Phenotype: decreased red blood cell distribution width

Definition lower than normal coefficient of variance (reference range) of the red blood cell volume for an organism

Synonyms
  • low red blood cell distribution width
  • low red blood cell distribution width
  • reduced red blood cell distribution width
  • reduced red blood cell distribution width
  • reduced erythrocyte distribution width
  • reduced red blood cell size variability
  • decreased red blood cell size variability
  • reduced RDW
  • decreased erythrocyte distribution width
  • low RDW
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MP browserMP:0010068

Phenotype associations stats

1.87% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased red blood cell distribution width (57/3043)

1.45% females (43/2967) 1.77% males (53/2997)



Gene variants with decreased red blood cell distribution width

Total number of significant genotype-phenotype associations: 96

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Glra2
Glra2tm1b(KOMP)Wtsi
HEM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.62E-10
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 3.14E-9
Becn1
Becn1tm1b(KOMP)Wtsi
HET Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 5.41E-9
Synj1
Synj1tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.49E-8
Dicer1
Dicer1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.68E-8
Atl2
Atl2tm2b(EUCOMM)Hmgu
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 3.8E-8
Chchd10
Chchd10em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 2.64E-7
Ints12
Ints12tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 3.72E-7
Fbxw13
Fbxw13em2(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 4.87E-7
Aars2
Aars2tm1(KOMP)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.44E-7
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 5.55E-7
Pard3
Pard3tm1b(KOMP)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 7.95E-7
Cdca7l
Cdca7lem1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 8.27E-7
Trappc1
Trappc1em1(IMPC)Mbp
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 9.99E-7
Wfdc11
Wfdc11em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 1.47E-6
Flnb
Flnbtm1b(KOMP)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.55E-6
Emp1
Emp1em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 1.84E-6
Prr9
Prr9em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 2.15E-6
Aig1
Aig1em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 2.24E-6
Fam53b
Fam53btm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 2.59E-6
Psd2
Psd2em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 3.43E-6
Ctr9
Ctr9tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 3.72E-6
C8b
C8btm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 4.11E-6
Smg6
Smg6em1(IMPC)Mbp
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 5.5E-6
Avpi1
Avpi1tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 5.67E-6
Cdc42ep3
Cdc42ep3em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 6.15E-6
Gpr155
Gpr155em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 6.58E-6
Ptgdr
Ptgdrtm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 8.11E-6
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 8.92E-6
Fbxl2
Fbxl2em2(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 9.27E-6
Ndufb9
Ndufb9tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 1.24E-5
Ddost
Ddosttm1.1(KOMP)Vlcg
HET Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 1.58E-5
Slc25a30
Slc25a30tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.61E-5
Fntb
Fntbtm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 1.63E-5
Gfpt1
Gfpt1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.68E-5
Mtmr7
Mtmr7em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 2.01E-5
Slc15a3
Slc15a3tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.04E-5
Ramp1
Ramp1tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.07E-5
Plac9a
Plac9atm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.2E-5
Chd1
Chd1tm1b(KOMP)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 2.63E-5
Nav3
Nav3em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 3.22E-5
Brcc3
Brcc3em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 3.92E-5
Ptchd3
Ptchd3em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 4.37E-5
Trim25
Trim25tm2b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 4.47E-5
Sdc2
Sdc2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 4.5E-5
Vps13a
Vps13atm1b(EUCOMM)Wtsi
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 5.19E-5
Ube2e1
Ube2e1em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.34E-5
Dusp27
Dusp27em1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 5.45E-5
Ufm1
Ufm1em1(IMPC)Marc
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 6.14E-5
Ints6l
Ints6lem1(IMPC)Marc
HEM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 6.19E-5
Pcx
Pcxtm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.33E-5
Trim37
Trim37em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 6.54E-5
Cyb561a3
Cyb561a3tm2b(EUCOMM)Hmgu
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 6.63E-5
Pdlim1
Pdlim1em1(IMPC)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 7.33E-5
Cand1
Cand1em1(IMPC)Mbp
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 7.61E-5
Kif3b
Kif3btm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 9.65E-5
Faf2
Faf2em1(IMPC)Mbp
HET Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 1.0E-4

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