LOCUS       KO-first_condition_ready_89824:79714:77581_MGI:101920        22338 bp    dna     circular UNK 
DEFINITION  Mus musculus targeted KO-first, conditional ready, lacZ-tagged
            mutant vector Ap2a2 targeting project(s): 89824:79714:77581
ACCESSION   unknown
SOURCE      Mus musculus
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
            Sciurognathi; Muroidea; Muridae; Murinae; Mus.
COMMENT     cassette: L1L2_Bact_P
COMMENT     design_id: 170930
COMMENT     backbone: R3R4_pBR_DTA+_Bsd_amp
FEATURES             Location/Qualifiers
     misc_feature    29..152
                     /note="R4 gateway site"
     promoter        399..911
                     /note="PGK promoter"
     CDS             925..1581
                     /note="DTA"
     misc_feature    1706..1959
                     /note="BGH pA"
     promoter        2034..2100
                     /note="EM7 promoter"
     CDS             2101..2499
                     /note="BsdR"
     CDS             complement(4193..5053)
                     /note="AmpR"
     misc_feature    5272..5395
                     /note="R3 gateway site"
     misc_feature    5401..5408
                     /note="AsiSI"
     misc_feature    1..5433
                     /note="Synthetic Backbone"
     exon            9853..9995
                     /db_xref="ENSEMBL:ENSMUSE00000374230"
                     /rank="3"
                     /note="ENSMUSE00000374230"
     misc_feature    5434..10659
                     /note="5 arm"
     misc_feature    10687..10711
                     /note="B1 Gateway"
     misc_feature    10724..10771
                     /note="Frt"
     intron          10772..11646
                     /note="mouse En2 intron"
     misc_feature    11644..11646
                     /note="Splice Acceptor"
     exon            11647..11819
                     /note="mouse En2 exon"
     misc_feature    11831..12424
                     /note="ECMV IRES"
     gene            12425..15485
                     /gene="lacZ"
                     /note="lacZ"
     misc_feature    15524..15767
                     /note="SV40 polyadenylation site"
     misc_feature    15771..15804
                     /note="loxP"
     promoter        15831..16350
                     /note="human beta actin promoter"
     gene            16376..17170
                     /gene="NeoR"
                     /note="NeoR"
     misc_feature    17370..17611
                     /note="SV40 polyadenylation site"
     misc_feature    17628..17675
                     /note="Frt"
     misc_feature    17682..17715
                     /note="loxP"
     misc_feature    11661..11738
                     /note="FCHK std_gpr"
     misc_feature    17731..17751
                     /note="B2 Gateway"
     misc_feature    10660..17781
                     /note="Synthetic Cassette"
     exon            18137..18330
                     /db_xref="ENSEMBL:ENSMUSE00001084686"
                     /type="targeted"
                     /rank="4"
                     /note="target exon 1 ENSMUSE00001084686"
     misc_feature    17782..18525
                     /note="Critical Region"
     misc_feature    18549..18582
                     /note="Downstream LoxP"
     misc_feature    18526..18605
                     /note="synthetic loxP region"
     exon            21712..21841
                     /db_xref="ENSEMBL:ENSMUSE00000273061"
                     /rank="5"
                     /note="ENSMUSE00000273061"
     misc_feature    18606..22338
                     /note="3 arm"
ORIGIN      
        1 ccactggccg tcgttttaca ttaattaaca actttgtata gaaaagttga acgagaaacg
       61 taaaatgata taaatatcaa tatattaaat tagattttgc ataaaaaaca gactacataa
      121 tactgtaaaa cacaacatat ccagtcacta tggcggccgc aatcgggcag cgttgggtcc
      181 tggccacggg tgcgcatgat cgtgctcctg tcgttgagga cccggctagg ctggcggggt
      241 tgccttactg gttagcagaa tgaatcaccg atacgcgagc gaacgtgaag cgactgctgc
      301 tgcaaaacgt ctgcgacctg agcaacaaca tgaatggtct tcggtttccg tgtttcgtaa
      361 agtctggaaa cgggccgcct agcgatagct gtttatcgaa ttctaccggg taggggaggc
      421 gcttttccca aggcagtctg gagcatgcgc tttagcagcc ccgctgggca cttggcgcta
      481 cacaagtggc ctctggcctc gcacacattc cacatccacc ggtaggcgcc aaccggctcc
      541 gttctttggt ggccccttcg cgccaccttc tactcctccc ctagtcagga agttcccccc
      601 cgccccgcag ctcgcgtcgt gcaggacgtg acaaatggaa gtagcacgtc tcactagtct
      661 cgtgcagatg gacagcaccg ctgagcaatg gaagcgggta ggcctttggg gcagcggcca
      721 atagcagctt tgctccttcg ctttctgggc tcagaggctg ggaaggggtg ggtccggggg
      781 cgggctcagg ggcgggctca ggggcggggc gggcgcccga aggtcctccg gaggcccggc
      841 attctgcacg cttcaaaagc gcacgtctgc cgcgctgttc tcctcttcct catctccggg
      901 cctttcgacc tgcaggtcct cgccatggat cctgatgatg ttgttgattc ttctaaatct
      961 tttgtgatgg aaaacttttc ttcgtaccac gggactaaac ctggttatgt agattccatt
     1021 caaaaaggta tacaaaagcc aaaatctggt acacaaggaa attatgacga tgattggaaa
     1081 gggttttata gtaccgacaa taaatacgac gctgcgggat actctgtaga taatgaaaac
     1141 ccgctctctg gaaaagctgg aggcgtggtc aaagtgacgt atccaggact gacgaaggtt
     1201 ctcgcactaa aagtggataa tgccgaaact attaagaaag agttaggttt aagtctcact
     1261 gaaccgttga tggagcaagt cggaacggaa gagtttatca aaaggttcgg tgatggtgct
     1321 tcgcgtgtag tgctcagcct tcccttcgct gaggggagtt ctagcgttga atatattaat
     1381 aactgggaac aggcgaaagc gttaagcgta gaacttgaga ttaattttga aacccgtgga
     1441 aaacgtggcc aagatgcgat gtatgagtat atggctcaag cctgtgcagg aaatcgtgtc
     1501 aggcgatctc tttgtgaagg aaccttactt ctgtggtgtg acataattgg acaaactacc
     1561 tacagagatt taaagctcta aggtaaatat aaaattttta agtgtataat gtgttaaact
     1621 actgattcta attgtttgtg tattttagat tccaacctat ggaactgatg aatgggagca
     1681 gtggtggaat gcagatccta gagctcgctg atcagcctcg actgtgcctt ctagttgcca
     1741 gccatctgtt gtttgcccct cccccgtgcc ttccttgacc ctggaaggtg ccactcccac
     1801 tgtcctttcc taataaaatg aggaaattgc atcgcattgt ctgagtaggt gtcattctat
     1861 tctggggggt ggggtggggc aggacagcaa gggggaggat tgggaagaca atagcaggca
     1921 tgctggggat gcggtgggct ctatggcttc tgaggcggaa agaaccagct ggggctcgag
     1981 atccactagt tctagcctcg aggctagagc ggccgagttt atcctcgagc acgtgttgac
     2041 aattaatcat cggcatagta tatcggcata gtataatacg acaaggtgag gaactaaacc
     2101 atggccaagc ctttgtctca agaagaatcc accctcattg aaagagcaac ggctacaatc
     2161 aacagcatcc ccatctctga agactacagc gtcgccagcg cagctctctc tagcgacggc
     2221 cgcatcttca ctggtgtcaa tgtatatcat tttactgggg gaccttgtgc agaactcgtg
     2281 gtgctgggca ctgctgctgc tgcggcagct ggcaacctga cttgtatcgt cgcgatcgga
     2341 aatgagaaca ggggcatctt gagcccctgc ggacggtgcc gacaggtgct tctcgatctg
     2401 catcctggga tcaaagccat agtgaaggac agtgatggac agccgacggc agttgggatt
     2461 cgtgaattgc tgccctctgg ttatgtgtgg gagggctaag cacttcgtgg ccgaggagca
     2521 ggactgagaa ttccccggaa gtcagcgccc tgcaccatta tgttccggat ctgcatcgca
     2581 ggatgctgct ggctaccctg tggaacacct acatctgtat taacgaagcg ctggcattga
     2641 ccctgagtga tttttctctg gtcccgccgc atccataccg ccagttgttt accctcacaa
     2701 cgttccagta accgggcatg ttcatcatca gtaacccgta tcgtgagcat cctctctcgt
     2761 ttcatcggta tcattacccc catgaacaga aatccccctt acacggaggc atcagtgacc
     2821 aaacaggaaa aaaccgccct taacatggcc cgctttatca gaagccagac attaacgctt
     2881 ctggagaaac tcaacgagct ggacgcggat gaacaggcag acatctgtga atcgcttcac
     2941 gaccacgctg atgagcttta ccgcagctgc ctcgcgcgtt tcggtgatga cggtgaaaac
     3001 ctctgacaca tgcagctccc ggagacggtc acagcttgtc tgtaagcgga tgccgggagc
     3061 agacaagccc gtcagggcgc gtcagcgggt gttggcgggt gtcggggcgc agccatgacc
     3121 cagtcacgta gcgatagcgg agtgtatact ggcttaacta tgcggcatca gagcagattg
     3181 tactgagagt gcaccatatg cggtgtgaaa taccgcacag atgcgtaagg agaaaatacc
     3241 gcatcaggcg ctcttccgct tcctcgctca ctgactcgct gcgctcggtc gttcggctgc
     3301 ggcgagcggt atcagctcac tcaaaggcgg taatacggtt atccacagaa tcaggggata
     3361 acgcaggaaa gaacatgtga gcaaaaggcc agcaaaaggc caggaaccgt aaaaaggccg
     3421 cgttgctggc gtttttccat aggctccgcc cccctgacga gcatcacaaa aatcgacgct
     3481 caagtcagag gtggcgaaac ccgacaggac tataaagata ccaggcgttt ccccctggaa
     3541 gctccctcgt gcgctctcct gttccgaccc tgccgcttac cggatacctg tccgcctttc
     3601 tcccttcggg aagcgtggcg ctttctcata gctcacgctg taggtatctc agttcggtgt
     3661 aggtcgttcg ctccaagctg ggctgtgtgc acgaaccccc cgttcagccc gaccgctgcg
     3721 ccttatccgg taactatcgt cttgagtcca acccggtaag acacgactta tcgccactgg
     3781 cagcagccac tggtaacagg attagcagag cgaggtatgt aggcggtgct acagagttct
     3841 tgaagtggtg gcctaactac ggctacacta gaaggacagt atttggtatc tgcgctctgc
     3901 tgaagccagt taccttcgga aaaagagttg gtagctcttg atccggcaaa caaaccaccg
     3961 ctggtagcgg tggttttttt gtttgcaagc agcagattac gcgcagaaaa aaaggatctc
     4021 aagaagatcc tttgatcttt tctacggggt ctgacgctca gtggaacgaa aactcacgtt
     4081 aagggatttt ggtcatgaga ttatcaaaaa ggatcttcac ctagatcctt ttaaattaaa
     4141 aatgaagttt taaatcaatc taaagtatat atgagtaaac ttggtctgac agttaccaat
     4201 gcttaatcag tgaggcacct atctcagcga tctgtctatt tcgttcatcc atagttgcct
     4261 gactccccgt cgtgtagata actacgatac gggagggctt accatctggc cccagtgctg
     4321 caatgatacc gcgagaccca cgctcaccgg ctccagattt atcagcaata aaccagccag
     4381 ccggaagggc cgagcgcaga agtggtcctg caactttatc cgcctccatc cagtctatta
     4441 attgttgccg ggaagctaga gtaagtagtt cgccagttaa tagtttgcgc aacgttgttg
     4501 ccattgctgc aggcatcgtg gtgtcacgct cgtcgtttgg tatggcttca ttcagctccg
     4561 gttcccaacg atcaaggcga gttacatgat cccccatgtt gtgcaaaaaa gcggttagct
     4621 ccttcggtcc tccgatcgtt gtcagaagta agttggccgc agtgttatca ctcatggtta
     4681 tggcagcact gcataattct cttactgtca tgccatccgt aagatgcttt tctgtgactg
     4741 gtgagtactc aaccaagtca ttctgagaat agtgtatgcg gcgaccgagt tgctcttgcc
     4801 cggcgtcaac acgggataat accgcgccac atagcagaac tttaaaagtg ctcatcattg
     4861 gaaaacgttc ttcggggcga aaactctcaa ggatcttacc gctgttgaga tccagttcga
     4921 tgtaacccac tcgtgcaccc aactgatctt cagcatcttt tactttcacc agcgtttctg
     4981 ggtgagcaaa aacaggaagg caaaatgccg caaaaaaggg aataagggcg acacggaaat
     5041 gttgaatact catactcttc ctttttcaat attattgaag catttatcag ggttattgtc
     5101 tcatgagcgg atacatattt gaatgtattt agaaaaataa acaaataggg gttccgcgca
     5161 catttccccg aaaagtgcca cctgacgtct aagaaaccat tattatcatg acattaacct
     5221 ataaaaatag gcgtatcacg aggccctttc gtcttcaaga aaattgtcga ccatagtgac
     5281 tggatatgtt gtgttttaca gtattatgta gtctgttttt tatgcaaaat ctaatttaat
     5341 atattgatat ttatatcatt ttacgtttct cgttcaactt tattatacaa agttgcggac
     5401 gcgatcgccg gcggataaca atttcacaca ggaaggtcaa ttatacggaa atgaatgata
     5461 aaacagagga tgctgggtag taaatttaaa tggtgattgt atgtggtaat gttttgtggc
     5521 gtttaaagtc tatgtagaaa ttaagtcctt gatagcaagc agataaagca tgataaaatg
     5581 tgagcagtgg acctggaaag ttgaatcttt atcttttttt tttttttatg gcagtctaac
     5641 atactgaatg gttgatgcta agctatacga aagggcactg ctctaacgaa gacttcgagt
     5701 cttccatgga ttaggctggc cttgagcatg tgctttcatg gagattgact ttgaacttct
     5761 gatcctccaa catccaccac actagttctg aggttgtagg tggtctctcc cacaccgggt
     5821 ttctgtggtg ctggtcaaac ccaggtcttc ttgcttgtta aacaaacatc ctaccagtga
     5881 gctgtttcca gcttttagtt tacacttggc catctcaaaa tagctacagc attgagcagg
     5941 tcggcttaaa tacagtggct ccctgttggg tagacataga atcctttgtt gttgttgttt
     6001 tgagacaggg tttctctgtg tagccctggc tgtcctagaa ctcactctgt agaccaggct
     6061 ggcctcgaac tcagagcctg cctctgcctc ccaagtgctg ggattaaagg catgcgccac
     6121 catgcctggc tacattgtgg tacttttaag atttaccatt ttactctcca gtacagaatt
     6181 tggagaattc tagtggtgaa gattgtctct cagcagtaat aatgtggaga tgtaggctct
     6241 gactttataa gctgcatagt ctaacaccat atggtatagg taaaagtctg tgattagaac
     6301 tcagctggta cagtggtatt tatccactgg ttaccaccac aggaagtcta tttaagatgt
     6361 tggtaggtgt actagtcagg gtttctattc ctgcacaaac atcatgacca agaagcaaat
     6421 tggggaggaa agggtttatt tggcttacac ttccatactg ctgctgttca tcaccaagga
     6481 agtcaggact ggaactcaag caggtcagga agcaggagct gatgcagagg ccgtggagag
     6541 atgttcctta ctggcttact cagcctgctc tcttatagaa ccaagactac cagcccagag
     6601 atggtcccac ccacaagggg ctcttccccc ttgatcacta attgagaaaa tgccttatag
     6661 ttggatctca tggaggcatt tcctcaactg cagctccttt ttctgtgata actccagctg
     6721 tgtcaagttg acacaaaact agccagtaca gtaggttttg ggcaggagct ttggggctgt
     6781 agatagagtg cttttctagc tcaaagtcta atccctgatc ctagcactgc ataaaaccag
     6841 gtatggtggt gctcacctat catcccacac ttaggaagta attcagatga gaattgcaag
     6901 gttatcctct actacatagt gaatttgaga ctagcctgga ttatatgaaa ccttgtttga
     6961 aaaaacaatc aggaaaaagt tggaagtttg tgtgcctgtg gatgctgaga ggccagaaga
     7021 ggttgttgaa tcctccagag ctggttacag gtccttttgg ggacgctcag tttgttacat
     7081 gggtgctaga atctgaactc ctgtcttcat gagggccctg taagcacctt tcatagctga
     7141 gccacctctc cagcctgctc atggtagcgt taacagaatt ggattcttgc tttgtttagt
     7201 tggggaccag ttcttgggac ctggctcaga gctacagtgt atctagtcta ttaaagacac
     7261 agacaggatg accttgattt ttgtaggcct ccagactctg gaggtagtca gttaatttgc
     7321 cacactagat cataaaagac ttagttaacc tttatttttg gttttgtgtt agattctatg
     7381 aatgaataca tacttgttca ttaccttgct agattttgac caatttcttt cctgcagttc
     7441 ttccatcttc tgtccaggtc acactcacca ccaatcagtg gctttaaaaa aagttttagt
     7501 tttattattt ttaagtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgcgtgt gcgtgtgtgg
     7561 tttgtatgtg ggtatgcaca tgagtacagg tgcccacagg gactaaagat gttgggtccc
     7621 cctagagcca gagttagagg tagttgtggg ctgcctgatg tggtgctggg aactaaactc
     7681 tggtcctctg aaagagcagt gcattctcgt agccccggag ccatctcctc agtgtgtcta
     7741 actcagtttg ctctctcaga tcctgttcgt tcatatttca cgtgcagatc tctcgttggt
     7801 ttaaactgtt gtgttctctg tatgctgcag tggaggtcct cgggcagtct gttcagttct
     7861 ctcctcccac tctgtggtgc ccgggggttg aactcaggtc atcaggcttg cattagctgc
     7921 ttttacctgc tgacatttca ctgtccccag tcttgctata cgcacaactg aggctgccct
     7981 taaatttctt gcctccatct cctgagttct gggataacag tctagtatca ccagcttcct
     8041 aatttacatt cttttgggaa tataccttga aatagaatac attaatttgg cttttttttc
     8101 cctttatgat gggggtagaa cccataagca catgtgtgct aggcaagtgt tttaaaccac
     8161 tgtaacctga taattctttt taaccttttg aataataatc tttctttttt aagatggaat
     8221 ctcatccctt actgggctgg agcccactat atagaccagt ctggcctcaa attcgcagag
     8281 gtctgcctgt tctgcctccc tgctactcat gccgcgcaca cggcggtaag ctgaggctga
     8341 gcaggaggca tagccagcta gacgctctat taatatctga gttgtaaatg ttgttctgct
     8401 gctgggaagg aggggagatt tcccaggagc tctacaagcc cactttgagt tggtctttgc
     8461 ccaacatgtg gggcgtttgt tctgtacatc cctgtgaggt cagtaggtct gtccacagag
     8521 atgccactgc ccagccctta acaagcagaa ggatagtgtt gttgtgatag tcttgaccag
     8581 tcacataccc ttagaccata tatttaaatt atacttatat gtttaaatta tatttacata
     8641 taagatttgt tatcttttcc tgataataca tattttttaa tttttcattt tatttatttt
     8701 atattccaac agtttcccct ctctcctttc ctcccagcct caccaccctg agactcccgg
     8761 ctactcttcc tccgtttcct ttcagaaaag ggctggcctc catgggtatt aaccagctat
     8821 gacatatcaa gttgcagtaa gactaggcat ttcctcttct gttaaggata gacaaggcaa
     8881 cccagtagga ggaaaggatc cacgggcagg caacagagtc agagacagct cctgcacttc
     8941 ctgttaggag tcccaccaga agaccaagct acacaactgt tacatatatg cggagagcct
     9001 cgttggtccc atgcaggctc cctgattggc agtgcagtca ctgtgaaccc cgatgggctt
     9061 ggattgattg attttttgtg gattttcttg tggtgtcctt gaccccactg gctcctacaa
     9121 tccttccccc tcttcttagg attccctaag ctctgcctaa tgtttggctg tgggtctcca
     9181 agtctgtttc catcagttcc tgggtgaagc ctctctgatg gcagtttaga ccatacatat
     9241 gttataccga cttggtgtca cccggagacc ctgcctaggg agaagaatat atgccagcat
     9301 ccctccttac tgctgcagga tggctcagga atattcctgt gctttaaatg gggtgccagt
     9361 ggctcttggt tacacgtgga gctttgtgct gtagtaagtc tcatgttgaa cctgctttgc
     9421 tgtgattaag agggagttca gccatgccac agtttctgga ctgtgtgtgg tttaatggca
     9481 aggtgatttg ccccacaact ttgtgaaatg gaagataatt tatagtaagt atctgcctaa
     9541 gccaataagc ttgtttagag gattagcttg atggcttgtg cagaacttgc agatctgtct
     9601 cttcagggct tttggggcca aggcaggttg agagaggtca aggcccccct ggcagacagg
     9661 cactagcagg tctttttggc tacagagcac tgactgccat gtattctgga ttgtggtgtg
     9721 tatagctgca tgtctggctg gaggcctgtg ccttcttgga gtcttttact acaatctgtt
     9781 actgtactat acagatcttt gtcttattag cttgactact agatgtaaac cttttattca
     9841 ccttttctgt aggtgacaag gctcttgatg gctacagtaa aaagaagtat gtctgcaaat
     9901 tgctcttcat ctttctcctt ggtcatgaca ttgactttgg acacatggaa gctgtgaatc
     9961 ttctgagctc aaacagatac acggaaaagc agattgtgag tatggttgag gggcagggcc
    10021 ctgtgcctta tgtgcagttt gcagactcct tcttcctctc tgtcgcatgt tgggtgccaa
    10081 ccacctgtgc atctggcctg tgttactgcc tggtgctgat tccttgtagt cacgcccatc
    10141 ccaacgtggt tctctgcttc tgaggaccag tggtgcccag gacggactcg gatggctggc
    10201 tctcttccca ctgctgcttt ctgttggctt aggctgctgg attctctgtg ctcacacccc
    10261 tgtgtctgtt gcccacagcc tcagtgcctt cttttcactg ggccttgcta gagagtaaag
    10321 tgccagcagt cactttactc catggccttt tgcatgactg cttgaaactt gcgtctatgc
    10381 cacagggaca ggcaataaag ccagaaaagg tttggtctct tctttgcagg ctgctcaaac
    10441 ttgcttaggt ttagaatttc agctctgcat tctgttatag taaggctgtc aataacagct
    10501 ttctcttttg gttaaaaatt taacttaaca gaaattaaaa aataagccaa atatcttagg
    10561 atttttttgt taaaaaaatt agccttttct gttttcaggc tccacatgct taccttgtaa
    10621 gtgatagatc gatgatgtga gactgggttt gaacagataa aggcgcataa cgataccacg
    10681 atatcaacaa gtttgtacaa aaaagcaggc tggcgccgga accgaagttc ctattccgaa
    10741 gttcctattc tctagaaagt ataggaactt cgaacccttt cccacaccac cctccacact
    10801 tgccccaaac actgccaact atgtaggagg aaggggttgg gactaacaga agaacccgtt
    10861 gtggggaagc tgttgggagg gtcactttat gttcttgccc aaggtcagtt gggtggcctg
    10921 cttctgatga ggtggtccca aggtctgggg tagaaggtga gagggacagg ccaccaaggt
    10981 cagccccccc cccctatccc ataggagcca ggtccctctc ctggacagga agactgaagg
    11041 ggagatgcca gagactcagt gaagcctggg gtaccctatt ggagtccttc aaggaaacaa
    11101 acttggcctc accaggcctc agccttggct cctcctggga actctactgc ccttgggatc
    11161 cccttgtagt tgtgggttac ataggaaggg ggacgggatt ccccttgact ggctagccta
    11221 ctcttttctt cagtcttctc catctcctct cacctgtctc tcgacccttt ccctaggata
    11281 gacttggaaa aagataaggg gagaaaacaa atgcaaacga ggccagaaag attttggctg
    11341 ggcattcctt ccgctagctt ttattgggat cccctagttt gtgataggcc ttttagctac
    11401 atctgccaat ccatctcatt ttcacacaca cacacaccac tttccttctg gtcagtgggc
    11461 acatgtccag cctcaagttt atatcaccac ccccaatgcc caacacttgt atggccttgg
    11521 gcgggtcatc ccccccccca cccccagtat ctgcaacctc aagctagctt gggtgcgttg
    11581 gttgtggata agtagctaga ctccagcaac cagtaacctc tgccctttct cctccatgac
    11641 aaccaggtcc caggtcccga aaaccaaaga agaagaaccc taacaaagag gacaagcggc
    11701 ctcgcacagc cttcactgct gagcagctcc agaggctcaa ggctgagttt cagaccaaca
    11761 ggtacctgac agagcagcgg cgccagagtc tggcacagga gctcggtacc cggaagatct
    11821 ggactctaga gaattccgcc cctctccctc ccccccccct aacgttactg gccgaagccg
    11881 cttggaataa ggccggtgtg cgtttgtcta tatgttattt tccaccatat tgccgtcttt
    11941 tggcaatgtg agggcccgga aacctggccc tgtcttcttg acgagcattc ctaggggtct
    12001 ttcccctctc gccaaaggaa tgcaaggtct gttgaatgtc gtgaaggaag cagttcctct
    12061 ggaagcttct tgaagacaaa caacgtctgt agcgaccctt tgcaggcagc ggaacccccc
    12121 acctggcgac aggtgcctct gcggccaaaa gccacgtgta taagatacac ctgcaaaggc
    12181 ggcacaaccc cagtgccacg ttgtgagttg gatagttgtg gaaagagtca aatggctctc
    12241 ctcaagcgta ttcaacaagg ggctgaagga tgcccagaag gtaccccatt gtatgggatc
    12301 tgatctgggg cctcggtgca catgctttac atgtgtttag tcgaggttaa aaaacgtcta
    12361 ggccccccga accacgggga cgtggttttc ctttgaaaaa cacgatgata agcttgccac
    12421 aaccatggaa gatcccgtcg ttttacaacg tcgtgactgg gaaaaccctg gcgttaccca
    12481 acttaatcgc cttgcagcac atcccccttt cgccagctgg cgtaatagcg aagaggcccg
    12541 caccgatcgc ccttcccaac agttgcgcag cctgaatggc gaatggcgct ttgcctggtt
    12601 tccggcacca gaagcggtgc cggaaagctg gctggagtgc gatcttcctg aggccgatac
    12661 tgtcgtcgtc ccctcaaact ggcagatgca cggttacgat gcgcccatct acaccaacgt
    12721 gacctatccc attacggtca atccgccgtt tgttcccacg gagaatccga cgggttgtta
    12781 ctcgctcaca tttaatgttg atgaaagctg gctacaggaa ggccagacgc gaattatttt
    12841 tgatggcgtt aactcggcgt ttcatctgtg gtgcaacggg cgctgggtcg gttacggcca
    12901 ggacagtcgt ttgccgtctg aatttgacct gagcgcattt ttacgcgccg gagaaaaccg
    12961 cctcgcggtg atggtgctgc gctggagtga cggcagttat ctggaagatc aggatatgtg
    13021 gcggatgagc ggcattttcc gtgacgtctc gttgctgcat aaaccgacta cacaaatcag
    13081 cgatttccat gttgccactc gctttaatga tgatttcagc cgcgctgtac tggaggctga
    13141 agttcagatg tgcggcgagt tgcgtgacta cctacgggta acagtttctt tatggcaggg
    13201 tgaaacgcag gtcgccagcg gcaccgcgcc tttcggcggt gaaattatcg atgagcgtgg
    13261 tggttatgcc gatcgcgtca cactacgtct gaacgtcgaa aacccgaaac tgtggagcgc
    13321 cgaaatcccg aatctctatc gtgcggtggt tgaactgcac accgccgacg gcacgctgat
    13381 tgaagcagaa gcctgcgatg tcggtttccg cgaggtgcgg attgaaaatg gtctgctgct
    13441 gctgaacggc aagccgttgc tgattcgagg cgttaaccgt cacgagcatc atcctctgca
    13501 tggtcaggtc atggatgagc agacgatggt gcaggatatc ctgctgatga agcagaacaa
    13561 ctttaacgcc gtgcgctgtt cgcattatcc gaaccatccg ctgtggtaca cgctgtgcga
    13621 ccgctacggc ctgtatgtgg tggatgaagc caatattgaa acccacggca tggtgccaat
    13681 gaatcgtctg accgatgatc cgcgctggct accggcgatg agcgaacgcg taacgcgaat
    13741 ggtgcagcgc gatcgtaatc acccgagtgt gatcatctgg tcgctgggga atgaatcagg
    13801 ccacggcgct aatcacgacg cgctgtatcg ctggatcaaa tctgtcgatc cttcccgccc
    13861 ggtgcagtat gaaggcggcg gagccgacac cacggccacc gatattattt gcccgatgta
    13921 cgcgcgcgtg gatgaagacc agcccttccc ggctgtgccg aaatggtcca tcaaaaaatg
    13981 gctttcgcta cctggagaga cgcgcccgct gatcctttgc gaatacgccc acgcgatggg
    14041 taacagtctt ggcggtttcg ctaaatactg gcaggcgttt cgtcagtatc cccgtttaca
    14101 gggcggcttc gtctgggact gggtggatca gtcgctgatt aaatatgatg aaaacggcaa
    14161 cccgtggtcg gcttacggcg gtgattttgg cgatacgccg aacgatcgcc agttctgtat
    14221 gaacggtctg gtctttgccg accgcacgcc gcatccagcg ctgacggaag caaaacacca
    14281 gcagcagttt ttccagttcc gtttatccgg gcaaaccatc gaagtgacca gcgaatacct
    14341 gttccgtcat agcgataacg agctcctgca ctggatggtg gcgctggatg gtaagccgct
    14401 ggcaagcggt gaagtgcctc tggatgtcgc tccacaaggt aaacagttga ttgaactgcc
    14461 tgaactaccg cagccggaga gcgccgggca actctggctc acagtacgcg tagtgcaacc
    14521 gaacgcgacc gcatggtcag aagccgggca catcagcgcc tggcagcagt ggcgtctggc
    14581 ggaaaacctc agtgtgacgc tccccgccgc gtcccacgcc atcccgcatc tgaccaccag
    14641 cgaaatggat ttttgcatcg agctgggtaa taagcgttgg caatttaacc gccagtcagg
    14701 ctttctttca cagatgtgga ttggcgataa aaaacaactg ctgacgccgc tgcgcgatca
    14761 gttcacccgt gcaccgctgg ataacgacat tggcgtaagt gaagcgaccc gcattgaccc
    14821 taacgcctgg gtcgaacgct ggaaggcggc gggccattac caggccgaag cagcgttgtt
    14881 gcagtgcacg gcagatacac ttgctgatgc ggtgctgatt acgaccgctc acgcgtggca
    14941 gcatcagggg aaaaccttat ttatcagccg gaaaacctac cggattgatg gtagtggtca
    15001 aatggcgatt accgttgatg ttgaagtggc gagcgataca ccgcatccgg cgcggattgg
    15061 cctgaactgc cagctggcgc aggtagcaga gcgggtaaac tggctcggat tagggccgca
    15121 agaaaactat cccgaccgcc ttactgccgc ctgttttgac cgctgggatc tgccattgtc
    15181 agacatgtat accccgtacg tcttcccgag cgaaaacggt ctgcgctgcg ggacgcgcga
    15241 attgaattat ggcccacacc agtggcgcgg cgacttccag ttcaacatca gccgctacag
    15301 tcaacagcaa ctgatggaaa ccagccatcg ccatctgctg cacgcggaag aaggcacatg
    15361 gctgaatatc gacggtttcc atatggggat tggtggcgac gactcctgga gcccgtcagt
    15421 atcggcggaa ttccagctga gcgccggtcg ctaccattac cagttggtct ggtgtcaaaa
    15481 ataataataa ccgggcaggg gggatctaag ctctagataa gtaatgatca taatcagcca
    15541 tatcacatct gtagaggttt tacttgcttt aaaaaacctc ccacacctcc ccctgaacct
    15601 gaaacataaa atgaatgcaa ttgttgttgt taacttgttt attgcagctt ataatggtta
    15661 caaataaagc aatagcatca caaatttcac aaataaagca tttttttcac tgcattctag
    15721 ttgtggtttg tccaaactca tcaatgtatc ttatcatgtc tggatccgga ataacttcgt
    15781 atagcataca ttatacgaag ttatgtttaa acggcgcgcc ccggaattcg ccttctgcag
    15841 gagcgtacag aacccagggc cctggcaccc gtgcagaccc tggcccaccc cacctgggcg
    15901 ctcagtgccc aagagatgtc cacacctagg atgtcccgcg gtgggtgggg ggcccgagag
    15961 acgggcaggc cgggggcagg cctggccatg cggggccgaa ccgggcactg cccagcgtgg
    16021 gcgcgggggc cacggcgcgc gcccccagcc cccgggccca gcaccccaag gcggccaacg
    16081 ccaaaactct ccctcctcct cttcctcaat ctcgctctcg ctcttttttt ttttcgcaaa
    16141 aggaggggag agggggtaaa aaaatgctgc actgtgcggc gaagccggtg agtgagcggc
    16201 gcggggccaa tcagcgtgcg ccgttccgaa agttgccttt tatggctcga gcggccgcgg
    16261 cggcgcccta taaaacccag cggcgcgacg cgccaccacc gccgagaccg cgtccgcccc
    16321 gcgagcacag agcctcgcct ttgccgatcc tctagagtcg agatccgccg ccaccatgat
    16381 tgaacaagat ggattgcacg caggttctcc ggccgcttgg gtggagaggc tattcggcta
    16441 tgactgggca caacagacaa tcggctgctc tgatgccgcc gtgttccggc tgtcagcgca
    16501 ggggcgcccg gttctttttg tcaagaccga cctgtccggt gccctgaatg aactgcagga
    16561 cgaggcagcg cggctatcgt ggctggccac gacgggcgtt ccttgcgcag ctgtgctcga
    16621 cgttgtcact gaagcgggaa gggactggct gctattgggc gaagtgccgg ggcaggatct
    16681 cctgtcatct caccttgctc ctgccgagaa agtatccatc atggctgatg caatgcggcg
    16741 gctgcatacg cttgatccgg ctacctgccc attcgaccac caagcgaaac atcgcatcga
    16801 gcgagcacgt actcggatgg aagccggtct tgtcgatcag gatgatctgg acgaagagca
    16861 tcaggggctc gcgccagccg aactgttcgc caggctcaag gcgcgcatgc ccgacggcga
    16921 ggatctcgtc gtgacccatg gcgatgcctg cttgccgaat atcatggtgg aaaatggccg
    16981 cttttctgga ttcatcgact gtggccggct gggtgtggcg gaccgctatc aggacatagc
    17041 gttggctacc cgtgatattg ctgaagagct tggcggcgaa tgggctgacc gcttcctcgt
    17101 gctttacggt atcgccgctc ccgattcgca gcgcatcgcc ttctatcgcc ttcttgacga
    17161 gttcttctga gcgggactct ggggttcgaa atgaccgacc aagcgacgcc caacctgcca
    17221 tcacgagatt tcgattccac cgccgccttc tatgaaaggt tgggcttcgg aatcgttttc
    17281 cgggacgccg gctggatgat cctccagcgc ggggatctca tgctggagtt cttcgcccac
    17341 cccccggatc taagctctag ataagtaatg atcataatca gccatatcac atctgtagag
    17401 gttttacttg ctttaaaaaa cctcccacac ctccccctga acctgaaaca taaaatgaat
    17461 gcaattgttg ttgttaactt gtttattgca gcttataatg gttacaaata aagcaatagc
    17521 atcacaaatt tcacaaataa agcatttttt tcactgcatt ctagttgtgg tttgtccaaa
    17581 ctcatcaatg tatcttatca tgtctggatc cgggggtacc gcgtcgagaa gttcctattc
    17641 cgaagttcct attctctaga aagtatagga acttcgtcga gataacttcg tatagcatac
    17701 attatacgaa gttatgtcga gatatctaga cccagctttc ttgtacaaag tggttgatat
    17761 ctctatagtc gcagtaggcg gatatgcata tttactagtg agtggtgcca ggcttggttc
    17821 ttgccatgat agttccctcc tatcctgaca tgaagatggt gtggcaactg agcatagatg
    17881 tgtgagctac tgagaaggaa atgatatttg gggaaggact aagtggtctg gttcccttgt
    17941 gcctctgact ttgcacgtat tttagtggga atgctgcatc agggctgggt ggtgcaaaag
    18001 tgctgatcac tggtacatgt ccgcgtctct gtggcatcca ctgggacgct gctagaggct
    18061 ttcctggctt ccttctctgc actgtgtgtt aggcgtcttg tcataagctc tttgtccccg
    18121 ccttctggaa atacagggct accttttcat ctctgtattg gtgaactcga atagtgaact
    18181 gatccggttg attaacaatg ccatcaagaa tgacctggcc agccgcaatc ctacgtttat
    18241 gggtctcgcc ctgcactgca ttgccaatgt gggtagccgt gagatggcgg aggccttcgc
    18301 cggagagatc cccaagatcc tcgtggcagg gtatgtatct gggtgctgtg gaggggcagc
    18361 atgcacttct tctaaacaca ctccactgtg tgtagtgagg gatgtcagga aggcctgcta
    18421 tagagctctg cctgagatca ctgagacctg atcacagaag gagaccctct tagcctgcct
    18481 gcctagaaag gactgcaggg agaaagacaa cgttgtttgg tataagagat ggcgcaacgc
    18541 aattaatgat aacttcgtat agcatacatt atacgaagtt atggtctgag ctcgccatca
    18601 gttcagccaa gcccttgttt tgttttgttt tcttaagatt tattttatgt atgtgagtac
    18661 actgtagctc tcttcagaca caccagaaga gggcatcaga tcccatgaca gatggttgtg
    18721 agccatcatg tggttgctgg gaattgaact caggacctca ggaagagcag ccagtgctct
    18781 taactgctga gccatctctc cagcccaggt caagcccttg tgtattgaga attctgcatc
    18841 atctttcccc tcagttcatt tagagagctg ccaagtggtg ttaaggggtc gttctggaag
    18901 agcttgaagc agccctgggc cattttgggc ctcagggttg gcagaggcaa ggccagcttc
    18961 tgcctggttg tgtctttatg ctgttgtgta gctagtccac agacagtggt tacattcatc
    19021 atggtccagg agacaggata ggacaattgt taatgaactt aacaggatgt caaggccctg
    19081 ggagcagtgg ctgtagccct ctgttactgt gaagctggaa tacagggagg ccagagctag
    19141 cttaccttct ctacctagtc agccatcttg ggggaaatgg gtggggccga cacagaacaa
    19201 atttatcgtt ttcatagtgg agtgcctacc cctgtcatct agtaggcaga ggtctaagat
    19261 gctacaagtt gtgtcctatg catgtcacag gcacaaagca gagaacactg caggtctctg
    19321 tcactgagct gtggtgcagg aactttaagc caacccttgg cacctcaacc ttgagcactg
    19381 tgaagcacag gcaggtagag gaaccaggct ggagagaact gccctgtgga aacaggttca
    19441 caaatataga cgtgggcccc aggatattga tgaagagaac ccattacaga gctgagaggc
    19501 tgtgggaagt tcaaagactg actattgtag actgtaagca gaaaccatag agaacactga
    19561 ggagtttgag gtaggagatt acagtgggtg ttgggataga agaagggcta gagttcagac
    19621 cagagaggaa ggaagttggg caggatgcaa gtgtgagctg ctagcaaggc ctccctggcc
    19681 atcttcccta atagtcacca tgaagtcctg tgacagacac ctgagtgttg cctgctgtgc
    19741 tccatcaggg atcgtggctc agatgtctct gttacattgc tgccctctgg cattcccaca
    19801 gggctgctct aatggaggaa gtacagacag ggtaatcctt gaaaaacact ggaggaatag
    19861 gagtatttcc tgaactaccc aagagtacat gcagagtggc cacaaggccc agtgcggagt
    19921 aaaggttctt tagcagggga caggtagttc tcccatttag agcatgttgg gctgtaggga
    19981 cagttcatgg gcaaagctta ctatgcaccc tttaagtgag tgatggaacc ccacagagca
    20041 caaggtgtct ctgtgagtgg tgtccgagca tcgtggttgt aaggtgctgg gtagtgtggc
    20101 tcctgagatg ggagtccagt ggctgtagtt ggtggagtag ttccgtcagc agttaggatg
    20161 tgaggcttcg gagggtggtg acattggtac ctgggacaca gtagaggatc agaaagatcc
    20221 ttcgacagct gggagctgct ctgggcacag tgggtttatg aggctgctct gtgtccttac
    20281 ttctgggatg gcaagtgctt gctccttttc tctgagctgt ctgttaacat cagcctggaa
    20341 acaagaggag atggcctcct ggttcagcat cctggtccgc aggcccttct ccttcttctc
    20401 agcacagctg tagttcccac cttagtgcct taaggattcc agctggttct ctccagctat
    20461 ctccccctcc tgatacaagg tttcactatg cagctttggc tgtccctaga attcactatg
    20521 aagaccaggc tgacctcaga gtcacagaga tccacctgcc tgtctcccaa gttctgggat
    20581 taaaggcgtg ggccactatg cctggctttc cagctggttc ccatggggat gttctgatgg
    20641 cctcctccaa ctaacatctt tggtcagtct ggtggttttt tttttttttt tccctccact
    20701 gtttgtttct ttgactgttt ttgaggcagg ttctcagtct gtagtcccct ttgccctgga
    20761 agtcacagag atcatcctgc ctctgcccct gagtgctagg attaaagaca tgtgtcatca
    20821 cacttgacct ctttcctact tcttagcagg gtctggtagg gtgaagggga gcgagccccc
    20881 agaactcctg tcttcaacag agcagaaaac agctgcctcc ctgcttggtg tctgcaccca
    20941 cttacagctt tgttcttctg gcctctgagt ggccttggat ggagaagaga aggctggaag
    21001 gcagcaactg tgtgtgtgtg tgtgtgtgtg agagagagag agagagatat gatgtgaagc
    21061 tacaggctgg gccaggacac acgtgctttt tcttaagact ttatacttag atttgggcat
    21121 gatgacttag acttgtaatc ttagcattca ggaggttgag acaggagaat ggagtttgag
    21181 aagagtgtat gataaatgat ggtaccccat atcaaataac accaaaaacc caaaacaaac
    21241 gagacctact tttcaccagc acaagacagt ttgagcctac ttcctcagca tagtggagca
    21301 gggtgaagtg tggggagcag gacacatttg taggcaagag aagaaaccac tggtatttca
    21361 ggcctccgtt ctgttcctgc tgcaatgaat tggggtgggg ttggggtaat cctatggttc
    21421 agagggggag catcattgta caaaaaagtc cattttgtat tcagtgtcca ggaggggatg
    21481 agaatttgat gtcctggaag ctacacaaca aatagtgcag gcttttgtct gtgggttggt
    21541 gtcttgcttg aaatgtcctt gagcgtgacc tgtgcaggcc ttcctgaccc actggtctcc
    21601 tggtgaactt catgtgcccc ccccacgaag ctccattctc tgcttggctt agcttgtggt
    21661 accttgagaa gccaccgttc tcccgagcga ctgatgatgt ctgttttcta gagataccat
    21721 ggatagtgtg aagcagagcg cagccctgtg cttgttacgc ctgtacagga catcacctga
    21781 cctagttccc atgggcgact ggacatctcg tgtggtacac ctcctcaatg accagcactt
    21841 ggtaagtgtc tgagtttcat tctgttctta atcacccagt aacctttcca gaagggcatt
    21901 gtagaagcgg tccattcaga gtctcaggat gatgaaggtg atgcactgtc tcctctgcag
    21961 catcttcctg cagcaggctt ctccagggac tccatctagc agggctgttc ccactcagct
    22021 cctatgtccc cacatgctgc ttgtgcgggg ctgtgatgtg tgtattccac cttttggcta
    22081 aactccactg tgtaagtctt actaacttag ccattttaca gaagactgga aggtctgtga
    22141 tttggtgagt atggctgctc agctcagctg ggtgggaagc agctgtgaac tgtgacctct
    22201 gctgcttaga ctgctgaaca agtgggtctg atgacctgct gggtcaggca agtatgtgag
    22261 atagttaccc tcacccctgg gcaaatctgc tgtgagagtt aaaaaaaaaa gattgttaga
    22321 tgcatatcta ggccacag
//