Gene: Med1

Order

Name mediator complex subunit 1

Synonyms
  • TRAP 220
  • PBP
  • Pparbp
  • DRIP205
  • CRSP210
  • TRAP220
  • l11Jus15

Status ES CellsMice
tm3b
Mice
tm3a
phenotype data available

Links MGI:1100846    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Med1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Med1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Med1tm3b(EUCOMM)Wtsi HOM Female Male embryonic day 12.5 0.0
abnormal embryo size Med1tm3b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal eye morphology Med1tm3b(EUCOMM)Wtsi HOM Female Male embryonic day 12.5 0.0
abnormal eye morphology Med1tm3b(EUCOMM)Wtsi HET Female postnatal 0.0
abnormal forebrain development Med1tm3b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal heart morphology Med1tm3b(EUCOMM)Wtsi HET Male postnatal 0.0
abnormal neural tube closure Med1tm3b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
abnormal placenta size Med1tm3b(EUCOMM)Wtsi HOM Male embryonic day 12.5 0.0
embryonic growth retardation Med1tm3b(EUCOMM)Wtsi HET Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Med1tm3b(EUCOMM)Wtsi HOM Female Male embryonic day 12.5 0.0
enlarged heart Med1tm3b(EUCOMM)Wtsi HET Male postnatal 0.0
enlarged uterus Med1tm3b(EUCOMM)Wtsi HET Female postnatal 0.0
hydrometra Med1tm3b(EUCOMM)Wtsi HET Female postnatal 0.0
pale yolk sac Med1tm3b(EUCOMM)Wtsi HOM Male embryonic day 12.5 0.0
pallor Med1tm3b(EUCOMM)Wtsi HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Med1tm3b(EUCOMM)Wtsi HOM Female Male n/a 0.0
small superior vagus ganglion Med1tm3b(EUCOMM)Wtsi HET Female postnatal 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415)
Aorta 2 No
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No
Cartilage tissue 2 No
Cecum 2 No (12/383)
Cerebellum 2 No
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127)
Diaphragm 2 No
Duodenum 2 No (2/127)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415)
Eye 2 No
Gall bladder 2 No
Gonadal fat pad 2 No
Harderian gland 2 No
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127)
Jejunum 2 No (6/127)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No
Lower urinary tract 2 No
Lung 2 No
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No
Midbrain 2 No
Olfactory lobe 2 No
Ovary 2 No (1/584)
Oviduct 2 No
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Parotid gland 2 No
Penis 2 No
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584)
Quadriceps 2 No
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No
Small intestine 2 No (9/584)
Spinal cord 2 No
Spleen 2 No (2/584)
Stomach 2 No (12/584)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No
Submandibular gland 2 No (2/132)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127)
Trachea 2 No
Trigeminal V nerve 2 No
Urinary bladder 2 No
Uterus 2 No
Vagina 2 No
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse reproductive system trunk urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    10 Images
  • X-ray: XRay Images Dorso Ventral
    10 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Med1tm3b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue
Med1tm3a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Med1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene