Gene: Rab11a

Order

Name RAB11A, member RAS oncogene family

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1858202    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Rab11a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rab11a data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Rab11atm1b(KOMP)Wtsi HET Female embryonic day 9.5 0.0
abnormal embryo turning Rab11atm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
embryonic growth retardation Rab11atm1b(KOMP)Wtsi HET Female Male embryonic day 9.5 0.0
embryonic lethality prior to organogenesis Rab11atm1b(KOMP)Wtsi HOM Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Rab11atm1b(KOMP)Wtsi HOM Female Male n/a 0.0
persistence of hyaloid vascular system Rab11atm1b(KOMP)Wtsi HET Female Male postnatal 5.87E-6
thrombocytopenia Rab11atm1b(KOMP)Wtsi HET Male postnatal 3.88E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (1/2)
Aorta 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Epididymis 2 No (18/134)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (1/2)
Heart 2 No (1/2)
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (1/2)
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Urinary bladder 2 No
Uterus 2 No (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    digestive system
    cardiovascular system
    sensory organ
    reproductive system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (1/2)
Dorsal root ganglion 1 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485) (2/2)
Eye 2 (1/485)
Foot 2 (1/485) (1/2)
Forebrain 2 (1/485)
Forelimb 2 (1/485) (1/2)
Fronto-nasal process 1 (1/48)
Hand 2 (1/485) (1/2)
Head 2 (5/485) (1/2)
Heart 2 (1/485) (1/2)
Hindbrain 2 (6/485) (1/2)
Hindlimb 2 (1/485) (1/2)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485) (1/2)
Maxillary process 2 (1/485)
Midbrain 2 (1/485)
Nose 1 (1/51)
Oral cavity 2 (1/485)
Skin 2 (1/485)
Spinal cord 1 (1/50)
Tail 2 (1/485) (1/2)
Tail somite 2 (1/485)
Umbilical artery embryonic part 1 (1/47) (1/1)
Umbilical vein embryonic part 1 (1/47) (1/1)


Associated Images

Associated Images
  • X-ray: XRay Images Skull Lateral Orientation
    9 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • X-ray: XRay Images Lateral Orientation
    9 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    9 Images
  • X-ray: XRay Images Forepaw
    9 Images
  • X-ray: XRay Images Dorso Ventral
    9 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rab11atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Rab11atm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene