Gene: Wdr1

Order

Name WD repeat domain 1

Synonyms
  • Aip1
  • D5Wsu185e
  • rede

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1337100    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Wdr1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Wdr1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
embryonic lethality prior to organogenesis Wdr1tm1b(EUCOMM)Hmgu HOM Female Male embryonic day 9.5 0.0
preweaning lethality, complete penetrance Wdr1tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
decreased total body fat amount Wdr1tm1b(EUCOMM)Hmgu HET Male postnatal 2.0E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383)
Cerebellum 2 No
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No (2/2)
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Olfactory lobe 2 No
Oral epithelium 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Trigeminal V nerve 2 No
Urinary bladder 2 No (2/2)
Uterus 2 No
Vas deferens 2 No (15/388)
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse nervous system reproductive system trunk urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2 (1/47)
Axial skeleton 2 (1/51)
Brain 2 (6/485)
Central nervous system ganglion 2 (1/51)
Cranium 2 (1/46)
Dorsal root ganglion 2 (1/47)
Ear 2 (1/485)
Embryo 2 (1/485) (2/2)
Outer ear 2 (1/47)
Eye 2 (1/485)
Femur pre-cartilage condensation 2 (1/46)
Foot 2 (1/485)
Forearm 2 (1/282)
Forebrain 2 (1/485)
Forelimb 2 (1/485)
Fronto-nasal process 2 (1/48)
Gut 2 (1/50)
Hand 2 (1/485)
Head 2 (5/485)
Head mesenchyme 2 (1/47)
Heart 2 (1/485) (2/2)
Heart ventricle 2 (1/47)
Hindbrain 2 (6/485)
Hindlimb 2 (1/485)
Humerus pre-cartilage condensation 2 (1/46)
Inner ear 2 (1/46)
Intestine 2 (1/47)
Liver 2 (1/485)
Lower leg 2 (1/282)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485)
Mesonephros of female 2 (1/46)
Mesonephros of male 2 (1/46)
Metanephros 2 (1/46)
Midbrain 2 (1/485)
Nasal septum 2 (1/47)
Nose 2 (1/51)
Notochord 2 (1/47)
Oral cavity 2 (1/485)
Outflow tract 2 (1/47)
Pancreas 2 (1/46)
Pericardium 2 (1/46)
Pharynx 2 (1/46)
Radius-ulna pre-cartilage condensation 2 (1/46)
Rib pre-cartilage condensation 2 (1/46)
Skeleton 2 (1/51)
Skin 2 (1/485)
Spinal cord 2 (1/50)
Stomach 2 (1/46)
Tail 2 (1/485)
Tail somite 2 (1/485)
Thoracic vertebral cartilage condensation 2 (1/46)
Tongue 2 (1/46)
Trachea 2 (1/50)
Trunk mesenchyme 2 (1/47)
Umbilical artery embryonic part 2 (1/47) (2/2)
Umbilical vein embryonic part 2 (1/47)
Upper arm 2 (1/282)
Upper leg 2 (1/282)
Urinary system 2 (1/50)
Vibrissa 2 (1/47)


Associated Images

Phenotype associated images not available

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Wdr1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Wdr1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene