Gene: Aak1

Name AP2 associated kinase 1

Synonyms
  • D6Ertd245e
  • 5530400K14Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:1098687   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Subviable

Phenotype associations for Aak1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Aak1 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased or absent threshold for auditory brainstem response Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 0.0
preweaning lethality, incomplete penetrance Aak1tm1b(EUCOMM)Hmgu HOM Female Male n/a 0.0
short tibia Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 3.21E-16
increased vertical activity Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 2.44E-14
decreased startle reflex Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 5.17E-10
decreased circulating total protein level Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 4.32E-8
abnormal eye anterior chamber depth Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 2.82E-7
abnormal sensory capabilities/reflexes/nociception Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 4.82E-6
decreased circulating serum albumin level Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 6.7E-6
increased mean corpuscular volume Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 2.59E-5
abnormal behavior Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 4.94E-5
decreased circulating cholesterol level Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 6.82E-5
increased circulating alkaline phosphatase level Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 7.1E-5
decreased circulating HDL cholesterol level Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 7.16E-5
abnormal retinal outer nuclear layer morphology Aak1tm1b(EUCOMM)Hmgu HOM Female Male postnatal 9.94E-5

Download data as: TSV XLS



Expression

Expression data not available

Associated Images

Associated Images
  • X-ray: XRay Images Lateral Orientation
    16 Images
  • X-ray: XRay Images Dorso Ventral
    16 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Aak1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Aak1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre)
Vector
Gene