Gene: Slc25a3

Order

Name solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3

Synonyms
  • Phc
  • 5730556H19Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1353498    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Slc25a3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Slc25a3 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal allantois morphology Slc25a3tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal embryo turning Slc25a3tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal heart looping Slc25a3tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal heart morphology Slc25a3tm1b(EUCOMM)Wtsi HET Male postnatal 0.0
abnormal limb bud morphology Slc25a3tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal neural tube closure Slc25a3tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal neural tube morphology Slc25a3tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal pharyngeal arch morphology Slc25a3tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal tail bud morphology Slc25a3tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
embryonic lethality prior to organogenesis Slc25a3tm1b(EUCOMM)Wtsi HOM Female Male embryonic day 9.5 0.0
enlarged heart Slc25a3tm1b(EUCOMM)Wtsi HET Male postnatal 0.0
pale yolk sac Slc25a3tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
pallor Slc25a3tm1b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Slc25a3tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
small testis Slc25a3tm1b(EUCOMM)Wtsi HET Male postnatal 0.0
increased circulating serum albumin level Slc25a3tm1b(EUCOMM)Wtsi HET Male postnatal 5.28E-6
increased blood urea nitrogen level Slc25a3tm1b(EUCOMM)Wtsi HET Male postnatal 1.87E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (1/2)
Aorta 2 No
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383) (1/2)
Cerebellum 2 No
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (1/2)
Diaphragm 2 No
Duodenum 2 No (2/127) (1/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No
Gall bladder 2 No
Gonadal fat pad 2 No
Harderian gland 2 No (1/2)
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (1/2)
Jejunum 2 No (6/127)
Kidney 2 No (18/584) (1/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No (1/2)
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (1/2)
Parathyroid gland 2 No (1/2)
Parotid gland 2 No (1/2)
Penis 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (1/2)
Prostate gland 2 No (12/584) (1/2)
Quadriceps 2 No
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (1/2)
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584) (1/2)
Stomach 2 No (12/584) (1/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No (1/2)
Submandibular gland 2 No (2/132) (1/2)
Testis 2 No (2/584)
Thymus 2 No (1/2)
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127) (1/2)
Trachea 2 No (1/2)
Trigeminal V nerve 2 No
Urinary bladder 2 No (1/2)
Uterus 2 No (1/2)
Vagina 2 No (1/2)
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse endocrine system respiratory system digestive system nervous system sensory organ reproductive system immune system exocrine system integumental system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 8 (1/47) (8/8)
Axial skeleton 8 (1/51) (8/8)
Brain 8 (6/485)
Central nervous system ganglion 8 (1/51) (2/8)
Dorsal root ganglion 8 (1/47)
Ear 8 (1/485)
Embryo 8 (1/485) (8/8)
Outer ear 8 (1/47)
Eye 8 (1/485) (7/8)
Femur pre-cartilage condensation 5 (1/46) (3/5)
Foot 8 (1/485)
Forearm 8 (1/282) (7/8)
Forebrain 8 (1/485)
Forelimb 8 (1/485) (7/8)
Fronto-nasal process 8 (1/48) (5/8)
Gut 7 (1/50) (5/7)
Hand 8 (1/485)
Head 8 (5/485) (6/8)
Head mesenchyme 8 (1/47) (6/8)
Heart 8 (1/485) (8/8)
Heart ventricle 8 (1/47) (6/8)
Hindbrain 8 (6/485)
Hindlimb 8 (1/485) (5/8)
Humerus pre-cartilage condensation 5 (1/46) (3/5)
Inner ear 5 (1/46)
Intestine 8 (1/47) (6/8)
Liver 8 (1/485)
Lower leg 8 (1/282) (2/8)
Lung 8 (1/485) (1/8)
Mandibular process 8 (1/485) (5/8)
Maxillary process 8 (1/485) (5/8)
Meckel's cartilage 8 (5/8)
Midbrain 8 (1/485)
Nasal septum 8 (1/47)
Nose 8 (1/51) (5/8)
Notochord 8 (1/47) (3/8)
Oral cavity 8 (1/485) (5/8)
Outflow tract 8 (1/47) (8/8)
8 (7/25)
Radius-ulna pre-cartilage condensation 8 (1/46) (7/8)
Rib pre-cartilage condensation 2 (1/46)
Skeleton 8 (1/51)
Skin 8 (1/485)
Spinal cord 8 (1/50)
Tail 8 (1/485) (1/8)
Tail somite 8 (1/485) (3/8)
Thoracic vertebral cartilage condensation 3 (1/46)
Tongue 5 (1/46)
Trunk mesenchyme 8 (1/47) (5/8)
Umbilical artery embryonic part 8 (1/47) (7/8)
Umbilical vein embryonic part 8 (1/47) (7/8)
Upper arm 8 (1/282) (5/8)
Upper leg 8 (1/282) (5/8)
Vibrissa 8 (1/47)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    20 Images
  • X-ray: XRay Images Dorso Ventral
    40 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Slc25a3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Slc25a3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue
Slc25a3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene