Phenotype: decreased red blood cell distribution width

Definition lower than normal coefficient of variance (reference range) of the red blood cell volume for an organism

Synonyms
  • low red blood cell distribution width
  • low red blood cell distribution width
  • reduced red blood cell distribution width
  • reduced red blood cell distribution width
  • reduced erythrocyte distribution width
  • reduced red blood cell size variability
  • decreased red blood cell size variability
  • reduced RDW
  • decreased erythrocyte distribution width
  • low RDW
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Phenotype associations stats

1.37% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased red blood cell distribution width (40/2910)

0.92% females (26/2815) 1.30% males (37/2847)



Gene variants with decreased red blood cell distribution width

Total number of significant genotype-phenotype associations: 63

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Glra2
Glra2tm1b(KOMP)Wtsi
HEM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.52E-10
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 3.14E-9
Becn1
Becn1tm1b(KOMP)Wtsi
HET Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 1.12E-8
Dicer1
Dicer1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.68E-8
Synj1
Synj1tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.92E-8
Atl2
Atl2tm2b(EUCOMM)Hmgu
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 4.79E-8
Ints12
Ints12tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 3.87E-7
Fbxw13
Fbxw13em2(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.07E-7
Aars2
Aars2tm1(KOMP)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.36E-7
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 5.55E-7
Pard3
Pard3tm1b(KOMP)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 8.48E-7
Wfdc11
Wfdc11em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 1.48E-6
Flnb
Flnbtm1b(KOMP)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.59E-6
Fam53b
Fam53btm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 3.0E-6
Ctr9
Ctr9tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 3.72E-6
Ufm1
Ufm1em1(IMPC)Marc
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 4.03E-6
C8b
C8btm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 4.21E-6
Avpi1
Avpi1tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 5.67E-6
Fbxl2
Fbxl2em2(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 9.16E-6
Chd1
Chd1tm1b(KOMP)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 1.43E-5
Ndufb9
Ndufb9tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 1.48E-5
Gfpt1
Gfpt1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.49E-5
Ddost
Ddosttm1.1(KOMP)Vlcg
HET Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 1.58E-5
Slc25a30
Slc25a30tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.61E-5
Fntb
Fntbtm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 1.65E-5
Slc15a3
Slc15a3tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.05E-5
Ramp1
Ramp1tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.11E-5
Plac9a
Plac9atm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.24E-5
Sdc2
Sdc2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 3.83E-5
Brcc3
Brcc3em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 3.86E-5
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 4.26E-5
Trim25
Trim25tm2b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 4.47E-5
Vps13a
Vps13atm1b(EUCOMM)Wtsi
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 5.19E-5
Cyb561a3
Cyb561a3tm2b(EUCOMM)Hmgu
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 5.26E-5
Ube2e1
Ube2e1em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.49E-5
Ints6l
Ints6lem1(IMPC)Marc
HEM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 6.43E-5
Trim37
Trim37em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 6.7E-5
Pcx
Pcxtm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.78E-5
Pdlim1
Pdlim1em1(IMPC)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 7.33E-5
Kif3b
Kif3btm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 9.65E-5

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