Gene: Esrra

Order

Name estrogen related receptor, alpha

Synonyms
  • ERRalpha
  • Err1
  • Estrra
  • Nr3b1

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1346831    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Esrra

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Esrra data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased body length Esrratm1.1(KOMP)Vlcg HOM Female Male postnatal 7.71E-13
decreased lean body mass Esrratm1.1(KOMP)Vlcg HOM Female Male postnatal 4.27E-12
decreased total body fat amount Esrratm1.1(KOMP)Vlcg HOM Female Male postnatal 4.87E-9
increased startle reflex Esrratm1.1(KOMP)Vlcg HOM Female Male postnatal 1.19E-8
increased bone mineral content Esrratm1.1(KOMP)Vlcg HOM Female Male postnatal 1.03E-5
increased grip strength Esrratm1.1(KOMP)Vlcg HOM Female Male postnatal 2.59E-5
prolonged QRS complex duration Esrratm1.1(KOMP)Vlcg HOM Female Male postnatal 2.8E-5
shortened PQ interval Esrratm1.1(KOMP)Vlcg HOM Female Male postnatal 3.89E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No (2/2)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No (2/2)
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No (2/2)
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/485) (2/3)
Dorsal root ganglion 1 (1/47) Image Only
Ear 2 (1/485)
Embryo 2 (1/485) (2/3)
Eye 2 (1/485) (2/3)
Foot 2 (1/485) (1/3)
Forebrain 2 (1/485) (1/3)
Forelimb 2 (1/485) (1/3)
Fronto-nasal process 1 (1/48) Image Only
Hand 2 (1/485) (1/3)
Head 2 (5/485) (2/3)
Heart 2 (1/485) (2/3)
Hindbrain 2 (6/485) (2/3)
Hindlimb 2 (1/485) (1/3)
Liver 2 (1/485)
Lung 2 (1/485) Image Only
Mandibular process 2 (1/485) (1/3)
Maxillary process 2 (1/485) (1/3)
Midbrain 2 (1/485) (2/3)
Nose 1 (1/51)
Oral cavity 2 (1/485)
Skin 2 (1/485) (2/3)
Spinal cord 1 (1/50) (1/1)
Tail 2 (1/485) (2/3)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    2 Images
  • X-ray: XRay Images Skull Lateral Orientation
    2 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    2 Images
  • X-ray: XRay Images Forepaw
    2 Images
  • X-ray: XRay Images Dorso Ventral
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Esrratm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Esrratm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Esrratm1(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Esrratm457105(L1L2_GT1_LF2A_LacZ_BetactP_neo)
Vector
Gene