Gene: Bzw2

Order

Name basic leucine zipper and W2 domains 2

Synonyms
  • 1110001I24Rik
  • HSPC028

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1914162    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Bzw2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Bzw2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased circulating glucose level Bzw2tm1b(KOMP)Mbp HOM Male postnatal 3.82E-9
increased circulating glucose level Bzw2tm1b(KOMP)Mbp HOM Female postnatal 3.82E-9
increased bone mineral density Bzw2tm1b(KOMP)Mbp HOM Female Male postnatal 1.18E-8
increased lean body mass Bzw2tm1b(KOMP)Mbp HOM Female Male postnatal 1.92E-8
increased bone mineral content Bzw2tm1b(KOMP)Mbp HOM Female Male postnatal 1.75E-7
shortened RR interval Bzw2tm1b(KOMP)Mbp HOM Female Male postnatal 1.49E-5
decreased total body fat amount Bzw2tm1b(KOMP)Mbp HOM Female Male postnatal 1.56E-5
abnormal bone structure Bzw2tm1b(KOMP)Mbp HOM Female Male postnatal 1.66E-5
increased circulating alkaline phosphatase level Bzw2tm1b(KOMP)Mbp HOM Female Male postnatal 2.54E-5
cardiovascular system phenotype Bzw2tm1b(KOMP)Mbp HOM Female Male postnatal 3.41E-5
increased body length Bzw2tm1b(KOMP)Mbp HOM Female Male postnatal 5.88E-5
abnormal sleep behavior Bzw2tm1b(KOMP)Mbp HOM Female Male postnatal 8.34E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (1/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (1/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system trunk postnatal mouse nervous system sensory organ immune system exocrine system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/485)
Ear 1 (1/485)
Embryo 1 (1/485) (1/2)
Eye 1 (1/485) (1/2)
Foot 1 (1/485) (1/2)
Forebrain 1 (1/485)
Forelimb 1 (1/485) (1/2)
Hand 1 (1/485)
Head 1 (5/485) (1/2)
Heart 1 (1/485)
Hindbrain 1 (6/485)
Hindlimb 1 (1/485) (1/2)
Liver 1 (1/485)
Lung 1 (1/485)
Mandibular process 1 (1/485) (1/2)
Maxillary process 1 (1/485) (1/2)
Midbrain 1 (1/485)
Oral cavity 1 (1/485)
Skin 1 (1/485)
Tail 1 (1/485) (1/2)
Tail somite 1 (1/485)
Umbilical artery embryonic part 1 (1/47) (1/1)
Umbilical vein embryonic part 1 (1/47) (1/1)


Associated Images

Associated Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    16 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Forepaw
    10 Images
  • Sleep Wake: Wake state (bmp file)
    16 Images
  • Electroretinography: Rod waveform (pdf format)
    4 Images
  • Electroretinography: Cone waveform (pdf format)
    4 Images
  • Combined SHIRPA and Dysmorphology
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Bzw2tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Bzw2tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre)
Vector
Gene