Gene: Hipk2

Name homeodomain interacting protein kinase 2

Synonyms
  • B230339E18Rik
  • 1110014O20Rik
  • Stank

Status ES CellsMice
tm2a
Mice
tm2b
phenotype data available

Links MGI:1314872   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Subviable

Phenotype associations for Hipk2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Hipk2 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Hipk2tm2b(EUCOMM)Hmgu HOM Female Male n/a 0.0
increased kidney weight Hipk2tm2b(EUCOMM)Hmgu HET Female Male postnatal 3.05E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (5/393) (4/4)
Aorta 4 No (1/562) (4/4)
Bone 4 No (1/539)
Brain 4 No (6/562) (4/4)
Brainstem 4 No (4/562) (4/4)
Brown adipose tissue 4 No (4/4)
Cartilage tissue 4 No (1/562) (4/4)
Cerebellum 4 No (4/562) (4/4)
Cerebral cortex 4 No (5/562) (4/4)
Esophagus 4 No (2/393) (3/4)
Eye 4 No (1/562) (4/4)
Gall bladder 4 No (3/4)
Heart 4 No (3/562) (4/4)
Hippocampus 4 No (5/562) (4/4)
Hypothalamus 4 No (4/562) (4/4)
Kidney 4 No (20/562) (4/4)
Large intestine 4 No (12/562)
Liver 4 No
Lower urinary tract 4 No (3/562) (4/4)
Lung 4 No (3/562)
Lymph node 4 No (1/562)
Mammary gland 4 No (1/4)
Olfactory lobe 4 No (4/393) (3/4)
Oral epithelium 4 No
Ovary 4 No (1/562) (2/4)
Oviduct 4 No (2/562) (2/4)
Pancreas 4 No (6/562) (4/4)
Parathyroid gland 4 No (2/540) (3/4)
Peripheral nervous system 4 No (3/562) (4/4)
Peyer's patch 4 No (1/393)
Pituitary gland 4 No (1/562)
Prostate gland 4 No (5/562)
Skeletal muscle 4 No
Skin 4 No (1/562) (4/4)
Small intestine 4 No (11/562)
Spinal cord 4 No (3/562) (4/4)
Spleen 4 No (4/562)
Stomach 4 No (9/562) (4/4)
Striatum 4 No (4/562) (4/4)
Testis 4 No (4/562) (2/4)
Thymus 4 No
Thyroid gland 4 No (16/562)
Trachea 4 No (3/562) (3/4)
Uterus 4 No (2/562) (2/4)
Vascular system 4 No (1/393)
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/440) (4/4)
Ear 2 (1/440) (2/4)
Embryo 2 (1/440) (4/4)
Eye 2 (1/440) (4/4)
Foot 2 (4/4)
Forebrain 2 (1/440) (4/4)
Forelimb 2 (1/440) (4/4)
Hand 2 (4/4)
Head 2 (5/440) (4/4)
Heart 2 (1/440) (2/4)
Hindbrain 2 (5/440) (4/4)
Hindlimb 2 (1/440) (4/4)
Liver 2 (1/440) (2/4)
Lung 2 (1/440) (2/4)
Mandibular process 2 (1/440) (2/4)
Maxillary process 2 (1/440) (2/4)
Midbrain 2 (1/440) (4/4)
Oral cavity 2 (1/440) (2/4)
Skin 2 (1/440) (2/4)
Tail 2 (1/440) (4/4)
Tail somite 2 (1/440) (4/4)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    13 Images
  • X-ray: XRay Images Lateral Orientation
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    5 Images
  • Adult LacZ: LacZ Images Wholemount
    21 Images
  • Echo: M-Mode Images
    40 Images
  • Embryo LacZ: LacZ images wholemount
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Hipk2tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Hipk2tm2b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Hipk2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene