Lepr | leptin receptor
Physiological systems
17 / 24 physiological systems tested
11 Significantly impacted by the knock-out
Liver/biliary system Behavior/neurological Reproductive system Immune system Homeostasis/metabolism Adipose tissue Skeleton Hematopoietic system Endocrine/exocrine gland Cardiovascular system Growth/size/body region
6 No significant impact
7 Not tested
Data collections
Gene metrics:49Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
Human diseases caused by Lepr mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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