Gene: Pygo2

Order

Name pygopus 2

Synonyms
  • 1190004M21Rik
  • mpygo2

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1916161    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Pygo2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Pygo2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal craniofacial morphology Pygo2tm1b(EUCOMM)Wtsi HOM Female embryonic day 15.5 0.0
abnormal eye morphology Pygo2tm1b(EUCOMM)Wtsi HOM Male embryonic day 12.5 0.0
abnormal hindbrain morphology Pygo2tm1b(EUCOMM)Wtsi HOM Male embryonic day 12.5 0.0
abnormal kidney morphology Pygo2tm1b(EUCOMM)Wtsi HET Female postnatal 0.0
abnormal midbrain morphology Pygo2tm1b(EUCOMM)Wtsi HOM Male embryonic day 12.5 0.0
abnormal neural tube closure Pygo2tm1b(EUCOMM)Wtsi HOM Male embryonic day 12.5 0.0
abnormal seminal vesicle morphology Pygo2tm1b(EUCOMM)Wtsi HET Male postnatal 0.0
edema Pygo2tm1b(EUCOMM)Wtsi HOM Female Male embryonic day 15.5 0.0
hydrometra Pygo2tm1b(EUCOMM)Wtsi HET Female postnatal 0.0
preweaning lethality, complete penetrance Pygo2tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
small superior vagus ganglion Pygo2tm1b(EUCOMM)Wtsi HET Female postnatal 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No (1/2)
Cartilage tissue 2 No
Cecum 2 No (12/383) (1/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (2/2)
Diaphragm 2 No (2/2)
Duodenum 2 No (2/127)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Gall bladder 2 No
Gonadal fat pad 2 No (1/2)
Harderian gland 2 No (2/2)
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (2/2)
Jejunum 2 No (6/127) (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No (1/2)
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No (1/2)
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No
Parotid gland 2 No (2/2)
Penis 2 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Quadriceps 2 No (2/2)
Sciatic nerve 2 No (1/2)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No (2/2)
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127) (2/2)
Trachea 2 No (2/2)
Trigeminal V nerve 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vagina 2 No (1/2)
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system limb digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Gross Morphology Embryo E14.5-E15.5
    24 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Pygo2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue
Pygo2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Pygo2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Pygo2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene