Gene: Exosc9

Order

Name exosome component 9

Synonyms
  • PM/Scl-75
  • p6
  • Pmscl1
  • p5
  • RRP45

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1355319    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Exosc9

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Exosc9 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, complete penetrance Exosc9tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
decreased circulating fructosamine level Exosc9tm1b(EUCOMM)Wtsi HET Female Male postnatal 3.35E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (1/2)
Aorta 2 No (1/2)
Blood vessel 2 No
Bone 2 No (1/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Eye 2 No
Gall bladder 2 No
Heart 2 No (1/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (1/2)
Lymph node 2 No
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle tissue 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No (1/2)
Uterus 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse endocrine system respiratory system cardiovascular system nervous system set of connective tissues reproductive system musculoskeletal system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (13)
  • Exosc9tm1b(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    heart, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    parathyroid gland, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    peripheral nervous system, trigeminal V nerve, HET, Female, WTSI

show all 13 images

trunk (10)
  • Exosc9tm1b(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    heart, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    bone, rib, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    kidney, HET, Female, WTSI

show all 10 images

nervous system (3)
  • Exosc9tm1b(EUCOMM)Wtsi
    spinal cord, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    peripheral nervous system, trigeminal V nerve, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    striatum, HET, Female, WTSI
endocrine system (2)
  • Exosc9tm1b(EUCOMM)Wtsi
    parathyroid gland, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    adrenal gland, HET, Female, WTSI
reproductive system (2)
  • Exosc9tm1b(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    uterus, HET, Female, WTSI
urinary system (2)
  • Exosc9tm1b(EUCOMM)Wtsi
    urinary bladder, lower urinary tract, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
cardiovascular system (1)
  • Exosc9tm1b(EUCOMM)Wtsi
    heart, HET, Female, WTSI
immune system (1)
  • Exosc9tm1b(EUCOMM)Wtsi
    thymus, HET, Female, WTSI
musculoskeletal system (1)
  • Exosc9tm1b(EUCOMM)Wtsi
    bone, rib, HET, Female, WTSI
respiratory system (1)
  • Exosc9tm1b(EUCOMM)Wtsi
    lung, HET, Female, WTSI

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Forepaw
    13 Images
  • X-ray: XRay Images Dorso Ventral
    40 Images
  • Eye Morphology: Images Ophthalmoscopy
    2 Images
  • Eye Morphology: Images Slit Lamp
    2 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    13 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • Anti-nuclear antibody assay
    6 Images
  • DSS Histology
    8 Images
Legacy Phenotype Associated Images
Xray (108)
  • Exosc9tm1b(EUCOMM)Wtsi
    HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    HET, Female, WTSI

show all 108 images

Histology Slide (8)
  • Exosc9tm1b(EUCOMM)Wtsi
    TS20 chorioallantoic placenta, TS20 chorioallantoic placenta, HET, Male, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    TS20 liver, HET, Male, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    TS20 midbrain, HET, Male, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    TS20 skin, HET, Male, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    TS20 eye, HET, Male, WTSI

show all 8 images

Eye Morphology (4)
  • Exosc9tm1b(EUCOMM)Wtsi
    corneal opacity, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    abnormal retinal pigmentation, HET, Male, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    fused cornea and lens, HET, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    abnormal retinal pigmentation, HET, Female, WTSI
Dysmorphology (2)
  • Exosc9tm1b(EUCOMM)Wtsi
    tail, abnormal tail morphology, WT, Female, WTSI
  • Exosc9tm1b(EUCOMM)Wtsi
    polydactylous syndactyly, WT, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Exosc9tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Exosc9tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene