Gene: Tatdn3

Order

Name TatD DNase domain containing 3

Synonyms 1500010M24Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1916222    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Tatdn3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Tatdn3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased bone mineral density Tatdn3tm1b(EUCOMM)Wtsi HOM Male postnatal 4.49E-5
decreased blood urea nitrogen level Tatdn3tm1a(EUCOMM)Wtsi HOM Female postnatal 6.37E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No
Aorta 4 No (1/562) (2/4)
Blood vessel 4 No
Bone 4 No (1/539)
Brain 4 No (6/562) (4/4)
Brainstem 4 No (4/562)
Brown adipose tissue 4 No
Cartilage tissue 4 No (1/562)
Cerebellum 4 No (4/562)
Cerebral cortex 4 No (5/562)
Eye 4 No (1/562)
Gall bladder 4 No
Heart 4 No (3/562) (2/4)
Hippocampus 4 No (5/562)
Hypothalamus 4 No (4/562)
Kidney 4 No (20/562) (1/4)
Large intestine 4 No (12/562)
Liver 4 No
Lower urinary tract 4 No (3/562)
Lung 4 No (3/562)
Lymph node 4 No (1/562)
Mammary gland 4 No
Esophagus 4 No
Olfactory lobe 4 No
Ovary 4 No (1/562)
Oviduct 4 No (2/562) (1/4)
Pancreas 4 No (6/562)
Parathyroid gland 4 No (2/540)
Peripheral nervous system 4 No (3/562) (2/4)
Peyer's patch 4 No
Pituitary gland 4 No (1/562)
Prostate gland 4 No (5/562)
Skeletal muscle tissue 4 No
Skin 4 No (1/562)
Small intestine 4 No (11/562)
Spinal cord 4 No (3/562) (2/4)
Spleen 4 No (4/562)
Stomach 4 No (9/562)
Striatum 4 No (4/562)
Testis 4 No (4/562) (1/4)
Thymus 4 No
Thyroid gland 4 No (16/562)
Trachea 4 No (3/562)
Uterus 4 No (2/562) (1/4)
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse cardiovascular system nervous system reproductive system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
trunk (5)
  • Tatdn3tm1a(EUCOMM)Wtsi
    OVIDUCT, HET, Female, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    AORTA, HET, Female, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    SPINAL CORD, HET, Female, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    KIDNEY, HET, Male, WTSI
nervous system (4)
  • Tatdn3tm1a(EUCOMM)Wtsi
    PERIPHERAL NERVOUS SYSTEM, TRIGEMINAL V NERVE, HET, Female, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    BRAIN, HET, Male, WTSI
  • Tatdn3tm1b(EUCOMM)Wtsi
    BRAIN, HET, Female, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    SPINAL CORD, HET, Female, WTSI
reproductive system (2)
  • Tatdn3tm1a(EUCOMM)Wtsi
    OVIDUCT, HET, Female, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    TESTIS, HET, Male, WTSI
cardiovascular system (1)
  • Tatdn3tm1a(EUCOMM)Wtsi
    AORTA, HET, Female, WTSI
urinary system (1)
  • Tatdn3tm1a(EUCOMM)Wtsi
    KIDNEY, HET, Male, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    55 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    25 Images
  • X-ray: XRay Images Forepaw
    25 Images
  • X-ray: XRay Images Skull Lateral Orientation
    25 Images
  • X-ray: XRay Images Dorso Ventral
    79 Images
  • Eye Morphology: Images Ophthalmoscopy
    1 Images
  • Eye Morphology: Images Slit Lamp
    2 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
  • Ear epidermis immunophenotyping
    12 Images
Legacy Phenotype Associated Images
Xray (134)
  • Tatdn3tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Tatdn3tm1a(EUCOMM)Wtsi
    HOM, Female, WTSI

show all 134 images

Brain Histopathology (8)
  • Tatdn3tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Tatdn3tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI
  • Tatdn3tm1b(EUCOMM)Wtsi
    HIPPOCAMPUS PYRAMIDAL LAYER, decreased hippocampus pyramidal cell length, HOM, Male, WTSI
  • Tatdn3tm1b(EUCOMM)Wtsi
    decreased hippocampus pyramidal cell length, HIPPOCAMPUS PYRAMIDAL LAYER, HOM, Male, WTSI
  • Tatdn3tm1b(EUCOMM)Wtsi
    HOM, Male, WTSI

show all 8 images

Eye Morphology (3)
  • Tatdn3tm1a(EUCOMM)Wtsi
    cornea/lens fusion, HOM, Female, WTSI
  • Tatdn3tm1b(EUCOMM)Wtsi
    abnormal retinal pigmentation, HOM, Male, WTSI
  • Tatdn3tm1b(EUCOMM)Wtsi
    LEFT EYE, HOM, Male, WTSI
Anti-nuclear Antibody Assay (1)
  • Tatdn3tm1b(EUCOMM)Wtsi
    HOM, Female, WTSI
Histology Slide (1)
  • Tatdn3tm1a(EUCOMM)Wtsi
    HET, Unsexed, WTSI

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Tatdn3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Tatdn3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene