Gene: Fgf9

Order

Name fibroblast growth factor 9

Synonyms
  • Eks
  • glia activating factor

Status ES CellsMice
tm1a
Mice
tm1b
phenotype data available

Links MGI:104723    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Fgf9

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Fgf9 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal body wall morphology Fgf9tm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
abnormal embryo size Fgf9tm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
cleft palate Fgf9tm1b(KOMP)Wtsi HOM Female embryonic day 18.5 0.0
embryonic lethality prior to tooth bud stage Fgf9tm1b(KOMP)Wtsi HOM Female Male embryonic day 12.5 0.0
enlarged heart Fgf9tm1b(KOMP)Wtsi HET Male postnatal 0.0
preweaning lethality, complete penetrance Fgf9tm1b(KOMP)Wtsi HOM Female Male n/a 0.0
abnormal retinal vasculature morphology Fgf9tm1b(KOMP)Wtsi HET Female Male postnatal 1.75E-19
cataract Fgf9tm1b(KOMP)Wtsi HET Female Male postnatal 3.59E-16
increased startle reflex Fgf9tm1b(KOMP)Wtsi HET Female Male postnatal 1.08E-10
increased grip strength Fgf9tm1b(KOMP)Wtsi HET Female Male postnatal 2.43E-5
increased mean corpuscular hemoglobin concentration Fgf9tm1b(KOMP)Wtsi HET Male postnatal 9.67E-5
decreased hematocrit Fgf9tm1b(KOMP)Wtsi HET Male postnatal 9.75E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No (2/415) (2/4)
Aorta 4 No
Bone 2 No (2/2)
Brain 4 No (4/4)
Brainstem 4 No (4/4)
Brown adipose tissue 4 No
Cartilage tissue 4 No (2/4)
Cerebellum 4 No (4/4)
Cerebral cortex 4 No (2/4)
Epididymis 2 No (18/134)
Esophagus 4 No (7/415)
Eye 4 No (2/4)
Gall bladder 2 No
Heart 4 No
Hippocampus 4 No (4/4)
Hypothalamus 4 No (2/4)
Kidney 4 No (18/584) (4/4)
Large intestine 4 No (10/584)
Liver 4 No
Lower urinary tract 4 No (2/4)
Lung 4 No
Lymph node 4 No
Mammary gland 4 No
Midbrain 2 No
Olfactory lobe 4 No (2/4)
Oral epithelium 2 No
Ovary 4 No (1/584) (1/4)
Oviduct 4 No (1/4)
Pancreas 4 No (5/584)
Parathyroid gland 2 No (1/2)
Peripheral nervous system 4 No (2/4)
Peyer's patch 4 No
Pituitary gland 4 No (1/4)
Prostate gland 4 No (12/584)
Skeletal muscle 4 No
Skin 4 No (2/4)
Small intestine 4 No (9/584)
Spinal cord 4 No (4/4)
Spleen 4 No (2/584)
Stomach 4 No (12/584)
Striatum 4 No (2/4)
Submandibular gland 2 No (2/132)
Testis 4 No (2/584) (1/4)
Thalamus 2 No
Thymus 4 No
Thyroid gland 4 No (15/584)
Trachea 4 No (2/4)
Urinary bladder 2 No
Uterus 4 No
Vascular system 4 No
Vesicular gland 2 No
White adipose tissue 4 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    endocrine system
    respiratory system
    nervous system
    set of connective tissues
    sensory organ
    reproductive system
    musculoskeletal system
    integumental system
    trunk
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1 (1/51) (1/1)
Brain 2 (6/485)
Dorsal root ganglion 1 (1/47)
Ear 2 (1/485) (1/3)
Embryo 2 (1/485) (3/3)
Eye 2 (1/485) (3/3)
Foot 2 (1/485) (2/3)
Forebrain 2 (1/485)
Forelimb 2 (1/485) (3/3)
Fronto-nasal process 1 (1/48) Image Only
Hand 2 (1/485) (2/3)
Head 2 (5/485) (3/3)
Heart 2 (1/485)
Hindbrain 2 (6/485)
Hindlimb 2 (1/485) (3/3)
Liver 2 (1/485)
Lung 2 (1/485)
Mandibular process 2 (1/485)
Maxillary process 2 (1/485) (1/3)
Midbrain 2 (1/485)
Nose 1 (1/51) (1/1)
Oral cavity 2 (1/485)
Rib pre-cartilage condensation 1 (1/46) (1/1)
Skin 2 (1/485) (1/3)
Spinal cord 1 (1/50)
Tail 2 (1/485) (3/3)
Tail somite 2 (1/485)


Associated Images

Associated Images
  • Echo: M-Mode Images
    32 Images
  • Embryo LacZ: LacZ images wholemount
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    21 Images
  • X-ray: XRay Images Lateral Orientation
    21 Images
  • X-ray: XRay Images Dorso Ventral
    21 Images
  • X-ray: XRay Images Skull Lateral Orientation
    10 Images
  • X-ray: XRay Images Forepaw
    10 Images
  • Electroretinography 2: Rod and cone PDF
    4 Images
  • Adult LacZ: LacZ Images Wholemount
    14 Images
  • Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
    4 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Fgf9tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Fgf9tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene