Gene: Myd88

Order

Name myeloid differentiation primary response gene 88

Status ES CellsMice
tm1a
phenotype data available

Links MGI:108005    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Myd88

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Myd88 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
increased body weight Myd88tm1a(EUCOMM)Wtsi HOM Female Male postnatal 3.98E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No
Aorta 2 No (1/562)
Blood vessel 2 No
Bone 2 No (1/539)
Brain 2 No (6/562) (1/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562)
Cerebral cortex 2 No (5/562)
Eye 2 No (1/562)
Gall bladder 2 No
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Esophagus 2 No
Olfactory lobe 2 No
Ovary 2 No (1/562)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Parathyroid gland 2 No (2/540)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle tissue 2 No
Skin 2 No (1/562) (1/2)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Testis 2 No (4/562) (1/2)
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Uterus 2 No (2/562)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse nervous system reproductive system integumental system trunk
No expression image was found for this adult tab
No expression data was found for this embryo tab


Secondary lacZ Expression Data
postnatal mouse (7)
  • Myd88tm1a(EUCOMM)Wtsi
    ovary, uterus, HET, Female, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    skin, tail, HET, Male, WTSI

show all 7 images

trunk (4)
  • Myd88tm1a(EUCOMM)Wtsi
    ovary, uterus, HET, Female, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI
integumental system (2)
  • Myd88tm1a(EUCOMM)Wtsi
    skin, tail, HET, Male, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    pinna, skin, HET, Male, WTSI
reproductive system (2)
  • Myd88tm1a(EUCOMM)Wtsi
    ovary, uterus, HET, Female, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    testis, HET, Male, WTSI
digestive system (1)
  • Myd88tm1a(EUCOMM)Wtsi
    small intestine, HET, Female, WTSI
nervous system (1)
  • Myd88tm1a(EUCOMM)Wtsi
    brain, HET, Female, WTSI
sensory organ (1)
  • Myd88tm1a(EUCOMM)Wtsi
    pinna, skin, HET, Male, WTSI
urinary system (1)
  • Myd88tm1a(EUCOMM)Wtsi
    kidney, HET, Female, WTSI

Associated Images

Legacy Phenotype Associated Images
Xray (68)
  • Myd88tm1a(EUCOMM)Wtsi
    body, HOM, Male, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    head, HOM, Male, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    body, HOM, Male, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    body, HOM, Male, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    head, HOM, Male, WTSI

show all 68 images

Eye Morphology (2)
  • Myd88tm1a(EUCOMM)Wtsi
    eye, abnormal retinal pigmentation, HOM, Male, WTSI
  • Myd88tm1a(EUCOMM)Wtsi
    eye, eyelids fail to open, HOM, Female, WTSI
Skin Histopathology (1)
  • Myd88tm1a(EUCOMM)Wtsi
    back skin, HOM, Female, WTSI

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Myd88tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Myd88tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Myd88tm1(NCOM)Cmhd Reporter-tagged deletion allele (with selection cassette)
Vector
Gene