Gene: Vps25

Order

Name vacuolar protein sorting 25

Synonyms
  • 1110020N13Rik
  • D11Wsu68e

Status ES CellsMice
tm1
Mice
tm1.1
phenotype data available

Links MGI:106354    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Vps25

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Vps25 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Vps25tm1.1(KOMP)Vlcg HET embryonic day 9.5 0.0
embryonic lethality prior to organogenesis Vps25tm1.1(KOMP)Vlcg HOM Female Male embryonic day 9.5 0.0
embryonic lethality prior to tooth bud stage Vps25tm1.1(KOMP)Vlcg HOM Female Male embryonic day 12.5 0.0
preweaning lethality, complete penetrance Vps25tm1.1(KOMP)Vlcg HOM Female Male n/a 0.0
decreased lean body mass Vps25tm1.1(KOMP)Vlcg HET Male postnatal 2.43E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (1/2)
Aorta 2 No (1/2)
Brain 2 No (2/2)
Brainstem 2 No (2/2)
Brown adipose tissue 1 No (1/1)
Cartilage tissue 2 No (2/2)
Cerebellum 2 No (2/2)
Cerebral cortex 2 No (2/2)
Esophagus 2 No (7/415) (2/2)
Eye 2 No
Heart 2 No (2/2)
Hippocampus 2 No (2/2)
Hypothalamus 2 No (2/2)
Kidney 2 No (18/584) (2/2)
Large intestine 2 No (10/584) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No
Lung 2 No (2/2)
Lymph node 2 No
Mammary gland 2 No
Olfactory lobe 2 No (2/2)
Ovary 2 No (1/584) (1/2)
Oviduct 2 No (1/2)
Pancreas 2 No (5/584) (2/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (1/2)
Skeletal muscle 2 No
Skin 2 No (1/2)
Small intestine 2 No (9/584) (2/2)
Spinal cord 2 No (2/2)
Spleen 2 No (2/584) (1/2)
Stomach 2 No (12/584) (1/2)
Striatum 2 No (1/2)
Testis 2 No (2/584) (1/2)
Thymus 2 No
Thyroid gland 2 No (15/584) (1/2)
Trachea 2 No (1/2)
Uterus 2 No (1/2)
Vascular system 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    respiratory system
    endocrine system digestive system cardiovascular system set of connective tissues reproductive system adipose tissue
    trunk
    postnatal mouse
    nervous system
    immune system exocrine system integumental system urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51) (2/2)
Brain 6 (6/485) (2/6)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 6 (1/485) (2/6)
Embryo 6 (1/485) (2/6)
Eye 6 (1/485) (2/6)
Foot 6 (1/485) (2/6)
Forebrain 6 (1/485) (2/6)
Forelimb 6 (1/485) (2/6)
Gut 2 (1/50) (2/2)
Hand 6 (1/485) (2/6)
Head 6 (5/485) (2/6)
Heart 6 (1/485) (2/6)
Hindbrain 6 (6/485) (2/6)
Hindlimb 6 (1/485) (2/6)
Liver 6 (1/485) (2/6)
Lung 6 (1/485) (2/6)
Mandibular process 6 (1/485) (2/6)
Maxillary process 6 (1/485) (2/6)
Midbrain 6 (1/485) (2/6)
Nose 2 (1/51) (2/2)
Oral cavity 6 (1/485) (2/6)
Skeleton 2 (1/51) (2/2)
Skin 6 (1/485) (2/6)
Spinal cord 2 (1/50) (2/2)
Tail 6 (1/485) (2/6)
Tail somite 6 (1/485) Image Only
Trachea 2 (1/50)
Urinary system 2 (1/50)


Associated Images

Associated Images
  • X-ray: XRay Images Dorso Ventral
    14 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    14 Images
  • Adult LacZ: LacZ Images Section
    8 Images
  • Gross Pathology and Tissue Collection
    10 Images
  • X-ray: XRay Images Lateral Orientation
    14 Images
  • Combined SHIRPA and Dysmorphology
    2 Images
  • X-ray: XRay Images Skull Lateral Orientation
    14 Images
  • Eye Morphology: Images Slit Lamp
    3 Images
  • Eye Morphology: Images Ophthalmoscopy
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Vps25tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene
Vps25tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette)
Vector
Gene
Vps25tm290428(L1L2_Bact_P)
Vector
Gene
Vps25tm47348(L1L2_Bact_P)
Vector
Gene