trunk (1)
  • Ppil3tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • X-ray: XRay Images Dorso Ventral
    42 Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Forepaw
    14 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • Anti-nuclear antibody assay
    6 Images
  • Eye Morphology: Images Slit Lamp
    1 Images
  • Eye Morphology: Images Ophthalmoscopy
    2 Images
Legacy Phenotype Associated Images
Xray (70)
  • Ppil3tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Ppil3tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Ppil3tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Ppil3tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
  • Ppil3tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI

show all 70 images

Eye Morphology (3)
  • Ppil3tm1b(EUCOMM)Wtsi
    abnormal retinal pigmentation, HOM, Male, WTSI
  • Ppil3tm1b(EUCOMM)Wtsi
    abnormal cornea morphology, HOM, Female, WTSI
  • Ppil3tm1b(EUCOMM)Wtsi
    abnormal retinal pigmentation, HOM, Male, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ppil3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ppil3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene