Gene: Parp1

Order

Name poly (ADP-ribose) polymerase family, member 1

Synonyms
  • PARP
  • sPARP-1
  • Adprt1
  • parp-1
  • Adprp
  • 5830444G22Rik

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1340806    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Parp1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Parp1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Parp1tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
decreased total retina thickness Parp1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.23E-8
abnormal retinal inner nuclear layer morphology Parp1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 1.35E-7
decreased grip strength Parp1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 5.12E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    12 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Parp1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Parp1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Parp1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene