Gene: Ndrg1

Order

Name N-myc downstream regulated gene 1

Synonyms
  • TDD5
  • Ndrl
  • CAP43
  • Tdd5
  • PROXY1
  • Ndr1
  • CMT4D
  • DRG1

Status ES CellsMice
tm2b
Mice
tm2a
phenotype data available

Links MGI:1341799    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Ndrg1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ndrg1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
decreased grip strength Ndrg1tm2b(KOMP)Wtsi HOM Female Male postnatal 5.88E-36
abnormal gait Ndrg1tm2b(KOMP)Wtsi HOM Female Male postnatal 2.03E-18
tremors Ndrg1tm2b(KOMP)Wtsi HOM Male postnatal 1.38E-13
decreased lean body mass Ndrg1tm2b(KOMP)Wtsi HOM Female Male postnatal 3.14E-9
decreased fasted circulating glucose level Ndrg1tm2b(KOMP)Wtsi HOM Female Male postnatal 3.25E-8
decreased bone mineral density Ndrg1tm2b(KOMP)Wtsi HOM Female Male postnatal 1.14E-7
decreased body length Ndrg1tm2b(KOMP)Wtsi HOM Female Male postnatal 1.56E-6
decreased bone mineral content Ndrg1tm2b(KOMP)Wtsi HOM Female postnatal 2.5E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (1/2)
Aorta 2 No
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383)
Cerebellum 2 No
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (1/2)
Diaphragm 2 No
Duodenum 2 No (2/127)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (1/2)
Eye 2 No (2/2)
Gall bladder 2 No
Gonadal fat pad 2 No
Harderian gland 2 No
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127)
Jejunum 2 No (6/127)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No
Midbrain 2 No (2/2)
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584) (1/2)
Parathyroid gland 2 No
Parotid gland 2 No
Penis 2 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Quadriceps 2 No (2/2)
Sciatic nerve 2 No (2/2)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (1/2)
Spleen 2 No (2/584) (1/2)
Stomach 2 No (12/584)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127) (2/2)
Trachea 2 No
Trigeminal V nerve 2 No (1/2)
Urinary bladder 2 No (2/2)
Uterus 2 No
Vagina 2 No (1/2)
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    limb respiratory system endocrine system digestive system reproductive system musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    8 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ndrg1tm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue
Ndrg1tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene