Phenotype: thrombocytopenia

Definition fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation

Synonyms
  • reduced platelet count
  • reduced platelet count
  • thrombopenia
  • thrombopenia
  • decreased thrombocyte number
  • decreased platelet cell number
  • decreased platelet count
Show more
Related
Synonyms
  • Amegakaryocytic thrombocytopenia
  • Amegakaryocytic thrombocytopenia
  • Aplastic anemia
  • Aplastic anemia
  • Autoimmune thrombocytopenia
  • Macrothrombocytopenia
  • Congenital thrombocytopenia
  • Intermittent thrombocytopenia
  • absent platelets
  • Aplastic anemia
  • Pancytopenia
  • Neonatal alloimmune thrombocytopenia
  • Heparin-induced thrombocytopenia
  • Post-transfusion thrombocytopenia
  • pancytopenia
Show more

MP browserMP:0003179

Phenotype associations stats

1.78% of tested genes with null mutations on a B6N genetic background have a phenotype association to thrombocytopenia (70/3927)

1.34% females (52/3885) 1.71% males (67/3908)

Select a parameter    



Gene variants with thrombocytopenia

Total number of significant genotype-phenotype associations: 124

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value Data
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 4.44E-21
Crlf3
Crlf3em1(IMPC)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 1.3E-17
Lyn
Lyntm1b(EUCOMM)Hmgu
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 3.74E-16
Nbeal2
Nbeal2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 1.29E-14
Osm
Osmtm1b(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 1.06E-12
Crlf3
Crlf3tm1a(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Haematology test | Platelets-count WTSI | EuroPhenome 3.5E-12
Emc10
Emc10tm1b(EUCOMM)Wtsi
HOM Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 4.24E-12
Ly6g6d
Ly6g6dtm1b(EUCOMM)Hmgu
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count HMGU | IMPC 9.03E-12
Lepr
Leprtm1b(EUCOMM)Wtsi
HOM Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 1.94E-11
Crlf3
Crlf3tm1b(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 4.82E-11
Txnip
Txniptm1b(EUCOMM)Hmgu
HOM Female postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 5.26E-11
Fbxo11
Fbxo11Jf
HET Female Male postnatal thrombocytopenia Haematology | Platelets count MRC Harwell | EuroPhenome 8.24E-11
Knstrn
Knstrntm1b(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count ICS | IMPC 6.0E-10
Fbxo36
Fbxo36tm1b(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count MARC | IMPC 6.78E-10
Gp1bb
Gp1bbtm1.1(KOMP)Vlcg
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count UC Davis | IMPC 7.33E-10
Ghrhr
Ghrhrtm1.1(KOMP)Vlcg
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 2.46E-9
Sgms1
Sgms1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 6.43E-9
Bcl3
Bcl3tm1b(EUCOMM)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 1.33E-8
Pld3
Pld3tm1e(EUCOMM)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 1.4E-8
Elmod1
Elmod1tm1a(EUCOMM)Hmgu
HOM Female Male postnatal thrombocytopenia Haematology | Platelets count MRC Harwell | MGP 1.43E-8
Tbc1d22a
Tbc1d22atm1b(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 3.97E-8
Bin2
Bin2em1(IMPC)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 4.24E-8
Sept5
Sept5tm1b(EUCOMM)Hmgu
HET Female Male postnatal thrombocytopenia Hematology | Platelet count RBRC | IMPC 5.2E-8
Exosc8
Exosc8tm1.1(KOMP)Vlcg
HET Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 6.93E-8
Ppp2r2b
Ppp2r2btm1a(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Haematology test | Platelets-count WTSI | EuroPhenome 1.3E-7
Usp38
Usp38tm1b(EUCOMM)Hmgu
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 1.55E-7
Arrb1
Arrb1tm1b(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 1.59E-7
Bbs5
Bbs5tm1b(EUCOMM)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 4.27E-7
Mllt3
Mllt3tm1b(EUCOMM)Hmgu
HET Female Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 7.37E-7
Aspm
Aspmtm1a(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 9.06E-7
Ephx1
Ephx1
HOM Male postnatal thrombocytopenia Haematology | Platelets count ICS | EuroPhenome 1.23E-6
Tmem79
Tmem79tm1.1(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 1.41E-6
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Male postnatal thrombocytopenia Hematology | Platelet count HMGU | IMPC 1.82E-6
Gp9
Gp9tm1.1(KOMP)Vlcg
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count UC Davis | IMPC 2.06E-6
Ppp1r9b
Ppp1r9btm1.1(KOMP)Vlcg
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 2.13E-6
Hsf2bp
Hsf2bptm1a(EUCOMM)Hmgu
HET Male postnatal thrombocytopenia Haematology | Platelets count HMGU | EuroPhenome 3.17E-6
Smurf2
Smurf2tm1b(EUCOMM)Wtsi
HET Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 3.32E-6
Clpp
Clpptm1a(EUCOMM)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 3.55E-6
Setdb2
Setdb2tm1a(KOMP)Wtsi
HOM Male postnatal thrombocytopenia Haematology | Platelets count HMGU | EuroPhenome 4.57E-6
Cfi
Cfitm1b(EUCOMM)Hmgu
HOM Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 4.72E-6
Dffb
Dffbem1(IMPC)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 4.87E-6
Htr1b
Htr1btm1.1(KOMP)Vlcg
HET Female Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 8.0E-6
Tmem203
Tmem203em1(IMPC)H
HOM Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 8.51E-6
Trmt1l
Trmt1lGt(W027A02)Wrst
HOM Male postnatal thrombocytopenia Haematology (GMC) | Platelet HMGU | EuroPhenome 9.41E-6
Elmod1
Elmod1tm1b(EUCOMM)Hmgu
HOM Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 9.61E-6
Tubb2a
Tubb2aem1(IMPC)J
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 9.63E-6
Lsm14a
Lsm14atm1b(KOMP)Wtsi
HET Male postnatal thrombocytopenia Hematology | Platelet count MARC | IMPC 1.15E-5
Kdm5b
Kdm5bem1(IMPC)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 1.35E-5
Lamc3
Lamc3tm1a(KOMP)Wtsi
HOM Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 1.49E-5
Cyp3a59
Cyp3a59em1(IMPC)Marc
HET Female Male postnatal thrombocytopenia Hematology | Platelet count MARC | IMPC 1.56E-5
Dennd2d
Dennd2dtm2b(KOMP)Mbp
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 1.73E-5
Rwdd1
Rwdd1tm1b(KOMP)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 2.5E-5
Psph
Psphtm1.1(KOMP)Vlcg
HET Male postnatal thrombocytopenia Hematology | Platelet count TCP | IMPC 2.54E-5
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 2.87E-5
Rab11a
Rab11atm1b(KOMP)Wtsi
HET Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 4.25E-5
Tfap4
Tfap4tm1.1(KOMP)Vlcg
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count UC Davis | IMPC 4.64E-5
Mta1
Mta1tm1a(EUCOMM)Wtsi
HOM Female Male postnatal thrombocytopenia Haematology | Platelets count WTSI | EuroPhenome 4.97E-5
Phtf2
Phtf2tm1a(EUCOMM)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 5.07E-5
Arrdc1
Arrdc1tm1.1(KOMP)Vlcg
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 5.33E-5
Mir96
Mir96tm3.2(IMPC)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 5.78E-5
Dcun1d3
Dcun1d3em1(IMPC)Wtsi
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 6.43E-5
Acsl4
Acsl4tm1a(EUCOMM)Wtsi
HET Female postnatal thrombocytopenia Haematology test | Platelets-count WTSI | MGP 6.52E-5
Baiap2
Baiap2tm1b(KOMP)Wtsi
HET Male postnatal thrombocytopenia Hematology | Platelet count UC Davis | IMPC 7.11E-5
Cidec
Cidectm1a(EUCOMM)Wtsi
HOM Male postnatal thrombocytopenia Haematology | Platelets count HMGU | EuroPhenome 7.48E-5
Rasgrf1
Rasgrf1tm1bNarl
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count MRC Harwell | IMPC 7.67E-5
Kcnh3
Kcnh3tm1.1(KOMP)Vlcg
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 8.35E-5
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Male postnatal thrombocytopenia Hematology | Platelet count WTSI | IMPC 8.36E-5
Fntb
Fntbtm1b(EUCOMM)Hmgu
HET Female Male postnatal thrombocytopenia Hematology | Platelet count MARC | IMPC 8.59E-5
Atg4b
Atg4bem1(IMPC)Marc
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count MARC | IMPC 8.81E-5
Nae1
Nae1tm1b(EUCOMM)Wtsi
HET Female Male postnatal thrombocytopenia Hematology | Platelet count ICS | IMPC 8.82E-5
Cadm1
Cadm1tm1.2Brd
HOM Female Male postnatal thrombocytopenia Haematology | Platelets count WTSI | EuroPhenome 9.45E-5
Lypd2
Lypd2em1(IMPC)Marc
HOM Female Male postnatal thrombocytopenia Hematology | Platelet count MARC | IMPC 9.47E-5
Arrb2
Arrb2tm1.1(KOMP)Vlcg
HOM Female postnatal thrombocytopenia Hematology | Platelet count JAX | IMPC 9.49E-5

Download data as: TSV XLS