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Gene: Rgs16 MGI:108407

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
regulator of G-protein signaling 16
Synonyms:
Rgsr

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Rgs16 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Rgs16 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Immunodeficiency 24
Decreased circulating IgG level, Recurrent viral infections, Respiratory tract infection, Severe ... OMIM:615897
Monocyte Chemotactic Disorder
Cutaneous anergy, Chronic mucocutaneous candidiasis OMIM:252250
Immunodeficiency 18
Recurrent otitis media, Recurrent respiratory infections, Defective T cell proliferation, Recurre... OMIM:615615
Immunodeficiency, X-Linked, With Deficiency Of 115,000 Dalton Surface Glycoprotein
Recurrent bacterial infections, Abnormality of T cell physiology, Recurrent protozoan infections,... OMIM:308220
Interstitial Lung Disease 2
Alveolar cell carcinoma, Increased circulating antibody level, Pulmonary fibrosis, Elevated bronc... OMIM:178500
Riddle Syndrome
Decreased circulating IgG level, Pulmonary fibrosis OMIM:611943
Immunodeficiency 60 And Autoimmunity
Recurrent sinopulmonary infections, Bronchiectasis, Ulcerative colitis, Decreased circulating tot... OMIM:618394
Candidiasis, Familial, 1
Cutaneous anergy, Chronic mucocutaneous candidiasis, Recurrent viral infections OMIM:114580
Retinal Telangiectasia And Hypogammaglobulinemia
Reduced delayed hypersensitivity, Decreased circulating IgG level OMIM:267900
Immunodeficiency 85 And Autoimmunity
Recurrent respiratory infections, Eczema, Oligoarthritis, Persistent EBV viremia, Decreased circu... OMIM:619510
Immunodeficiency 73B With Defective Neutrophil Chemotaxis And Lymphopenia
Recurrent respiratory infections, Decreased lymphocyte proliferation in response to anti-CD3, Par... OMIM:618986
Idiopathic Pulmonary Fibrosis
Bronchiectasis, Abnormal pulmonary interstitial morphology, Honeycomb lung, Pulmonary fibrosis, R... ORPHA:2032
Immunodeficiency, Ovarian Dysgenesis, And Pulmonary Fibrosis
Decreased circulating total IgM, Decreased circulating IgG level, Pulmonary fibrosis, Decreased c... OMIM:611926
Scedosporiosis
Unusual skin infection, Pericarditis, Sinusitis, Arthralgia/arthritis, Pneumonia, Bronchitis, Ost... ORPHA:449280
Cystic Hamartoma Of Lung And Kidney
Recurrent respiratory infections, Pulmonary fibrosis ORPHA:2111
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 3
Pulmonary fibrosis, Usual interstitial pneumonia OMIM:616373
Immunodeficiency, X-Linked, With Magnesium Defect, Epstein-Barr Virus Infection, And Neoplasia
Recurrent respiratory infections, Persistent CMV viremia, Recurrent viral infections, Severe vari... OMIM:300853
Caspase 8 Deficiency
Recurrent sinopulmonary infections, Complete or near-complete absence of specific antibody respon... OMIM:607271
Hemophagocytic Lymphohistiocytosis, Familial, 5, With Or Without Microvillus Inclusion Disease
Recurrent upper respiratory tract infections, Abnormal pulmonary interstitial morphology, Abnorma... OMIM:613101
Immunodeficiency With Hyper-Igm, Type 2
Recurrent infection of the gastrointestinal tract, Recurrent respiratory infections, Impaired Ig ... OMIM:605258
Felty Syndrome
Episcleritis, Recurrent respiratory infections, Recurrent urinary tract infections, Sinusitis, Pe... ORPHA:47612
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 5
Bone marrow hypocellularity, Pulmonary fibrosis OMIM:618674
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 4
Honeycomb lung, Pulmonary fibrosis OMIM:616371
Immunodeficiency 35
Recurrent respiratory infections, Recurrent viral infections, Recurrent mycobacterial infections,... OMIM:611521
Aspergillosis
Sinusitis, Osteomyelitis, Pneumonia, Keratitis, Hypersensitivity pneumonitis, Increased circulati... ORPHA:1163
Immunodeficiency 11A
Recurrent respiratory infections, Pneumocystis jirovecii pneumonia, Decreased circulating antibod... OMIM:615206
Immunodeficiency, Common Variable, 2
Impaired T cell function, Recurrent pneumonia, Bronchiectasis, Recurrent bacterial infections, Co... OMIM:240500
Hepatic Veno-Occlusive Disease-Immunodeficiency Syndrome
Recurrent respiratory infections, Recurrent enteroviral infections, Recurrent ear infections, Rec... ORPHA:79124
Granulomatous Disease, Chronic, Autosomal Recessive, 5
Acute pancreatitis, Eczema, Perianal abscess, Lymphadenitis, Recurrent pneumonia, Recurrent tonsi... OMIM:618935
Immunodeficiency With Hyper-Igm, Type 5
Impaired Ig class switch recombination, Epididymitis, Increased circulating IgM level, Recurrent ... OMIM:608106
Lung Disease, Immunodeficiency, And Chromosome Breakage Syndrome
Eczema, Increased circulating IgE level, Bronchiolitis obliterans, Increased circulating IgM leve... OMIM:617241
Pulmonary Hemosiderosis
Recurrent intrapulmonary hemorrhage, Pulmonary fibrosis OMIM:178550
Immunodeficiency, Common Variable, 1
Impaired T cell function, Pneumonia, Recurrent pneumonia, Bronchiectasis, Decreased circulating t... OMIM:607594
Sarcoidosis, Susceptibility To, 2
Erythema nodosum, Pneumothorax, Bronchiectasis, Abnormal pulmonary interstitial morphology, Uveit... OMIM:612387
Hypersensitivity Pneumonitis, Familial
Hypersensitivity pneumonitis OMIM:145300
Sting-Associated Vasculopathy, Infantile-Onset
Recurrent respiratory infections, Myositis, Skin rash, Increased circulating IgA level, Pustule, ... OMIM:615934
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 6
Pulmonary fibrosis, Bone marrow hypocellularity, Decreased circulating antibody level OMIM:619767
Bare Lymphocyte Syndrome, Type Ii
Viral hepatitis, Chronic lymphocytic meningitis, Recurrent urinary tract infections, Cholangitis,... OMIM:209920
Acute Lung Injury
Increased circulating interleukin 6 concentration, Acute pancreatitis, Pneumonia, Diffuse alveola... ORPHA:178320
Surfactant Metabolism Dysfunction, Pulmonary, 3
Nonspecific interstitial pneumonia, Crazy paving pattern, Nodular pattern on pulmonary HRCT, Desq... OMIM:610921
Immunodeficiency 66
Recurrent skin infections, Pustule, Sepsis, Defective T cell proliferation, Meningitis OMIM:618847
Chronic Beryllium Disease
Pulmonary fibrosis, Hypersensitivity pneumonitis, Lymphocytic interstitial pneumonia, Reticulonod... ORPHA:133
Agammaglobulinemia, X-Linked
Sepsis, Decreased circulating IgE, Conjunctivitis, Decreased circulating IgG level, Infectious en... OMIM:300755
Surfactant Metabolism Dysfunction, Pulmonary, 2
Nonspecific interstitial pneumonia, Spontaneous pneumothorax, Intralobular septal thickening, Des... OMIM:610913
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 1
Reticular pattern on pulmonary HRCT, Bone marrow hypocellularity, Usual interstitial pneumonia, P... OMIM:614742
Severe Combined Immunodeficiency Due To Adenosine Deaminase Deficiency
Inflammatory abnormality of the skin, Sinusitis, Recurrent opportunistic infections, Recurrent up... ORPHA:277
Riddle Syndrome
Pneumonia, Bronchitis, Recurrent viral infections, Recurrent pneumonia, Abnormal pulmonary inters... ORPHA:420741
Acute Interstitial Pneumonia
Peribronchovascular interstitial thickening, Nodular pattern on pulmonary HRCT, Atelectasis, Bron... ORPHA:79126
Autosomal Recessive Spastic Paraplegia Type 70
Abnormal pulmonary interstitial morphology ORPHA:401835
Bone Marrow Failure Syndrome 5
Pulmonary fibrosis, Decreased circulating antibody level OMIM:618165
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 2
Bone marrow hypocellularity, Pulmonary fibrosis OMIM:614743
Wiskott-Aldrich Syndrome 2
Defective T cell proliferation, Recurrent infections, Eczema, Reduced natural killer cell activity OMIM:614493
Immunodeficiency By Defective Expression Of Mhc Class Ii
Recurrent infection of the gastrointestinal tract, Recurrent respiratory infections, Recurrent he... ORPHA:572
Poikiloderma, Hereditary Fibrosing, With Tendon Contractures, Myopathy, And Pulmonary Fibrosis
Erysipelas, Pulmonary fibrosis OMIM:615704
Plectin-Related Limb-Girdle Muscular Dystrophy R17
Bronchiolitis, Atelectasis, Pulmonary fibrosis ORPHA:254361
Pulmonary Fibrosis-Hepatic Hyperplasia-Bone Marrow Hypoplasia Syndrome
Bone marrow hypocellularity, Abnormal pleura morphology, Pulmonary fibrosis ORPHA:210136
Antisynthetase Syndrome
Recurrent respiratory infections, Myositis, Skin rash, Myocarditis, Abnormal pulmonary interstiti... ORPHA:81
Retinal Dystrophy With Or Without Extraocular Anomalies
Pulmonary fibrosis OMIM:617175
Immunodeficiency 41 With Lymphoproliferation And Autoimmunity
Recurrent respiratory infections, Psoriasiform dermatitis, Decreased lymphocyte proliferation in ... OMIM:606367
Immunodeficiency 96
Eczema, Recurrent infections, Decreased circulating total IgM, Defective T cell proliferation, Re... OMIM:619774
Pulmonary Nodular Lymphoid Hyperplasia
Nodular pattern on pulmonary HRCT ORPHA:60026
Reticular Dysgenesis
Sepsis, Impaired T cell function, Lack of T cell function OMIM:267500
Immunodeficiency With Hyper-Igm, Type 1
Sepsis, Decreased circulating IgE, Decreased circulating IgG level, Meningitis, Impaired memory B... OMIM:308230
Interstitial Lung Disease 1
Nonspecific interstitial pneumonia, Intralobular septal thickening, Elevated bronchoalveolar lava... OMIM:619611
Asbestos Intoxication
Atelectasis, Pleural thickening, Abnormal pulmonary interstitial morphology, Pulmonary fibrosis, ... ORPHA:2302
Immunodeficiency 13
Recurrent shingles, Recurrent upper respiratory tract infections, Bronchiolitis obliterans organi... OMIM:615518
T-Cell Immunodeficiency With Thymic Aplasia
Sinusitis, Sepsis, Recurrent candida infections, Chronic otitis media, Opportunistic infection, M... ORPHA:83471
Autoimmune Interstitial Lung, Joint, And Kidney Disease
Crescentic glomerulonephritis, Abnormal pulmonary interstitial morphology, Arthritis, Hemosiderin... OMIM:616414
Mixed Connective Tissue Disease
Myositis, Pericarditis, Skin rash, Gastritis, Myocarditis, Abnormal pulmonary interstitial morpho... ORPHA:809
Lymphoid Interstitial Pneumonia
Multiple pulmonary cysts, Skin rash, Eczema, Respiratory tract infection, Severe viral infection,... ORPHA:79128
Idiopathic Pulmonary Hemosiderosis
Glomerulonephritis, Nodular pattern on pulmonary HRCT, Diffuse alveolar hemorrhage, Pulmonary fib... ORPHA:99931
Autoimmune Disease, Multisystem, Infantile-Onset, 1
Eczema, Desquamative interstitial pneumonitis, Recurrent upper respiratory tract infections, Decr... OMIM:615952
Hermansky-Pudlak Syndrome 2
Reduced natural killer cell activity, Impaired ADP-induced platelet aggregation, Recurrent pneumo... OMIM:608233
Hereditary Mucoepithelial Dysplasia
Recurrent respiratory infections, Pulmonary fibrosis ORPHA:1839
Limited Cutaneous Systemic Sclerosis
Pulmonary fibrosis ORPHA:220402
Choreoathetosis And Congenital Hypothyroidism With Or Without Pulmonary Dysfunction
Recurrent respiratory infections, Atelectasis, Elevated bronchoalveolar lavage fluid neutrophil p... OMIM:610978
Niemann-Pick Disease, Type B
Recurrent respiratory infections, Abnormal pulmonary interstitial morphology OMIM:607616
Autoimmune Lymphoproliferative Syndrome
Gastritis, Glomerulonephritis, Increased circulating IgA level, Increased circulating IgE level, ... ORPHA:3261
Immunodeficiency 91 And Hyperinflammation
Membranoproliferative glomerulonephritis, Maculopapular exanthema, BCGosis, Recurrent pneumonia, ... OMIM:619644
Immunodeficiency 97 With Autoinflammation
Recurrent sinopulmonary infections, Recurrent urinary tract infections, Recurrent skin infections... OMIM:619802
Immunodeficiency 58
Colitis, Chronic otitis media, Recurrent cutaneous abscess formation, Bronchiectasis, Decreased c... OMIM:618131
Fanconi Renotubular Syndrome 5
Emphysema, Pulmonary fibrosis, Lung adenocarcinoma OMIM:618913
T-B+ Severe Combined Immunodeficiency Due To Jak3 Deficiency
Recurrent respiratory infections, Skin rash, Partial IgA deficiency, Recurrent viral infections, ... ORPHA:35078
Sarcoidosis, Susceptibility To, 1
Abnormality of T cell physiology, Iridocyclitis, Bronchiectasis, Abnormal pulmonary interstitial ... OMIM:181000
Reactive Arthritis
Recurrent urinary tract infections, Pericarditis, Osteomyelitis, Abnormal pleura morphology, Pust... ORPHA:29207
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, Nk Cell-Negative
Pneumonia, Decreased lymphocyte proliferation in response to anti-CD3, Meningitis, Recurrent uppe... OMIM:600802
X-Linked Intellectual Disability-Short Stature-Overweight Syndrome
Pulmonary fibrosis ORPHA:457240
Braddock Syndrome
Pulmonary fibrosis ORPHA:52047
Polymyositis
Arthritis, Pericarditis, Abnormal pulmonary interstitial morphology, Pulmonary fibrosis ORPHA:732
T-Cell Immunodeficiency With Thymic Aplasia
Recurrent viral infections, Recurrent bronchopulmonary infections, Recurrent pneumonia, Bronchiec... OMIM:242700
Chronic Recurrent Multifocal Osteomyelitis 2, With Periostitis And Pustulosis
Osteomyelitis, Skin rash, Pustule, Pulmonary fibrosis, Stomatitis OMIM:612852
Idiopathic Chronic Eosinophilic Pneumonia
Atelectasis, Hypersensitivity pneumonitis, Increased circulating IgE level, Atopic dermatitis, Pl... ORPHA:2902
Diffuse Alveolar Hemorrhage
Irregular septal thickening on pulmonary HRCT, Pulmonary fibrosis ORPHA:90060
Fibrosis, Neurodegeneration, And Cerebral Angiomatosis
Recurrent respiratory infections, Atelectasis, Recurrent infections, Pulmonary fibrosis, Decrease... OMIM:618278
Q Fever
Pericarditis, Osteomyelitis, Maculopapular exanthema, Pneumonia, Unusual infection, Myocarditis, ... ORPHA:781
Severe Combined Immunodeficiency Due To Complete Rag1/2 Deficiency
Skin rash, Recurrent viral infections, Lymphadenitis, Decreased circulating antibody level, Decre... ORPHA:331206
Purine Nucleoside Phosphorylase Deficiency
Recurrent urinary tract infections, Sinusitis, Pneumonia, Impaired T cell function, Recurrent vir... OMIM:613179
Interstitial Pneumonitis, Desquamative, Familial
Desquamative interstitial pneumonitis, Recurrent upper respiratory tract infections, Type II pneu... OMIM:263000
Respiratory Bronchiolitis-Interstitial Lung Disease Syndrome
Respiratory tract infection, Hypersensitivity pneumonitis, Bronchiectasis, Honeycomb lung, Chroni... ORPHA:79127
Granulomatosis With Polyangiitis
Recurrent respiratory infections, Pericarditis, Recurrent intrapulmonary hemorrhage, Sinusitis, S... ORPHA:900
Hermansky-Pudlak Syndrome 4
Pulmonary fibrosis OMIM:614073
Typhoid
Skin rash, Infectious encephalitis, Abnormal pulmonary interstitial morphology ORPHA:99745
46,Xx Gonadal Dysgenesis
Pulmonary fibrosis ORPHA:243
Fusariosis
Brain abscess, Fasciitis, Lung abscess, Sinusitis, Pneumonia, Myositis, Maculopapular exanthema, ... ORPHA:228119
Diffuse Cutaneous Systemic Sclerosis
Arthritis, Pulmonary fibrosis ORPHA:220393
Brain-Lung-Thyroid Syndrome
Recurrent respiratory infections, Recurrent pneumonia, Pulmonary fibrosis, Abnormal pulmonary int... ORPHA:209905
Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 7
Emphysema, Pulmonary fibrosis OMIM:620365
Dyskeratosis Congenita, Autosomal Recessive 1
Bone marrow hypocellularity, Pulmonary fibrosis OMIM:224230
Hermansky-Pudlak Syndrome 1
Inflammation of the large intestine, Colitis, Pulmonary fibrosis OMIM:203300
Systemic Sclerosis
Pericarditis, Osteomyelitis, Recurrent skin infections, Glomerulonephritis, Myocarditis, Abnormal... ORPHA:90291
Primary Ciliary Dyskinesia
Recurrent sinopulmonary infections, Peribronchovascular interstitial thickening, Pulmonary situs ... ORPHA:244
Chitayat Syndrome
Recurrent respiratory infections, Abnormal pulmonary interstitial morphology OMIM:617180
Dyskeratosis Congenita, Autosomal Dominant 2
Bone marrow hypocellularity, Pulmonary fibrosis OMIM:613989
Autoimmune Polyendocrinopathy Type 4
Atrophic gastritis, Iridocyclitis, Abnormal pulmonary interstitial morphology, Chronic mucocutane... ORPHA:227990
Dyskeratosis Congenita, Autosomal Dominant 1
Interstitial pneumonitis, Bone marrow hypocellularity, Pulmonary fibrosis OMIM:127550
Dyskeratosis Congenita, Autosomal Dominant 3
Bone marrow hypocellularity, Pulmonary fibrosis OMIM:613990
Bronchiolitis Obliterans With Obstructive Pulmonary Disease
Respiratory tract infection, Bronchiolitis obliterans, Bronchiectasis, Pneumonia ORPHA:1303
Autoimmune Polyendocrinopathy Type 3
Atrophic gastritis, Iridocyclitis, Abnormal pulmonary interstitial morphology, Chronic mucocutane... ORPHA:227982
Erdheim-Chester Disease
Osteomyelitis, Skin rash, Abnormal pulmonary interstitial morphology, Pulmonary fibrosis, Pleural... ORPHA:35687
Immune-Mediated Necrotizing Myopathy
Myocarditis, Myositis, Skin rash, Abnormal pulmonary interstitial morphology ORPHA:206569
Pulmonary Alveolar Microlithiasis
Bronchitis, Respiratory tract infection, Pleural thickening, Pneumothorax, Bronchiectasis, Subple... ORPHA:60025
Neonatal Acute Respiratory Distress Due To Sp-B Deficiency
Intraalveolar phospholipid accumulation, Interstitial pneumonitis, Abnormal pulmonary interstitia... ORPHA:217563
Juvenile Dermatomyositis
Myositis, Pericarditis, Skin rash, Arthritis, Pulmonary fibrosis ORPHA:93672
Car T Cell Therapy-Associated Cytokine Release Syndrome
Increased inflammatory response, Increased circulating interleukin 6 concentration, Skin rash, In... ORPHA:542323
Gaucher Disease
Osteomyelitis, Osteoarthritis, Abnormal pulmonary interstitial morphology, Hepatitis, Increased c... ORPHA:355
Primary Sjögren Syndrome
Myositis, Chronic active hepatitis, Parotitis, Lymphocytic interstitial pneumonia, Bronchitis, Gl... ORPHA:289390
Gaucher Disease Type 1
Osteoarthritis, Increased circulating antibody level, Abnormal pulmonary interstitial morphology ORPHA:77259
Interstitial Lung And Liver Disease
Intraalveolar phospholipid accumulation, Abnormal pulmonary interstitial morphology, Pulmonary fi... OMIM:615486
Cerebroretinal Microangiopathy With Calcifications And Cysts 1
Bone marrow hypocellularity, Pulmonary fibrosis OMIM:612199
Idiopathic Hypereosinophilic Syndrome
Inflammatory abnormality of the skin, Cholangitis, Eczema, Chronic hepatitis, Arthritis, Colitis,... ORPHA:3260
Dermatomyositis
Recurrent respiratory infections, Pericarditis, Myocarditis, Abnormal pulmonary interstitial morp... ORPHA:221
Inflammatory Bowel Disease, Immunodeficiency, And Encephalopathy
Recurrent respiratory infections, Candida esophagitis, Eosinophilic infiltration of the esophagus... OMIM:618213
Rajab Interstitial Lung Disease With Brain Calcifications 2
Abnormal pulmonary interstitial morphology OMIM:619013
Brucellosis
Bronchitis, Knee osteoarthritis, Increased circulating IgG level, Infectious encephalitis, Epidid... ORPHA:1304
Respiratory Infections, Recurrent, And Failure To Thrive With Or Without Diarrhea
Atelectasis, Abnormal pulmonary interstitial morphology, Bronchiectasis, Recurrent otitis media, ... OMIM:620233
Niemann-Pick Disease, Type C2
Pulmonary fibrosis OMIM:607625
Overlap Myositis
Arthritis, Severe infection, Abnormal pulmonary interstitial morphology, Rheumatoid arthritis ORPHA:206572
Al Amyloidosis
Increased circulating antibody level, Abnormal pulmonary interstitial morphology, Pulmonary inter... ORPHA:85443
Wild Type Attr Amyloidosis
Pleural effusion, Abnormal pulmonary interstitial morphology, Pulmonary edema ORPHA:330001
Wiskott-Aldrich Syndrome
Recurrent herpes, Eczema, Reduced natural killer cell activity, Increased circulating IgA level, ... OMIM:301000
Gaucher Disease Type 3
Recurrent respiratory infections, Increased circulating antibody level, Abnormal pulmonary inters... ORPHA:77261
Sarcoidosis
Maculopapular exanthema, Abnormal pleura morphology, Erythema nodosum, Abnormal lung morphology, ... ORPHA:797
Congenital Myopathy 21 With Early Respiratory Failure
Lipoid pneumonia OMIM:620326
Hermansky-Pudlak Syndrome
Pulmonary fibrosis ORPHA:79430
Kawasaki Disease
Pericarditis, Skin rash, Recurrent pharyngitis, Myocarditis, Abnormal pulmonary interstitial morp... ORPHA:2331
Surfactant Metabolism Dysfunction, Pulmonary, 1
Desquamative interstitial pneumonitis, Intraalveolar phospholipid accumulation, Absent bronchoalv... OMIM:265120
Hermansky-Pudlak Syndrome 10
Recurrent respiratory infections, Abnormal pulmonary interstitial morphology OMIM:617050
Congenital Disorder Of Glycosylation, Type Iil
Inflammation of the large intestine, Decreased specific anti-polysaccharide antibody level, Impai... OMIM:614576
Dyskeratosis Congenita, X-Linked
Conjunctivitis, Bone marrow hypocellularity, Blepharitis, Pulmonary fibrosis OMIM:305000
Gaucher Disease-Ophthalmoplegia-Cardiovascular Calcification Syndrome
Abnormal pulmonary interstitial morphology, Pulmonary fibrosis, Bacterial endocarditis ORPHA:2072
Bronchial Neuroendocrine Tumor
Abnormal pulmonary interstitial morphology, Pneumonia ORPHA:97287
Gaucher Disease, Type I
Abnormal pulmonary interstitial morphology OMIM:230800
Hereditary Orotic Aciduria
Recurrent respiratory infections, Impaired T cell function ORPHA:30
Primary Fanconi Renotubular Syndrome
Pulmonary fibrosis ORPHA:3337
Hereditary Pulmonary Alveolar Proteinosis
Acute infectious pneumonia, Crazy paving pattern ORPHA:264675
Aregenerative Anemia
Abnormality of interleukin secretion, Bone marrow hypocellularity ORPHA:101096
Kikuchi-Fujimoto Disease
Skin rash, Pustule, Myocarditis, Abnormal pulmonary interstitial morphology, Pleural effusion, Ma... ORPHA:50918
Knobloch Syndrome 2
Recurrent respiratory infections, Abnormal pulmonary interstitial morphology OMIM:618458
Acrodermatitis Enteropathica, Zinc-Deficiency Type
Impaired T cell function, Recurrent candida infections OMIM:201100
Velocardiofacial Syndrome
Pulmonary artery atresia, Recurrent infections, Impaired T cell function, Unilateral primary pulm... OMIM:192430
Rajab Interstitial Lung Disease With Brain Calcifications 1
Recurrent urinary tract infections, Emphysema, Abnormal pulmonary interstitial morphology OMIM:613658
Cryptococcosis
Osteomyelitis, Pneumonia, Nodular pattern on pulmonary HRCT, Prostatitis, Peritonitis, Sepsis, Pl... ORPHA:1546
Chronic Graft Versus Host Disease
Fasciitis, Urinary bladder inflammation, Pneumothorax, Bronchiectasis, Recurrent infections, Bron... ORPHA:99921
Progeroid Short Stature With Pigmented Nevi
Allergic rhinitis, Allergic conjunctivitis, Impaired T cell function, Recurrent viral infections OMIM:176690
Orotic Aciduria
Impaired T cell function OMIM:258900
Epidermolysis Bullosa, Junctional 7, With Interstitial Lung Disease And Nephrotic Syndrome
Recurrent respiratory infections, Abnormal pulmonary interstitial morphology OMIM:614748
Autoimmune Pulmonary Alveolar Proteinosis
Crazy paving pattern, Intraalveolar phospholipid accumulation ORPHA:747
Hypoparathyroidism-Sensorineural Deafness-Renal Disease Syndrome
Abnormality of T cell physiology, Psoriasiform dermatitis ORPHA:2237
Chronic Visceral Acid Sphingomyelinase Deficiency
Abnormal pulmonary interstitial morphology ORPHA:77293
Ehlers-Danlos Syndrome, Vascular Type
Pulmonary bulla, Recurrent intrapulmonary hemorrhage, Spontaneous pneumothorax, Repeated pneumoth... OMIM:130050
Goodpasture Syndrome
Glomerulonephritis, Nodular pattern on pulmonary HRCT, Hemosiderin-laden macrophages in bronchoal... OMIM:233450

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Rgs16

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Rgs16.

No publications found that use IMPC mice or data for Rgs16.

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MGI Allele Allele Type Produced
Rgs16tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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