Gene: Ncoa3

Order

Name nuclear receptor coactivator 3

Synonyms
  • bHLHe42
  • TRAM1
  • 2010305B15Rik
  • KAT13B
  • pCIP
  • Src3
  • RAC3
  • AIB1
  • TRAM-1

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:1276535    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Ncoa3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Ncoa3 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Ncoa3tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
abnormal tooth morphology Ncoa3tm1b(EUCOMM)Wtsi HET Male postnatal 2.36E-13
impaired glucose tolerance Ncoa3tm1b(EUCOMM)Wtsi HET Male postnatal 2.39E-9
persistence of hyaloid vascular system Ncoa3tm1b(EUCOMM)Wtsi HET Male postnatal 1.07E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No (2/2)
Bone 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Gall bladder 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No (2/2)
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No
Oral epithelium 2 No (1/2)
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (1/2)
Trachea 2 No
Uterus 2 No
Vascular system 2 No (2/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    sensory organ
    reproductive system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    15 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    15 Images
  • Echo: M-Mode Images
    32 Images
  • X-ray: XRay Images Lateral Orientation
    15 Images
  • Adult LacZ: LacZ Images Wholemount
    10 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    5 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Ncoa3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Ncoa3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Ncoa3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Ncoa3tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette)
Vector
Gene