Gene: Timm50

Order

Name translocase of inner mitochondrial membrane 50

Synonyms
  • 2810403L02Rik
  • TIM50L

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1913775    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Timm50

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Timm50 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Timm50tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
increased heart weight Timm50tm1b(EUCOMM)Wtsi HET Female Male postnatal 3.65E-5
decreased total body fat amount Timm50tm1b(EUCOMM)Wtsi HET Male postnatal 7.9E-5
abnormal retinal inner nuclear layer morphology Timm50tm1b(EUCOMM)Wtsi HET Female Male postnatal 8.07E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3 (6/485) (3/3)
Ear 3 (1/485) (3/3)
Embryo 3 (1/485) (3/3)
Eye 3 (1/485) (3/3)
Foot 3 (1/485) (3/3)
Forebrain 3 (1/485) (3/3)
Forelimb 3 (1/485) (3/3)
Hand 3 (1/485) (3/3)
Head 3 (5/485) (3/3)
Heart 3 (1/485) (3/3)
Hindbrain 3 (6/485) (3/3)
Hindlimb 3 (1/485) (3/3)
Liver 3 (1/485) (3/3)
Lung 3 (1/485) (3/3)
Mandibular process 3 (1/485) (3/3)
Maxillary process 3 (1/485) (3/3)
Midbrain 3 (1/485) (3/3)
Oral cavity 3 (1/485) (3/3)
2 (7/25) (2/2)
Skin 3 (1/485) (3/3)
Tail 3 (1/485) (3/3)
Tail somite 3 (1/485) (3/3)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images section
    2 Images
  • Echo: M-Mode Images
    14 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • Embryo LacZ: LacZ images wholemount
    1 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Timm50tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Timm50tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Timm50tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene