Gene: Cst3

Order

Name cystatin C

Synonyms CysC

Status ES CellsMice
tm1b
Mice
tm1a
phenotype data available

Links MGI:102519    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Cst3

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Cst3 data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal seminal vesicle morphology Cst3tm1b(EUCOMM)Wtsi HET Male postnatal 0.0
preweaning lethality, complete penetrance Cst3tm1b(EUCOMM)Wtsi HOM Female Male n/a 0.0
small superior vagus ganglion Cst3tm1b(EUCOMM)Wtsi HET Female postnatal 0.0

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (2/415) (3/4)
Aorta 2 No
Blood 0 No
Bone marrow 0 No (1/2)
Brain 2 No
Brainstem 2 No
Brown adipose tissue 0 No (1/2)
Cartilage tissue 2 No (1/4)
Cecum 0 No (12/383) (1/2)
Cerebellum 2 No (1/4)
Cerebral cortex 2 No
Chest bone 0 No
Colon 0 No (12/127) (1/2)
Diaphragm 0 No (1/2)
Duodenum 0 No (2/127)
Epididymis 0 No (18/134) (1/2)
Esophagus 2 No (7/415)
Eye 2 No (1/4)
Gall bladder 0 No
Gonadal fat pad 0 No (1/2)
Harderian gland 0 No (1/2)
Heart 2 No (2/4)
Hindlimb 0 No
Hippocampus 2 No
Hypothalamus 2 No
Ileum 0 No (14/127) (1/2)
Jejunum 0 No (6/127) (1/2)
Kidney 2 No (18/584) (3/4)
Large intestine 2 No (10/584)
Liver 2 No (3/4)
Lower urinary tract 2 No (2/4)
Lung 2 No (3/4)
Lymph node 2 No
Mammary gland 2 No
Mesenteric lymph node 0 No (1/2)
Mesenteric adipose tissue 0 No (1/2)
Midbrain 0 No (1/2)
Olfactory lobe 2 No (1/4)
Ovary 2 No (1/584)
Oviduct 2 No (1/4)
Pancreas 2 No (5/584) (3/4)
Parathyroid gland 0 No
Parotid gland 0 No
Penis 0 No (1/2)
Peripheral nervous system 2 No
Peyer's patch 2 No
Pituitary gland 2 No
Prostate gland 2 No (12/584) (2/4)
Quadriceps 0 No (1/2)
Sciatic nerve 0 No (1/2)
Skeletal muscle 2 No
Skin 2 No (3/4)
Small intestine 2 No (9/584)
Spinal cord 2 No (1/4)
Spleen 2 No (2/584) (1/4)
Stomach 2 No (12/584) (3/4)
Stomach pyloric region 0 No
Striatum 2 No
Sublingual gland 0 No (1/2)
Submandibular gland 0 No (2/132) (1/2)
Testis 2 No (2/584) (1/4)
Thymus 2 No (1/4)
Thyroid gland 2 No (15/584) (1/4)
Tongue 0 No (5/127) (1/2)
Trachea 2 No
Trigeminal V nerve 0 No
Urinary bladder 0 No (1/2)
Uterus 2 No (1/4)
Vagina 0 No
Vas deferens 0 No (15/388)
Vascular system 2 No (2/4)
Vesicular gland 0 No (1/2)
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    limb
    digestive system
    cardiovascular system
    set of connective tissues reproductive system adipose tissue
    musculoskeletal system
    trunk
    postnatal mouse
    nervous system sensory organ immune system exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2 (1/51) (2/2)
Brain 5 (6/485) (2/9)
Central nervous system ganglion 2 (1/51) (2/2)
Ear 5 (1/485) (2/9)
Embryo 5 (1/485) (2/9)
Eye 5 (1/485) (2/9)
Foot 5 (1/485) (2/9)
Forebrain 5 (1/485) (2/9)
Forelimb 5 (1/485) (2/9)
Gut 2 (1/50) (2/2)
Hand 5 (1/485) (2/9)
Head 5 (5/485) (2/9)
Heart 5 (1/485) (2/9)
Hindbrain 5 (6/485) (2/9)
Hindlimb 5 (1/485) (2/9)
Liver 5 (1/485) (2/9)
Lung 5 (1/485) (2/9)
Mandibular process 5 (1/485) (2/9)
Maxillary process 5 (1/485) (2/9)
Midbrain 5 (1/485) (2/9)
Nose 2 (1/51) (2/2)
Oral cavity 5 (1/485) (2/9)
1 (7/25) (1/1)
Skeleton 2 (1/51) (2/2)
Skin 5 (1/485) (2/9)
Spinal cord 2 (1/50) (2/2)
Tail 5 (1/485) (2/9)
Tail somite 5 (1/485) (2/9)
Trachea 2 (1/50) (2/2)
Urinary system 2 (1/50) (2/2)


Associated Images

Associated Images
  • Adult LacZ: LacZ Images Section
    13 Images
  • Embryo LacZ: LacZ images wholemount
    28 Images

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Cst3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Fixed Tissue
Cst3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Cst3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette)
Vector
Gene