Gene: Prkab2

Order

Name protein kinase, AMP-activated, beta 2 non-catalytic subunit

Synonyms 5730553K21Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1336185    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Prkab2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Prkab2 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Prkab2tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
decreased mean platelet volume Prkab2tm1b(EUCOMM)Hmgu HET Male postnatal 9.09E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No (2/2)
Bone 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Gall bladder 2 No (2/2)
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Oral epithelium 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No (2/2)
Peripheral nervous system 2 No (2/2)
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Trachea 2 No
Uterus 2 No (1/2)
Vascular system 2 No (2/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    endocrine system
    digestive system
    cardiovascular system
    nervous system
    sensory organ
    reproductive system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1 (6/485) (2/2)
Ear 1 (1/485)
Embryo 1 (1/485) (2/2)
Eye 1 (1/485) (2/2)
Foot 1 (1/485)
Forebrain 1 (1/485) (2/2)
Forelimb 1 (1/485)
Hand 1 (1/485)
Head 1 (5/485) (2/2)
Heart 1 (1/485) (2/2)
Hindbrain 1 (6/485) (2/2)
Hindlimb 1 (1/485)
Liver 1 (1/485)
Lung 1 (1/485)
Mandibular process 1 (1/485)
Maxillary process 1 (1/485)
Midbrain 1 (1/485) (2/2)
Oral cavity 1 (1/485)
Skin 1 (1/485)
Tail 1 (1/485) (1/2)
Tail somite 1 (1/485)


Associated Images

Associated Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    3 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    10 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images
  • Adult LacZ: LacZ Images Wholemount
    18 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Prkab2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Prkab2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Prkab2tm1(NCOM)Cmhd Reporter-tagged deletion allele (with selection cassette)
Vector
Gene