Gene: Erf

Order

Name Ets2 repressor factor

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:109637    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Erf

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Erf data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Erftm1.1(KOMP)Mbp HET Female Male embryonic day 9.5 0.0
abnormal embryo size Erftm1.1(KOMP)Mbp HOM Female embryonic day 9.5 0.0
abnormal heart morphology Erftm1.1(KOMP)Mbp HET Female Male postnatal 0.0
embryonic growth retardation Erftm1.1(KOMP)Mbp HOM Female embryonic day 9.5 0.0
embryonic growth retardation Erftm1.1(KOMP)Mbp HET Female Male embryonic day 9.5 0.0
embryonic lethality prior to organogenesis Erftm1.1(KOMP)Mbp HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Erftm1.1(KOMP)Mbp HOM Female Male embryonic day 12.5 0.0
enlarged heart Erftm1.1(KOMP)Mbp HET Female Male postnatal 0.0
hydrometra Erftm1.1(KOMP)Mbp HET Female postnatal 0.0
preweaning lethality, complete penetrance Erftm1.1(KOMP)Mbp HOM Female Male n/a 0.0
small superior vagus ganglion Erftm1.1(KOMP)Mbp HET Female postnatal 0.0
urinary bladder obstruction Erftm1.1(KOMP)Mbp HET Male postnatal 0.0
abnormal snout morphology Erftm1.1(KOMP)Mbp HET Female Male postnatal 7.47E-16
decreased body length Erftm1.1(KOMP)Mbp HET Female Male postnatal 3.27E-7
decreased circulating triglyceride level Erftm1.1(KOMP)Mbp HET Female Male postnatal 5.77E-7
decreased lean body mass Erftm1.1(KOMP)Mbp HET Female Male postnatal 2.95E-6
decreased blood urea nitrogen level Erftm1.1(KOMP)Mbp HET Female Male postnatal 1.76E-5
decreased grip strength Erftm1.1(KOMP)Mbp HET Female Male postnatal 2.22E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No
Cecum 2 No (12/383) (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (2/2)
Diaphragm 2 No (2/2)
Duodenum 2 No (2/127) (2/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No (2/2)
Gall bladder 2 No
Gonadal fat pad 2 No (1/2)
Harderian gland 2 No (2/2)
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (2/2)
Jejunum 2 No (6/127) (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No (2/2)
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No (1/2)
Mesenteric lymph node 2 No (2/2)
Mesenteric adipose tissue 2 No (2/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (1/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Parathyroid gland 2 No (1/2)
Parotid gland 2 No (2/2)
Penis 2 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584)
Quadriceps 2 No (2/2)
Sciatic nerve 2 No (1/2)
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (2/2)
Stomach 2 No (12/584) (2/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No (2/2)
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (2/2)
Tongue 2 No (5/127) (2/2)
Trachea 2 No (2/2)
Trigeminal V nerve 2 No (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vagina 2 No (1/2)
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system limb digestive system cardiovascular system set of connective tissues reproductive system adipose tissue musculoskeletal system trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    10 Images
  • X-ray: XRay Images Lateral Orientation
    10 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Erftm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Erftm1.1(KOMP)Mbp Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Fixed Tissue