Quick website overview
The International Mouse Phenotyping Consortium (IMPC) is an international infrastructure aiming to identify the function of every gene in the mouse genome by phenotyping mouse knockout lines for all 20,000 or so protein-coding genes. Our database is continously growing as data is being generated. A brief description of the project can be found here, and consortium publications are listed here. The IMPC research endeavour involves mice production, phenotyping and data analysis using customised procedures. The data the IMPC is collecting allows to identify the physiological systems that are disrupted when a gene is disabled and thus generate gene-phenotype associations.
This website supports the IMPC research by capturing, storing and disseminating the IMPC processes, data and annotations to the scientific community and the public. Our search tool, the gene pages and the phenotype pages are central to how our website is organised. The website allows users to search for a gene to find what phenotypes are associated with it or, alternatively, search for a phenotype to discover the genes that have been associated to it. It is also possible to search for phenotyping protocols, disease models and publications featuring IMPC alleles or data, including those from the consortium. Finally, the IMPC blog provides information on recent relevant publications, interviews and news.