Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Ran.
There are 4 publications which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
Ranbp1 modulates morphogenesis of the craniofacial midline in mouse models of 22q11.2 deletion syndrome. | Human molecular genetics (June 2023) | Ranbp1 tm1a(KOMP)Wtsi | PMC10244217 |
Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma. | Developmental cell (January 2023) | Rangap1tm1a(KOMP)Wtsi | 36696903 |
Critical reappraisal of mechanistic links of copy number variants to dimensional constructs of neuropsychiatric disorders in mouse models. | Psychiatry and clinical neurosciences (March 2018) | Ranbp1tm1b(KOMP)Wtsi | 29369447 |
An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo. | The Journal of clinical investigation (February 2014) | Ranbp9tm1c(EUCOMM)Hmgu | PMC3934164 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Rantm441723(L1L2_GT1_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors |
Rantm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
Rantm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
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