Gene: Plcb4

Order

Name phospholipase C, beta 4

Synonyms
  • A930039J07Rik
  • C230058B11Rik

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:107464    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Viable

Phenotype associations for Plcb4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Plcb4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal gallbladder morphology Plcb4tm1b(EUCOMM)Wtsi HOM Female postnatal 0.0
enlarged gallbladder Plcb4tm1b(EUCOMM)Wtsi HOM Female postnatal 0.0
hydrometra Plcb4tm1b(EUCOMM)Wtsi HOM Female postnatal 0.0
small superior vagus ganglion Plcb4tm1b(EUCOMM)Wtsi HOM Female postnatal 0.0
decreased total body fat amount Plcb4tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.6E-16
increased bone mineral content Plcb4tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.56E-13
increased lean body mass Plcb4tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.82E-13
decreased lean body mass Plcb4tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.16E-12
decreased body length Plcb4tm1b(EUCOMM)Wtsi HOM Female Male postnatal 5.24E-10
increased grip strength Plcb4tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.65E-9
abnormal gait Plcb4tm1b(EUCOMM)Wtsi HOM Female Male postnatal 3.95E-9
hypoactivity Plcb4tm1b(EUCOMM)Wtsi HOM Female Male postnatal 1.21E-8
increased or absent threshold for auditory brainstem response Plcb4tm1b(EUCOMM)Wtsi HOM Female Male postnatal 2.9E-6
abnormal locomotor behavior Plcb4tm1b(EUCOMM)Wtsi HOM Male postnatal 9.73E-6

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (2/2)
Aorta 2 No (2/2)
Blood 2 No
Bone marrow 2 No
Brain 2 No
Brainstem 2 No
Brown adipose tissue 2 No (1/2)
Cartilage tissue 2 No
Cecum 2 No (12/383) (1/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No
Chest bone 2 No
Colon 2 No (12/127) (2/2)
Diaphragm 2 No (1/2)
Duodenum 2 No (2/127) (1/2)
Epididymis 2 No (18/134) (1/2)
Esophagus 2 No (7/415) (1/2)
Eye 2 No (2/2)
Gall bladder 2 No
Gonadal fat pad 2 No (1/2)
Harderian gland 2 No (2/2)
Heart 2 No
Hindlimb 2 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 2 No (14/127) (2/2)
Jejunum 2 No (6/127) (1/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584)
Liver 2 No (1/2)
Lower urinary tract 2 No
Lung 2 No (1/2)
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 2 No
Mesenteric adipose tissue 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584)
Parathyroid gland 2 No
Parotid gland 2 No (2/2)
Penis 2 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No (2/2)
Prostate gland 2 No (12/584) (1/2)
Quadriceps 2 No (2/2)
Sciatic nerve 2 No
Skeletal muscle 2 No
Skin 2 No (2/2)
Small intestine 2 No (9/584)
Spinal cord 2 No (1/2)
Spleen 2 No (2/584)
Stomach 2 No (12/584) (2/2)
Stomach pyloric region 2 No
Striatum 2 No
Sublingual gland 2 No (2/2)
Submandibular gland 2 No (2/132) (2/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No (1/2)
Thyroid gland 2 No (15/584)
Tongue 2 No (5/127) (2/2)
Trachea 2 No (2/2)
Trigeminal V nerve 2 No
Urinary bladder 2 No (2/2)
Uterus 2 No (1/2)
Vagina 2 No (1/2)
Vas deferens 2 No (15/388) (1/2)
Vascular system 2 No
Vesicular gland 2 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system respiratory system digestive system cardiovascular system set of connective tissues reproductive system musculoskeletal system adipose tissue trunk postnatal mouse nervous system sensory organ immune system exocrine system integumental system urinary system
No expression image was found for this adult tab
No expression data was found for this embryo tab


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    6 Images
  • X-ray: XRay Images Lateral Orientation
    14 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Plcb4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Plcb4tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue
Plcb4tm39490(L1L2_gt0)
Vector
Gene