Phenotype: decreased red blood cell distribution width

Definition lower than normal coefficient of variance (reference range) of the red blood cell volume for an organism

Synonyms
  • low red blood cell distribution width
  • low red blood cell distribution width
  • reduced red blood cell distribution width
  • reduced red blood cell distribution width
  • reduced erythrocyte distribution width
  • reduced red blood cell size variability
  • decreased red blood cell size variability
  • reduced RDW
  • decreased erythrocyte distribution width
  • low RDW
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Phenotype associations stats

1.98% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased red blood cell distribution width (43/2177)

1.30% females (28/2150) 1.79% males (39/2173)



Gene variants with decreased red blood cell distribution width

Total number of significant genotype-phenotype associations: 67

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Glra2
Glra2tm1b(KOMP)Wtsi
HEM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.62E-10
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.02E-9
Dicer1
Dicer1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.28E-8
Cep55
Cep55em2Tcp
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 1.36E-7
Ints12
Ints12tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 3.72E-7
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 4.13E-7
Aars2
Aars2tm1(KOMP)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 4.18E-7
Fbxw13
Fbxw13em2Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.15E-7
Pard3
Pard3tm1b(KOMP)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 7.95E-7
Wfdc11
Wfdc11em1Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 1.31E-6
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 1.32E-6
Flnb
Flnbtm1b(KOMP)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.55E-6
Fam53b
Fam53btm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 2.32E-6
Becn1
Becn1tm1b(KOMP)Wtsi
HET Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 2.74E-6
Ctr9
Ctr9tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 4.05E-6
C8b
C8btm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 4.11E-6
Fntb
Fntbtm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.54E-6
Avpi1
Avpi1tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 5.67E-6
Fbxl2
Fbxl2em2Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 9.21E-6
Slc25a30
Slc25a30tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.15E-5
Xbp1
Xbp1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.26E-5
Pld5
Pld5tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.42E-5
Gfpt1
Gfpt1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.55E-5
Slc15a3
Slc15a3tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.04E-5
Ramp1
Ramp1tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.07E-5
Plac9a
Plac9atm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.2E-5
Sdc2
Sdc2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 2.42E-5
Kif3b
Kif3btm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 2.8E-5
Ufm1
Ufm1em1Marc
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 3.04E-5
Atl2
Atl2tm2b(EUCOMM)Hmgu
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 3.38E-5
Brd9
Brd9em1Tcp
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 3.42E-5
Xkr5
Xkr5tm1b(KOMP)Mbp
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 3.47E-5
Ints6l
Ints6lem1Marc
HEM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 3.94E-5
Brcc3
Brcc3em1Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.02E-5
Ube2e1
Ube2e1em1Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.1E-5
Trim37
Trim37em1Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.32E-5
Kdm8
Kdm8tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.27E-5
Oplah
Oplahtm1b(KOMP)Wtsi
HOM Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 7.01E-5
Cyb561a3
Cyb561a3tm2b(EUCOMM)Hmgu
HOM Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 7.12E-5
Prdm5
Prdm5em2Tcp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 7.24E-5
Fxyd3
Fxyd3tm1a(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 8.78E-5
Vps13a
Vps13atm1b(EUCOMM)Wtsi
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 8.88E-5
Radil
Radilem1Tcp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 8.99E-5

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