Gene: Cbx4

Order

Name chromobox 4

Synonyms
  • MPc2
  • PC2

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:1195985    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Cbx4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cbx4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Cbx4tm1.1(KOMP)Vlcg HET embryonic day 15.5 0.0
abnormal embryo size Cbx4tm1.1(KOMP)Vlcg HOM embryonic day 15.5 0.0
preweaning lethality, complete penetrance Cbx4tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
decreased lean body mass Cbx4tm1.1(KOMP)Vlcg HET Male postnatal 5.9E-6
abnormal behavior Cbx4tm1.1(KOMP)Vlcg HET Female Male postnatal 1.76E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (1/2)
Aorta 2 No
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Cartilage tissue 2 No
Cerebellum 2 No
Cerebral cortex 2 No
Esophagus 2 No (7/415)
Eye 2 No
Heart 2 No
Hippocampus 2 No
Hypothalamus 2 No
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No (1/2)
Mammary gland 2 No
Olfactory lobe 2 No (1/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (1/2)
Striatum 2 No
Testis 2 No (2/584) (1/2)
Thymus 2 No (1/2)
Thyroid gland 2 No (15/584) (1/2)
Tongue 1 No (5/127) (1/1)
Trachea 2 No
Uterus 2 No
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    respiratory system
    digestive system
    nervous system
    sensory organ
    reproductive system
    immune system
    exocrine system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 4 (1/51)
Brain 4 (6/485) (4/6)
Central nervous system ganglion 4 (1/51)
Ear 4 (1/485)
Embryo 4 (1/485) (4/6)
Eye 4 (1/485) (4/6)
Foot 4 (1/485)
Forebrain 4 (1/485) (4/6)
Forelimb 4 (1/485) (4/6)
Gut 4 (1/50)
Hand 4 (1/485)
Head 4 (5/485)
Heart 4 (1/485) (4/6)
Hindbrain 4 (6/485) (4/6)
Hindlimb 4 (1/485) (4/6)
Liver 4 (1/485)
Lung 4 (1/485)
Mandibular process 4 (1/485) Image Only
Maxillary process 4 (1/485)
Midbrain 4 (1/485) (4/6)
Nose 4 (1/51) (4/4)
Oral cavity 4 (1/485) (4/6)
Skeleton 4 (1/51)
Skin 4 (1/485)
Spinal cord 4 (1/50) (4/4)
Tail 4 (1/485) (4/6)
Tail somite 4 (1/485) (4/6)
Trachea 4 (1/50)
Urinary system 4 (1/50)


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    28 Images
  • X-ray: XRay Images Dorso Ventral
    14 Images
  • X-ray: XRay Images Hind Leg and Hip
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • Adult LacZ: LacZ Images Section
    28 Images
  • Eye Morphology: Images Slit Lamp
    2 Images
  • Gross Pathology and Tissue Collection
    8 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cbx4tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Cbx4tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Cbx4tm380190(L1L2_Bact_P)
Vector
Gene