Gene Summary
IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Mfap4 by phenotypic similarity.
Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.
Phenotype | Allele | Zygosity | Sex | Life Stage |
---|---|---|---|---|
Testis - MPATH pathological process term spermatogenesis defect | Mfap4tm1b(NCOM)Mfgc | HOM | Early adult | |
Testis - MPATH pathological process term dysplasia | Mfap4tm1b(NCOM)Mfgc | HOM | Early adult |
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Mfap4.
There are 2 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
Sexual Dimorphism of the Mouse Plasma Metabolome Is Associated with Phenotypes of 30 Gene Knockout Lines. | Metabolites (August 2023) | Mfap4tm1b(NCOM)Mfgc | PMC10456929 |
Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma. | NPJ systems biology and applications (May 2021) | Mfap4tm1b(NCOM)Mfgc | PMC8163790 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Mfap4tm1a(NCOM)Mfgc | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
Mfap4tm1b(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | Mice, Tissue |
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