MP:0002544 (brachydactyly) | IMPC Phenotype Information | International Mouse Phenotyping Consortium

Phenotype: brachydactyly

Definition

abnormally short digits

Synonyms

short digits

of tested genes

significant genes

tested genes

Total number of significant genotype-phenotype associations: 9

Gene / Allele	Zygosity	Life Stage	Phenotype	Parameter	Phenotyping Center	P Value
Dnase1l2 Dnase1l2^{tm1(KOMP)Wtsi}	HOM	Early adult	brachydactyly	Brachydactyly X-ray	RBRC IMPC	1.43×10^-08
Furin Furin^{tm1b(EUCOMM)Wtsi}	HET	Early adult	brachydactyly	Brachydactyly X-ray	MRC Harwell IMPC	5.05×10^-08
Spry4 Spry4^{tm1b(KOMP)Mbp}	HOM	Early adult	brachydactyly	Brachydactyly X-ray	KMPC IMPC	6.61×10^-08
Dnase1l2 Dnase1l2^{tm1.1(KOMP)Wtsi}	HOM	Early adult	brachydactyly	Brachydactyly X-ray	TCP IMPC	9.31×10^-08
Gkn2 Gkn2^{tm1.1(KOMP)Vlcg}	HOM	Early adult	brachydactyly	Brachydactyly X-ray	UC Davis IMPC	1.26×10^-06
Mogs Mogs^{tm1(KOMP)Vlcg}	HET	Early adult	brachydactyly	Brachydactyly X-ray	BCM IMPC	4.92×10^-05

Download data as: TSV XLS

Procedure
X-ray
Combined SHIRPA and Dysmorphology
Dysmorphology
X-Ray

0.15% of tested genes with null mutations on a B6N genetic background have a phenotype association to brachydactyly (5/3239)

0.09% females (3/3233) 0.12% males (4/3233)

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