Phenotype: impaired glucose tolerance

Definition
less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals
Synonyms
poor glucose tolerance,  glucose intolerance,  reduced glucose tolerance
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with impaired glucose tolerance

Total number of significant genotype-phenotype associations: 215

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Cacna2d1
Cacna2d1em1(IMPC)Mbp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
0.00
Abcc8
Abcc8em1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.03×10-20
Kcnj11
Kcnj11tm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
2.99×10-20
Ccnd2
Ccnd2tm1b(KOMP)Mbp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
3.92×10-18
Gh
Ghtm1.1(KOMP)Vlcg
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
5.74×10-18
Nbr1
Nbr1tm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
7.42×10-18
Cpe
Cpetm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
1.88×10-16
Cacnb2
Cacnb2tm1.1(KOMP)Vlcg
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
2.85×10-14
Pdx1
Pdx1tm1b(EUCOMM)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
3.90×10-14
Gck
Gckem1(IMPC)H
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
7.48×10-14
Col4a5
Col4a5tm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
7.78×10-14
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
1.32×10-13
Dusp8
Dusp8em1(IMPC)Mbp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
3.41×10-13
Tanc2
Tanc2em1(IMPC)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
2.47×10-12
Steap3
Steap3tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
2.80×10-11
Agl
Agltm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
3.31×10-11
Fgb
Fgbtm1.1(KOMP)Vlcg
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
3.28×10-10
Ube4a
Ube4aem1(IMPC)Tcp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
3.67×10-10
Ccdc25
Ccdc25em1(IMPC)Mbp
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
4.08×10-10
Sec24d
Sec24dem1(IMPC)Rbrc
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
RBRC
IMPC
5.79×10-10
Surf4
Surf4em1(IMPC)J
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.36×10-09
Mtmr3
Mtmr3tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.93×10-09
Trappc9
Trappc9tm1a(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
2.11×10-09
Zfp664
Zfp664tm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
3.53×10-09
Ncoa3
Ncoa3tm1b(EUCOMM)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
9.47×10-09
Gnl1
Gnl1em1(IMPC)Tcp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
1.48×10-08
Zfp787
Zfp787em1(IMPC)J
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.56×10-08
Ing5
Ing5em1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.73×10-08
Fzd3
Fzd3tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
3.82×10-08
Igsf8
Igsf8em1(IMPC)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
3.96×10-08
Ghrh
Ghrhtm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
4.32×10-08
Fbxl9
Fbxl9em1(IMPC)Bay
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
6.95×10-08
Meis3
Meis3tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
CCP-IMG
IMPC
9.47×10-08
Hyal6
Hyal6em1(IMPC)H
HOM   Late adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
9.85×10-08
Rabl2
Rabl2tm1.1(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
1.37×10-07
Nt5c1b
Nt5c1btm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.72×10-07
Car13
Car13tm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
1.95×10-07
Gimap6
Gimap6tm1a(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
2.31×10-07
Bnip3
Bnip3em1(IMPC)Mbp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
2.33×10-07
Ilrun
Ilrunem1(IMPC)Tcp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
2.52×10-07
Zbtb48
Zbtb48em1(IMPC)Mbp
HOM Late adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
2.82×10-07
Il12b
Il12bem1(IMPC)H
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
3.17×10-07
Foxo3
Foxo3tm1.1(KOMP)Vlcg
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.21×10-07
Gpr83
Gpr83em1(IMPC)Ccpcz
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
CCP-IMG
IMPC
3.33×10-07
Slc12a5
Slc12a5em1(IMPC)Mbp
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
3.99×10-07
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
4.24×10-07
Brcc3dc
Brcc3dcem1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.43×10-07
Prdm8
Prdm8em1(IMPC)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
CCP-IMG
IMPC
4.53×10-07
Galt
Galtem1(IMPC)H
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
4.91×10-07
Acadvl
Acadvlem1(IMPC)H
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
5.76×10-07
Nedd4
Nedd4tm2b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
6.15×10-07
Stxbp1
Stxbp1tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
6.25×10-07
Prkab1
Prkab1em1(IMPC)J
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
6.38×10-07
Dpm2
Dpm2tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
6.88×10-07
Nhlh2
Nhlh2em1(IMPC)Mbp
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
7.07×10-07
Prdm14
Prdm14tm1a(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
7.19×10-07
Ttll10
Ttll10tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
8.53×10-07
Trpm1
Trpm1tm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
8.54×10-07
Mmgt2
Mmgt2tm1b(EUCOMM)Wtsi
HOM   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
8.66×10-07
Nacc1
Nacc1em1(IMPC)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
9.26×10-07
Gad2
Gad2tm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
1.01×10-06
Slc26a2
Slc26a2em1(IMPC)Bay
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
1.08×10-06
Shld1
Shld1em1(IMPC)Mbp
HOM Late adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
1.33×10-06
Iqsec3
Iqsec3tm3b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
2.10×10-06
Shh
Shhtm1b(EUCOMM)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
2.70×10-06
Rigi
Rigiem1(IMPC)Mbp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
2.71×10-06
Usp30
Usp30tm2b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
2.83×10-06
Farsa
Farsatm2a(EUCOMM)Wtsi
HET Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
2.97×10-06
Pald1
Pald1em1(IMPC)Kmpc
HOM   Late adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
KMPC
IMPC
3.12×10-06
Ppp4r3b
Ppp4r3btm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
3.19×10-06
Herc1
Herc1em3(IMPC)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
3.59×10-06
Cs
Cstm1.1(KOMP)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
3.79×10-06
Slc6a2
Slc6a2tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
3.81×10-06
Iqcf1
Iqcf1em1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.89×10-06
Mettl18
Mettl18em1(IMPC)J
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.36×10-06
Cpd
Cpdem1(IMPC)J
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.37×10-06
Pard6a
Pard6atm1.1(KOMP)Vlcg
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.53×10-06
Pcm1
Pcm1em1(IMPC)Tcp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
4.56×10-06
Eif4g2
Eif4g2tm1b(KOMP)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.68×10-06
Acox3
Acox3em1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.84×10-06
Prdm4
Prdm4tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
5.16×10-06
Tbccd1
Tbccd1tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
5.48×10-06
Lyar
Lyarem1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
5.49×10-06
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
5.61×10-06
Pole2
Pole2em1(IMPC)Mbp
HET Late adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
6.35×10-06
Plaat3
Plaat3em1(IMPC)Tcp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
6.45×10-06
Celf4
Celf4tm1a(EUCOMM)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
6.71×10-06
Apoc4
Apoc4tm1.1(KOMP)Mbp
HOM   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
6.84×10-06
Fhip2a
Fhip2aem1(IMPC)J
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
6.90×10-06
Mir129-2
Mir129-2em1(IMPC)Kmpc
HOM Late adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
KMPC
IMPC
7.02×10-06
Cpgi15497
Cpgi15497tm1.1(NCC)WCS
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
7.48×10-06
Tle4
Tle4em1(IMPC)Mbp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
7.75×10-06
Dtx4
Dtx4em1(IMPC)Ccpcz
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
CCP-IMG
IMPC
7.86×10-06
Rfx6
Rfx6tm1.1(KOMP)Vlcg
HET   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
7.95×10-06
Prss35
Prss35em1(IMPC)Ccpcz
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
CCP-IMG
IMPC
8.18×10-06
Mrap2
Mrap2tm1a(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
8.22×10-06
Kat2b
Kat2bem1(IMPC)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
9.33×10-06
Dpp8
Dpp8em1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
9.43×10-06
Sirpa
Sirpatm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
9.43×10-06
Knl1
Knl1tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
9.49×10-06
Kdm3a
Kdm3aem1(IMPC)Mbp
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
9.52×10-06
Emsy
Emsyem1(IMPC)Ccpcz
HET Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
CCP-IMG
IMPC
9.72×10-06
Gpr15
Gpr15em1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
9.72×10-06
Depdc5
Depdc5tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
9.88×10-06
Exoc3l2
Exoc3l2em1(IMPC)J
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.03×10-05
Glp1r
Glp1rtm1b(KOMP)Mbp
HOM   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
1.04×10-05
Ccr9
Ccr9em1(IMPC)H
HOM Late adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
1.10×10-05
Cabp5
Cabp5tm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
1.17×10-05
Dync1h1
Dync1h1tm1dIcs
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
1.28×10-05
Lonrf2
Lonrf2em2(IMPC)H
HOM   Late adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
1.42×10-05
E2f3
E2f3tm1b(KOMP)Wtsi
HET Late adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
KMPC
IMPC
1.52×10-05
Pgm3
Pgm3em1(IMPC)Hmgu
HET   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
1.54×10-05
Grik4
Grik4em1(IMPC)Mbp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
1.65×10-05
Nrxn1
Nrxn1tm1b(KOMP)Wtsi
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
1.78×10-05
Insig1
Insig1em1(IMPC)Ccpcz
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
CCP-IMG
IMPC
1.86×10-05
Ggps1
Ggps1tm1b(EUCOMM)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
1.89×10-05
Slc25a18
Slc25a18tm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
KMPC
IMPC
1.90×10-05
Anapc7
Anapc7em1(IMPC)J
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
1.95×10-05
Odad3
Odad3tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
2.07×10-05
Rel
Reltm1b(EUCOMM)Wtsi
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
2.13×10-05
Slc20a2
Slc20a2tm1b(EUCOMM)Wtsi
HET   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
2.16×10-05
Trio
Trioem1(IMPC)H
HET Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
2.29×10-05
Il15
Il15tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
2.30×10-05
Mpp2
Mpp2tm1b(KOMP)Wtsi
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
2.30×10-05
Puf60
Puf60em1(IMPC)Bay
HET   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
2.36×10-05
Sh2b1
Sh2b1em1(IMPC)Ics
HET   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
2.50×10-05
Polr2f
Polr2ftm1e(EUCOMM)Wtsi
HET Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
2.53×10-05
Abcc5
Abcc5em1(IMPC)H
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
2.61×10-05
Fam83a
Fam83aem1(IMPC)J
HOM   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
2.62×10-05
Fstl1
Fstl1tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
2.63×10-05
2210408I21Rik
2210408I21Riktm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
2.64×10-05
Nisch
Nischtm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
2.67×10-05
Pax5
Pax5tm1b(EUCOMM)Wtsi
HET   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
2.67×10-05
Pclaf
Pclaftm1a(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
2.85×10-05
Golga3
Golga3tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
2.88×10-05
Ddi2
Ddi2tm1b(EUCOMM)Hmgu
HET   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
CCP-IMG
IMPC
2.94×10-05
Ctdspl
Ctdspltm1.1(KOMP)Mbp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
3.05×10-05
Dis3
Dis3tm1e.1(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
3.08×10-05
Gdi2
Gdi2tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
3.11×10-05
Commd9
Commd9tm1b(KOMP)Wtsi
HET   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
3.12×10-05
Cyp7b1
Cyp7b1tm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
3.26×10-05
Trim25
Trim25tm2b(EUCOMM)Hmgu
HOM   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
3.29×10-05
Bpifc
Bpifcem1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.31×10-05
Zfp462
Zfp462em1(IMPC)Tcp
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
3.40×10-05
Myo3a
Myo3atm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.54×10-05
Vps13b
Vps13bem1(IMPC)Tcp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
3.55×10-05
Pomc
Pomcem1(IMPC)Rbrc
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
RBRC
IMPC
3.70×10-05
Krtcap2
Krtcap2em1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.79×10-05
Swt1
Swt1em1(IMPC)J
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
3.85×10-05
Hpca
Hpcaem1(IMPC)H
HOM   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
3.98×10-05
Efr3b
Efr3bem1(IMPC)Mbp
HOM   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
4.27×10-05
Pigq
Pigqtm2b(EUCOMM)Wtsi
HET Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
4.31×10-05
Kifap3
Kifap3tm1a(KOMP)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
4.56×10-05
Nisch
Nischtm1b(EUCOMM)Hmgu
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
4.73×10-05
Gckr
Gckrem1(IMPC)H
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
4.81×10-05
Pwwp2b
Pwwp2bem1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
4.99×10-05
Vdac1
Vdac1tm1b(EUCOMM)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
5.14×10-05
Tulp3
Tulp3tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
5.14×10-05
Gramd2b
Gramd2bem1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
5.15×10-05
Pcdh8
Pcdh8em1(IMPC)H
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
5.19×10-05
Dhx29
Dhx29tm1.1(KOMP)Vlcg
HET   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
5.20×10-05
Grm3
Grm3tm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
5.25×10-05
Eef2kmt
Eef2kmttm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
5.67×10-05
Nr2c2
Nr2c2tm1b(EUCOMM)Wtsi
HET   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
5.85×10-05
Rufy2
Rufy2tm1a(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
5.86×10-05
Slc2a13
Slc2a13em1(IMPC)Mbp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
6.34×10-05
Capn11
Capn11tm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
6.49×10-05
Pigc
Pigcem1(IMPC)J
HET   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
6.53×10-05
Marchf6
Marchf6tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
CCP-IMG
IMPC
6.73×10-05
Dgcr2
Dgcr2tm1b(EUCOMM)Wtsi
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
7.06×10-05
Gpx3
Gpx3tm1b(KOMP)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
7.07×10-05
Dtnbp1
Dtnbp1tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
7.09×10-05
Chmp3
Chmp3tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
7.21×10-05
Ccdc116
Ccdc116tm1.1(KOMP)Vlcg
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
7.25×10-05
Eno3
Eno3em1(IMPC)Bay
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
7.31×10-05
Tigd3
Tigd3em1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
7.35×10-05
Syncrip
Syncriptm1b(EUCOMM)Hmgu
HET   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
7.60×10-05
Egfem1
Egfem1em1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
7.69×10-05
Sncb
Sncbtm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
7.70×10-05
Col14a1
Col14a1tm1b(KOMP)Wtsi
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
BCM
IMPC
7.76×10-05
Palm
Palmem1(IMPC)Wtsi
HOM   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
WTSI
IMPC
8.02×10-05
Ctbs
Ctbsem1(IMPC)J
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
8.04×10-05
Usp12
Usp12tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
8.22×10-05
Aak1
Aak1tm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
ICS
IMPC
8.41×10-05
Cln6
Cln6tm1b(EUCOMM)Hmgu
HOM   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
8.47×10-05
Terf2ip
Terf2ipem1(IMPC)Mbp
HOM   Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
UC Davis
IMPC
8.55×10-05
Rbms1
Rbms1tm1b(EUCOMM)Wtsi
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
8.72×10-05
Rnaset2b
Rnaset2btm1b(EUCOMM)Hmgu
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
8.88×10-05
Bltp1
Bltp1tm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
HMGU
IMPC
8.95×10-05
Mapkbp1
Mapkbp1tm1b(EUCOMM)Hmgu
HOM   Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
9.08×10-05
Coq8b
Coq8btm1b(EUCOMM)Hmgu
HET Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
9.21×10-05
Aqp1
Aqp1tm1b(EUCOMM)Wtsi
HOM Early adult impaired glucose tolerance Initial response to glucose challenge
Intraperitoneal glucose tolerance test (IPGTT)
MRC Harwell
IMPC
9.39×10-05
Pgbd5
Pgbd5em1(IMPC)Tcp
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
TCP
IMPC
9.60×10-05
Serinc2
Serinc2em1(IMPC)J
HOM Early adult impaired glucose tolerance Area under glucose response curve
Intraperitoneal glucose tolerance test (IPGTT)
JAX
IMPC
9.89×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

2.70% of tested genes with null mutations on a B6N genetic background have a phenotype association to impaired glucose tolerance (192/7120)

0.86% females (63/7342) 1.55% males (114/7352)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter