Phenotype: decreased red blood cell distribution width

Definition lower than normal coefficient of variance (reference range) of the red blood cell volume for an organism

Synonyms
  • low red blood cell distribution width
  • low red blood cell distribution width
  • reduced red blood cell distribution width
  • reduced red blood cell distribution width
  • reduced erythrocyte distribution width
  • reduced red blood cell size variability
  • decreased red blood cell size variability
  • reduced RDW
  • decreased erythrocyte distribution width
  • low RDW
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Phenotype associations stats

1.61% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased red blood cell distribution width (46/2852)

1.12% females (31/2769) 1.50% males (42/2798)



Gene variants with decreased red blood cell distribution width

Total number of significant genotype-phenotype associations: 73

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Glra2
Glra2tm1b(KOMP)Wtsi
HEM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.38E-10
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 3.05E-9
Becn1
Becn1tm1b(KOMP)Wtsi
HET Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 5.68E-9
Dicer1
Dicer1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.68E-8
Synj1
Synj1tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.17E-8
Atl2
Atl2tm2b(EUCOMM)Hmgu
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 6.25E-8
Aars2
Aars2tm1(KOMP)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 1.66E-7
Fbxw13
Fbxw13em2(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 3.83E-7
Ints12
Ints12tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 4.0E-7
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 5.45E-7
Wfdc11
Wfdc11em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 7.99E-7
Pard3
Pard3tm1b(KOMP)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 9.23E-7
Flnb
Flnbtm1b(KOMP)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.62E-6
Chd1
Chd1tm1b(KOMP)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 2.35E-6
Trim37
Trim37em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 2.36E-6
Lpcat1
Lpcat1tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.5E-6
Ap4e1
Ap4e1em2(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 2.66E-6
Fntb
Fntbtm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 3.46E-6
Ctr9
Ctr9tm1b(EUCOMM)Wtsi
HET Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 3.58E-6
Fam53b
Fam53btm1b(EUCOMM)Hmgu
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 4.25E-6
C8b
C8btm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 4.27E-6
Fbxl2
Fbxl2em2(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 4.83E-6
Avpi1
Avpi1tm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 5.67E-6
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 1.03E-5
Ndufb9
Ndufb9tm1b(EUCOMM)Hmgu
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 1.22E-5
Ptgdr
Ptgdrtm1.1(KOMP)Vlcg
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 1.37E-5
Pld5
Pld5tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.42E-5
Gfpt1
Gfpt1tm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.55E-5
Ddost
Ddosttm1.1(KOMP)Vlcg
HET Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width TCP | IMPC 1.58E-5
Slc25a30
Slc25a30tm1a(EUCOMM)Wtsi
HOM Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 1.67E-5
Slc15a3
Slc15a3tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 1.99E-5
Ramp1
Ramp1tm1b(EUCOMM)Wtsi
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.15E-5
Plac9a
Plac9atm1b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 2.25E-5
Cyb561a3
Cyb561a3tm2b(EUCOMM)Hmgu
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 3.34E-5
Brcc3
Brcc3em1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 3.68E-5
Trim25
Trim25tm2b(EUCOMM)Hmgu
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 4.18E-5
Sdc2
Sdc2tm1b(KOMP)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width HMGU | IMPC 4.32E-5
Aoah
Aoahem1(IMPC)Mbp
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width UC Davis | IMPC 5.03E-5
Vps13a
Vps13atm1b(EUCOMM)Wtsi
HOM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 5.05E-5
Ints6l
Ints6lem1(IMPC)Marc
HEM Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 5.54E-5
Pcx
Pcxtm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MRC Harwell | IMPC 5.71E-5
Ufm1
Ufm1em1(IMPC)Marc
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 6.14E-5
Snx25
Snx25tm1b(KOMP)Wtsi
HET Female postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 6.18E-5
Pdlim1
Pdlim1em1(IMPC)Wtsi
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 7.32E-5
Hnrnpr
Hnrnprem1(IMPC)Marc
HOM Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width MARC | IMPC 8.48E-5
Kif3b
Kif3btm1b(EUCOMM)Wtsi
HET Female Male postnatal decreased red blood cell distribution width Hematology | Red blood cell distribution width WTSI | IMPC 9.12E-5

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