Gene: Rock1

Order

Name Rho-associated coiled-coil containing protein kinase 1

Synonyms
  • 1110055K06Rik
  • Rock-I

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:107927    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Subviable

Phenotype associations for Rock1

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Rock1 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
edema Rock1tm1b(NCOM)Mfgc HOM Female Male embryonic day 15.5 0.0
edema Rock1tm1b(NCOM)Mfgc HET Female Male embryonic day 15.5 0.0
preweaning lethality, incomplete penetrance Rock1tm1b(NCOM)Mfgc HOM Female Male n/a 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
No expression data was found for this adult tab
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51)
Brain 5 (6/485) (2/8)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 5 (1/485) (2/8)
Embryo 5 (1/485) (2/8)
Eye 5 (1/485) (2/8)
Foot 5 (1/485)
Forebrain 5 (1/485) (2/8)
Forelimb 5 (1/485) (2/8)
Gut 2 (1/50) (2/2)
Hand 5 (1/485)
Head 5 (5/485)
Heart 5 (1/485) (2/8)
Hindbrain 5 (6/485) (2/8)
Hindlimb 5 (1/485) (2/8)
Liver 5 (1/485) (2/8)
Lung 5 (1/485)
Mandibular process 5 (1/485)
Maxillary process 5 (1/485)
Midbrain 5 (1/485) (2/8)
Nose 2 (1/51)
Oral cavity 5 (1/485) (2/8)
2 (7/25) (2/2)
Skeleton 2 (1/51) (2/2)
Skin 5 (1/485)
Spinal cord 2 (1/50) (2/2)
Tail 5 (1/485)
Tail somite 5 (1/485) (2/8)
Trachea 2 (1/50)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    11 Images
  • Eye Morphology: Images Ophthalmoscopy
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    11 Images
  • X-ray: XRay Images Lateral Orientation
    11 Images
  • X-ray: XRay Images Skull Lateral Orientation
    11 Images
  • Gross Pathology and Tissue Collection
    10 Images
  • Gross Morphology Embryo E14.5-E15.5
    4 Images
  • Histopathology
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Rock1tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Rock1tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre)
Vector
Gene