Gene: Cops7a

Order

Name COP9 signalosome subunit 7A

Synonyms
  • D6Ertd35e
  • COP9 complex S7a

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1349400    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Cops7a

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cops7a data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal eye morphology Cops7atm1b(KOMP)Mbp HOM Female Male postnatal 0.0
abnormal heart morphology Cops7atm1b(KOMP)Mbp HOM Female Male postnatal 0.0
abnormal heart shape Cops7atm1b(KOMP)Mbp HOM Male postnatal 0.0
abnormal seminal vesicle morphology Cops7atm1b(KOMP)Mbp HOM Male postnatal 0.0
abnormal spleen morphology Cops7atm1b(KOMP)Mbp HOM Male postnatal 0.0
abnormal thymus morphology Cops7atm1b(KOMP)Mbp HOM Male postnatal 0.0
abnormal urinary bladder morphology Cops7atm1b(KOMP)Mbp HOM Male postnatal 0.0
enlarged heart Cops7atm1b(KOMP)Mbp HOM Female Male postnatal 0.0
hydrometra Cops7atm1b(KOMP)Mbp HOM Female postnatal 0.0
male infertility Cops7atm1b(KOMP)Mbp HOM Male postpartum stage 0.0
small seminal vesicle Cops7atm1b(KOMP)Mbp HOM Male postnatal 0.0
small spleen Cops7atm1b(KOMP)Mbp HOM Male postnatal 0.0
small superior vagus ganglion Cops7atm1b(KOMP)Mbp HOM Female postnatal 0.0
small thymus Cops7atm1b(KOMP)Mbp HOM Male postnatal 0.0
improved glucose tolerance Cops7atm1b(KOMP)Mbp HOM Male postnatal 1.75E-6
decreased prepulse inhibition Cops7atm1b(KOMP)Mbp HOM Female Male postnatal 2.17E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No (1/2)
Cartilage tissue 2 No
Cecum 2 No (12/383) (2/2)
Cerebellum 2 No (1/2)
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (2/2)
Diaphragm 2 No (1/2)
Duodenum 2 No (2/127) (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (1/2)
Eye 2 No (2/2)
Gall bladder 2 No
Gonadal fat pad 2 No (1/2)
Harderian gland 2 No (2/2)
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (2/2)
Jejunum 2 No (6/127)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No (2/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (1/2)
Ovary 2 No (1/584)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Parotid gland 2 No
Penis 2 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584) (1/2)
Quadriceps 2 No (1/2)
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127) (1/2)
Trachea 2 No (1/2)
Trigeminal V nerve 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vagina 2 No
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system adipose tissue musculoskeletal system trunk postnatal mouse nervous system sensory organ exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    11 Images
  • X-ray: XRay Images Lateral Orientation
    9 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cops7atm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue
Cops7atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Cops7atm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene