Gene: Rab3gap2

Order

Name RAB3 GTPase activating protein subunit 2

Synonyms 1110059F07Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1916043    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Rab3gap2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rab3gap2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased bone mineral density Rab3gap2tm1b(KOMP)Wtsi HOM Female Male postnatal 2.3E-8
hyperactivity Rab3gap2tm1b(KOMP)Wtsi HOM Female Male postnatal 2.65E-8
decreased heart rate Rab3gap2tm1b(KOMP)Wtsi HOM Female Male postnatal 1.2E-7
prolonged RR interval Rab3gap2tm1b(KOMP)Wtsi HOM Female Male postnatal 1.3E-7
decreased body length Rab3gap2tm1b(KOMP)Wtsi HOM Female Male postnatal 2.2E-7
decreased bone mineral content Rab3gap2tm1b(KOMP)Wtsi HOM Female Male postnatal 3.4E-6
decreased lean body mass Rab3gap2tm1b(KOMP)Wtsi HOM Female Male postnatal 3.94E-6
increased circulating bilirubin level Rab3gap2tm1b(KOMP)Wtsi HOM Female Male postnatal 4.69E-6
decreased total body fat amount Rab3gap2tm1b(KOMP)Wtsi HOM Female Male postnatal 5.45E-6
abnormal behavior Rab3gap2tm1b(KOMP)Wtsi HOM Female Male postnatal 1.08E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562) (2/2)
Brain 2 No (6/562)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No (4/393)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562)
Urinary bladder 2 No
Uterus 2 No (2/562)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    reproductive system
    exocrine system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/440)
Dorsal root ganglion 1 (1/3)
Ear 1 (1/440)
Embryo 1 (1/440)
Eye 1 (1/440)
Foot 1
Forebrain 1 (1/440)
Forelimb 1 (1/440)
Fronto-nasal process 1 (1/4)
Hand 1
Head 1 (5/440)
Heart 1 (1/440)
Hindbrain 1 (5/440)
Hindlimb 1 (1/440)
Liver 1 (1/440)
Lung 1 (1/440)
Mandibular process 1 (1/440)
Maxillary process 1 (1/440)
Midbrain 1 (1/440)
Nose 1 (1/5)
Oral cavity 1 (1/440)
Skin 1 (1/440)
Spinal cord 1 (1/4)
Tail 1 (1/440)
Tail somite 1 (1/440)


Associated Images

Associated Images
  • Electroretinography 2: Rod and cone PDF
    2 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rab3gap2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Rab3gap2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene