Gene: Eya4

Order

Name EYA transcriptional coactivator and phosphatase 4

Synonyms B130023L16Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1337104    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Eya4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Eya4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Eya4tm1b(KOMP)Wtsi HOM embryonic day 15.5 0.0
edema Eya4tm1b(KOMP)Wtsi HET embryonic day 15.5 0.0
edema Eya4tm1b(KOMP)Wtsi HOM embryonic day 15.5 0.0
preweaning lethality, complete penetrance Eya4tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
small adrenal glands Eya4tm1b(KOMP)Wtsi HET Male postnatal 0.0
increased or absent threshold for auditory brainstem response Eya4tm1b(KOMP)Wtsi HET Female Male postnatal 1.56E-8

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Bone 1 No
Brain 2 No
Brainstem 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Esophagus 2 No (7/415)
Eye 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (1/2)
Large intestine 2 No (10/584) (1/2)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Trachea 2 No
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    postnatal mouse
    digestive system
    reproductive system
    exocrine system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 3 (1/51) (3/3)
Brain 3 (6/485)
Central nervous system ganglion 3 (1/51)
Ear 3 (1/485)
Embryo 3 (1/485) (3/5)
Eye 3 (1/485)
Foot 3 (1/485) (3/5)
Forebrain 3 (1/485)
Forelimb 3 (1/485) (3/5)
Gut 3 (1/50)
Hand 3 (1/485) (3/5)
Head 3 (5/485)
Heart 3 (1/485)
Hindbrain 3 (6/485)
Hindlimb 3 (1/485) (3/5)
Liver 3 (1/485)
Lung 3 (1/485)
Mandibular process 3 (1/485) (3/5)
Maxillary process 3 (1/485) (3/5)
Midbrain 3 (1/485)
Nose 3 (1/51) (3/3)
Oral cavity 3 (1/485)
Skeleton 3 (1/51) (3/3)
Skin 3 (1/485)
Spinal cord 3 (1/50)
Tail 3 (1/485) (3/5)
Tail somite 3 (1/485)
Trachea 3 (1/50)
Urinary system 3 (1/50)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • Adult LacZ: LacZ Images Section
    7 Images
  • X-ray: XRay Images Dorso Ventral
    14 Images
  • Gross Pathology and Tissue Collection
    9 Images
  • X-ray: XRay Images Hind Leg and Hip
    14 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Eya4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Eya4tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene