Gene: Efna4

Name ephrin A4

Synonyms
  • LERK-4
  • EFL-4
  • Epl4

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:106643   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Subviable

Phenotype associations for Efna4

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Efna4 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
preweaning lethality, incomplete penetrance Efna4tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
impaired pupillary reflex Efna4tm1.1(KOMP)Vlcg HOM Male postnatal 1.15E-9
abnormal cornea morphology Efna4tm1.1(KOMP)Vlcg HOM Female postnatal 1.76E-5
abnormal sleep behavior Efna4tm1.1(KOMP)Vlcg HOM Female postnatal 8.5E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/354)
Aorta 2 No (2/530)
Brain 2 No (8/530)
Brainstem 2 No (5/530)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/530)
Cerebellum 2 No (6/530)
Cerebral cortex 2 No (6/530)
Epididymis 2 No (1/103)
Esophagus 2 No (1/354)
Eye 2 No (1/530)
Heart 2 No (4/530)
Hippocampus 2 No (7/530)
Hypothalamus 2 No (5/529)
Kidney 2 No (13/530) (2/2)
Large intestine 2 No (7/530)
Liver 2 No
Lower urinary tract 2 No (3/530)
Lung 2 No (4/530)
Lymph node 2 No (2/530)
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No (3/354)
Ovary 2 No (1/530) (1/2)
Oviduct 2 No (1/530) (1/2)
Pancreas 2 No (2/530)
Peripheral nervous system 2 No (4/530)
Peyer's patch 2 No (1/354)
Pituitary gland 2 No (2/530)
Prostate gland 2 No (3/530)
Skeletal muscle 2 No
Skin 2 No (2/530) (2/2)
Small intestine 2 No (5/530)
Spinal cord 2 No (5/530)
Spleen 2 No (3/530)
Stomach 2 No (5/530)
Striatum 2 No (6/530)
Submandibular gland 2 No (1/2)
Testis 2 No (7/530) (1/2)
Thalamus 2 No
Thymus 2 No (1/530) (2/2)
Thyroid gland 2 No (11/530)
Trachea 2 No (5/530)
Urinary bladder 2 No
Uterus 2 No (1/530) (1/2)
Vascular system 2 No (1/354)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    respiratory system
    digestive system
    reproductive system
    immune system
    exocrine system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (5/413)
Dorsal root ganglion 2 No Data
Ear 2
Embryo 2
Eye 2
Foot 2
Forebrain 2
Forelimb 2
Fronto-nasal process 2
Hand 2
Head 2 (4/413)
Heart 2
Hindbrain 2 (5/413)
Hindlimb 2
Liver 2
Lung 2
Mandibular process 2
Maxillary process 2
Midbrain 2
Nose 2 No Data
Oral cavity 2
Skin 2
Spinal cord 2 No Data
Tail 2
Tail somite 2


Associated Images

Associated Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse
Efna4tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Efna4tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Efna4tm214483(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene