Gene: Zwilch

Order

Name zwilch kinetochore protein

Synonyms 2310031L18Rik

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1915264    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Zwilch

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Zwilch data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Zwilchtm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
abnormal embryo size Zwilchtm1.1(KOMP)Vlcg HET Male embryonic day 12.5 0.0
abnormal embryo size Zwilchtm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
abnormal placenta morphology Zwilchtm1.1(KOMP)Vlcg HOM Male embryonic day 12.5 0.0
abnormal placenta size Zwilchtm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
abnormal placenta vasculature Zwilchtm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
abnormal tail morphology Zwilchtm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
edema Zwilchtm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0
embryonic growth retardation Zwilchtm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
embryonic growth retardation Zwilchtm1.1(KOMP)Vlcg HET Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Zwilchtm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
syndactyly Zwilchtm1.1(KOMP)Vlcg HOM Female Male embryonic day 15.5 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Bone marrow 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Heart 2 No
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (1/2)
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No (2/2)
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No (2/2)
Pituitary gland 2 No (1/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584)
Trachea 2 No (1/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/3)
Dorsal root ganglion 2 (1/47) Image Only
Ear 2 (1/485) (2/3)
Embryo 2 (1/485) (2/3)
Eye 2 (1/485) (2/3)
Foot 2 (1/485) (2/3)
Forebrain 2 (1/485) (2/3)
Forelimb 2 (1/485) (2/3)
Fronto-nasal process 2 (1/48) Image Only
Hand 2 (1/485) (2/3)
Head 2 (5/485) (2/3)
Heart 2 (1/485) (2/3)
Hindbrain 2 (6/485) (2/3)
Hindlimb 2 (1/485) (2/3)
Liver 2 (1/485) (2/3)
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (2/3)
Maxillary process 2 (1/485) (2/3)
Midbrain 2 (1/485) (2/3)
Nose 2 (1/51) (2/3)
Oral cavity 2 (1/485) Image Only
Skin 2 (1/485) (2/3)
Spinal cord 2 (1/50) (2/3)
Tail 2 (1/485) (2/3)
Tail somite 2 (1/485) Image Only


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    6 Images
  • X-ray: XRay Images Lateral Orientation
    6 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    6 Images
  • Gross Morphology Embryo E12.5
    6 Images
  • X-ray: XRay Images Skull Lateral Orientation
    6 Images
  • X-ray: XRay Images Forepaw
    6 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • Gross Morphology Embryo E14.5-E15.5
    5 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Zwilchtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Zwilchtm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Zwilchtm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Zwilchtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene